VarScan: variant detection in massively parallel sequencing of individual and pooled samples (2009)
Koboldt, Daniel C., Chen, Ken, Wylie, Todd, Larson, David E., McLellan, Michael D., Mardis, Elaine R., ...
Summary: Massively parallel sequencing technologies hold incredible promise for the study of DNA sequence variation, particularly the identification of variants affecting human disease. The...
Somatic mutations affect key pathways in lung adenocarcinoma (2008)
Ding, Li, Getz, Gad, Wheeler, David A., Mardis, Elaine R., McLellan, Michael D., Cibulskis, Kristian, ...
Determining the genetic basis of cancer requires comprehensive analyses of large collections of histopathologically well- classified primary tumours. Here we report the results of a collaborative...
LANDMARK-BASED SPEECH RECOGNITION: REPORT OF THE 2004 (2008)
Johns Hopkins, Summer Workshop, Mark Hasegawa-johnson, James Baker, Sarah Borys, Ken Chen, ...
Three research prototype speech recognition systems are described, all of which use recently developed methods from artificial intelligence (specifically support vector machines, dynamic Bayesian...
Somatic mutations affect key pathways in lung adenocarcinoma (2008)
Ding, Li, Getz, Gad, Wheeler, David A., Mardis, Elaine R., McLellan, Michael D., Cibulskis, Kristian, ...
On The Design Of A New Scalable Reliable Multicast Transport Protocol (2007)
Stephan Block, Ken Chen, Ahmed Serhrouchni, Ecole Nationale Superieure, M. H. Sherif
This document presents the design and performance evaluation of a scalable, reliable, oneto -many multicast transport protocol. We show through simulation that it scales extremely well to a very big...
Some Design Issues of SRMTP, a Scalable Reliable Multicast Transport Protocol (2007)
Stephan Block, Ken Chen, Philippe Godlewski, Ahmed Serhrouchni
. In this paper, we propose a transport layer protocol for oneto -many multicast that is designed to have good scalability properties in large receiver groups and provides reliable transmission....
An Approximate Analysis of Waiting Time in Multi-classes M=G=1=:=EDF Queues (2007)
Ken Chen, Laurent Decreusefond
Abstract This paper deals with non-preemptive and work-conserving M=G=1 queues ordered by the Earliest-Deadline-First (EDF) queueing discipline. The EDF discipline is more and more used for handling...
McLaughlin, William A, Chen, Ken, Hou, Tingjun, Wang, Wei
Abstract Background Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available methods to...
Chen, Ken, McLellan, Michael D., Ding, Li, Wendl, Michael C., Kasai, Yumi, Wilson, Richard K., ...
Small insertions and deletions (indels) and single nucleotide polymorphisms (SNPs) are common genetic variants that are thought to be associated with a wide variety of human diseases. Owing to the...
Huang, Shenghai, Liang, Jingjing, Zheng, Mengjie, Li, Xinyi, Wang, Meiling, Wang, Ping, ...
The prion protein (PrP) level in muscle has been reported to be elevated in patients with inclusion-body myositis, polymyositis, dermatomyositis, and neurogenic muscle atrophy, but it is not clear...
Mark Hasegawa-johnson, Jennifer Cole, Ken Chen, Partha Lal, Amit Juneja, Taejin Yoon, ...
Automatic speech recognition (ASR) is like solving a crossword puzzle. Context at every level is used to resolve ambiguity: the more context we can bring to bear, the higher will be the accuracy of...
Tingjun Hou, Ken Chen, William A. McLaughlin, Benzhuo Lu, Wei Wang
Protein-protein interactions, particularly weak and transient ones, are often mediated by peptide recognition domains, such as Src Homology 2 and 3 (SH2 and SH3) domains, which bind to specific...
Performances des mécanismes de robustesse de H.264/AVC sur un lien sans fil (2006)
Benayoune, Salim, Achir, Nadjib, Boussetta, Khaled, Chen, Ken
Le standard H.264/AVC suscite depuis quelque temps un intérêt croissant de la part de la communauté réseau. D'un point de vue réseau, le principal apport de ce standard réside dans...
Une nouvelle approche pour la gestion de flux temps réels basée sur l'algorithme EDF (2006)
Pour répondre aux exigences temporelles de flux temps réels, beaucoup de techniques d'ordonnancement de paquets ont été proposées dans la littérature, pour être utilisées au niveau de...
Performances des mécanismes de robustesse de H.264/AVC sur un lien sans fil (2006)
Benayoune, Salim, Achir, Nadjib, Boussetta, Khaled, Chen, Ken
Le standard H.264/AVC suscite depuis quelque temps un intérêt croissant de la part de la communauté réseau. D'un point de vue réseau, le principal apport de ce standard réside dans...
