Keith Ashman

Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7 (2004)

Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...

Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....

Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7 (2004)

Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...

Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....

Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7 (2004)

Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...

Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....

Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7 (2004)

Gruenheid, Samantha, Sekirov, Inna, Thomas, Nikhil A., Deng, Wanyin, O'Donnell, Paul, Goode, David, ...

Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 uses a specialized protein translocation apparatus, the type III secretion system (TTSS), to deliver bacterial effector proteins into host cells....

A Comparative Study of Globular Cluster Systems in UGC 9799 and NGC 1129 (2001)

Lee, Myung Gyoon, Kim, Eunhyeuk, Geisler, Doug, Bridges, Terry, Ashman, Keith

We present a preliminary analysis of HST-WFPC2 observations of globular cluster systems in the two brightest galaxies, UGC 9799 (cD) and NGC 1129 (non-cD), located in the center of rich clusters.

Globular Clusters as Probes of the Virgo gE NGC 4472 (2000)

Bridges, Terry, Ashman, Keith, Beasley, Mike, Sharples, Ray, Geisler, Doug, Hanes, Dave, ...

We present radial velocities for 144 globular clusters around the Virgo gE NGC 4472 (M49), and ages and metallicities from co-added spectra of 131 clusters. We confirm our earlier finding that the...

Chemical synthesis, expression and product assessment of a gene coding for biologically active human tumour necrosis factor {alpha} (1989)

Ashman, Keith, Matthews, Nicholas, Frank, Rainer W.

A gene encoding human tumour necrosis factor α (TNF-α) has been chemically synthesized, cloned and expressed to yield a biologically active protein in Escherichia coli. The 480-bp gene was...

Existence of distinct tyrosylprotein sulfotransferase genes: Molecular characterization of tyrosylprotein sulfotransferase-2

Beisswanger, Roland, Corbeil, Denis, Vannier, Christian, Thiele, Christoph, Dohrmann, Ulrike, Kellner, Roland, ...

Tyrosylprotein sulfotransferase (TPST) is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation...

Vaccinia virus infection disrupts microtubule organization and centrosome function

Ploubidou, Aspasia, Moreau, Violaine, Ashman, Keith, Reckmann, Inge, González, Cayetano, Way, Michael

We examined the role of the microtubule cytoskeleton during vaccinia virus infection. We found that newly assembled virus particles accumulate in the vicinity of the microtubule-organizing centre in...

Dissecting virulence: Systematic and functional analyses of a pathogenicity island

Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...

Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...

A novel 110 kDa form of myosin XVIIIA (MysPDZ) is tyrosine-phosphorylated after colony-stimulating factor-1 receptor signalling.

Cross, Maddalena, Csar, Xavier F, Wilson, Nicholas J, Manes, Gaël, Addona, Theresa A, Marks, Denese C, ...

Macrophage colony-stimulating factor (M-CSF or CSF-1) controls the development of macrophage lineage cells via activation of its tyrosine kinase receptor, c-Fms. After adding CSF-1 to M1 myeloid...

Existence of distinct tyrosylprotein sulfotransferase genes: Molecular characterization of tyrosylprotein sulfotransferase-2

Beisswanger, Roland, Corbeil, Denis, Vannier, Christian, Thiele, Christoph, Dohrmann, Ulrike, Kellner, Roland, ...

Tyrosylprotein sulfotransferase (TPST) is a 54- to 50-kDa integral membrane glycoprotein of the trans-Golgi network found in essentially all tissues investigated, catalyzing the tyrosine O-sulfation...

Vaccinia virus infection disrupts microtubule organization and centrosome function

Ploubidou, Aspasia, Moreau, Violaine, Ashman, Keith, Reckmann, Inge, González, Cayetano, Way, Michael

We examined the role of the microtubule cytoskeleton during vaccinia virus infection. We found that newly assembled virus particles accumulate in the vicinity of the microtubule-organizing centre in...

Dissecting virulence: Systematic and functional analyses of a pathogenicity island

Deng, Wanyin, Puente, José L., Gruenheid, Samantha, Li, Yuling, Vallance, Bruce A., Vázquez, Alejandra, ...

Bacterial pathogenicity islands (PAI) often encode both effector molecules responsible for disease and secretion systems that deliver these effectors to host cells. Human enterohemorrhagic...

A novel 110 kDa form of myosin XVIIIA (MysPDZ) is tyrosine-phosphorylated after colony-stimulating factor-1 receptor signalling.

Cross, Maddalena, Csar, Xavier F, Wilson, Nicholas J, Manes, Gaël, Addona, Theresa A, Marks, Denese C, ...

Macrophage colony-stimulating factor (M-CSF or CSF-1) controls the development of macrophage lineage cells via activation of its tyrosine kinase receptor, c-Fms. After adding CSF-1 to M1 myeloid...