Kelly C. Thome

Human CDC6/Cdc18 Associates with Orc1 and Cyclin-cdk and Is Selectively Eliminated from the Nucleus at the Onset of S Phase

Saha, Partha, Chen, Junjie, Thome, Kelly C., Lawlis, Stephanie J., Hou, Zhi-hui, Hendricks, Marvin, ...

In a two-hybrid screen for proteins that interact with human PCNA, we identified and cloned a human protein (hCdc18) homologous to yeast CDC6/Cdc18 and human Orc1. Unlike yeast, in which the rapid...

Loss of Heterozygosity at the Ink4a/Arf Locus Facilitates Abelson Virus Transformation of Pre-B Cells

Mostecki, Justin, Halgren, Anne, Radfar, Arash, Sachs, Zohar, Ravitz, James, Thome, Kelly C., ...

In many tumor systems, analysis of cells for loss of heterozygosity (LOH) has helped to clarify the role of tumor suppressor genes in oncogenesis. Two important tumor suppressor genes, p53 and the...

Human CDC6/Cdc18 Associates with Orc1 and Cyclin-cdk and Is Selectively Eliminated from the Nucleus at the Onset of S Phase

Saha, Partha, Chen, Junjie, Thome, Kelly C., Lawlis, Stephanie J., Hou, Zhi-hui, Hendricks, Marvin, ...

In a two-hybrid screen for proteins that interact with human PCNA, we identified and cloned a human protein (hCdc18) homologous to yeast CDC6/Cdc18 and human Orc1. Unlike yeast, in which the rapid...

Loss of Heterozygosity at the Ink4a/Arf Locus Facilitates Abelson Virus Transformation of Pre-B Cells

Mostecki, Justin, Halgren, Anne, Radfar, Arash, Sachs, Zohar, Ravitz, James, Thome, Kelly C., ...

In many tumor systems, analysis of cells for loss of heterozygosity (LOH) has helped to clarify the role of tumor suppressor genes in oncogenesis. Two important tumor suppressor genes, p53 and the...