Une nouvelle approche pour la gestion de flux temps réels basée sur l'algorithme EDF (2006)
Pour répondre aux exigences temporelles de flux temps réels, beaucoup de techniques d'ordonnancement de paquets ont été proposées dans la littérature, pour être utilisées au niveau de...
Efficient classification of multilabel and imbalanced data using min-max modular classifiers (2006)
Abstract — Many real-world applications, such as text categorization and subcellular localization of protein sequences, involve multi-label classification with imbalanced data. In this paper, we...
2.2 Speech Perception: Landmarks.............................. 9 (2005)
James Baker, Steven Greenberg, Katrin Kirchhoff, Jennifer Muller, Kemal Sönmez, Sarah Borys, ...
Some lessons from an experience with active video flow regulation (2005)
People are paying more and more attention to network infrastructures which are capable of dynamic code deployment and reconfiguration, in order to deal with the increase of network complexity both on...
Ken Chen, Mark Hasegawa-johnson, Aaron Cohen
Automatic prosody labeling is important for both speech synthesis and automatic speech understanding. Humans use both syntactic cues and acoustic cues to develop their prediction of prosody for a...
How Prosody Improves Word Recognition (2004)
Ken Chen, Mark Hasegawa-johnson
recognition. In this paper, we provide a schematic view describing how prosody can help word recognition. We provide our view in terms of a Bayesian network that models the stochastic dependence...
Multimodal Dialog Systems Research at Illinois (2003)
Levinson, Stephen E., Huang, Thomas S., Hasegawa-Johnson, Mark A., Chen, Ken, Chu, Stephen
Multimodal dialog systems research at the University of Illinois seeks to develop algorithms and systems capable of robustly extracting and adaptively combining information about the speech and...
Ken Chen, Mark Hasegawa-johnson
This paper presents a novel approach that improves the robustness of prosody dependent language modeling by leveraging the dependence between prosody and syntax. A prosody dependent language model...
Automatic Recognition of Pitch Movements Using Time-Delay Recursive Neural Network (2003)
Sung-suk Kim, Mark Hasegawa-johnson, Ken Chen
This paper proposes a novel method for the automatic recognition of pitch accents with no prior knowledge about the phonetic content of the signal (no knowledge of word or phoneme boundaries or of...
An intonational phrase boundary and pitch accent dependent speech recognizer (2003)
Ken Chen, Mark Hasegawa-johnson, Sung-suk Kim
Does prosody help word recognition? In this paper, we propose a novel probabilistic framework in which word and phoneme are dependent on prosody in a way that improves word recognition. We describe...
Steeb, Randall, Chen, Ken, Freedy, Amos
This report describes research and development centered on evaluation of information needs in supervision of remotely piloted vehicles. The selection of information for transmission and display is a...
Mohamed Kamal Omar, Ken Chen, Mark Hasegawa-johnson
This paper addresses the problem of finding a subset of the acoustic feature space that best represents the phoneme set used in a speech recognition system. A maximum mutual information approach is...
Printout.
A study of data cryptography (2001)
Facsimile of the author's original dissertation. Alternate pages blank. Includes bibliographical references.
Insook Choi (University Of Illinois At Urbana-Champaign), Geoffrey Zheng (University Of Illinois At Urbana-Champaign), Ken Chen (University Of Illinois At Urbana-Champaign)
Chu,Yee-yeen, Chen,Ken, Clark,Cynthia, Freedy,Amos
The problems addressed in this study stem from the increasing supervisory loads imposed on the operator in airborne system operations. Future aircraft will be characterized by high information loads,...
Time value functions is a new concept for the description of real-time system. In such systems time value function (TVF) is associated to each task. The value of this function taken at time t gives...
Time value functions is a new concept for the description of real-time system. In such systems time value function (TVF) is associated to each task. The value of this function taken at time t gives...
Time value functions is a new concept for the description of real-time system. In such systems time value function (TVF) is associated to each task. The value of this function taken at time t gives...
A Family of scheduling algorithms for real-time systems using time value functions (1991)
Résumé disponible dans le fichier PDF
A Family of scheduling algorithms for real-time systems using time value functions (1991)
Résumé disponible dans le fichier PDF
STUDIES ON 'PEBRINE' WITH THE PURPOSE OF DISCOVERING A NEW METHOD OF CONTROL. (1934)
DISSERTATION (PH.D.)--THE UNIVERSITY OF MICHIGAN
Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype
Schreiber-Agus, Nicole, Stein, David, Chen, Ken, Goltz, Jason S., Stevens, Leslie, DePinho, Ronald A.
Biochemical and biological activities of Myc oncoproteins are highly dependent upon their association with another basic region helix–loop–helix/leucine zipper (bHLH/LZ) protein, Max. Our...
Alland, Leila, David, Gregory, Shen-Li, Hong, Potes, Jason, Muhle, Rebecca, Lee, Hye-Chun, ...
Silencing of gene transcription involves local chromatin modification achieved through the local recruitment of large multiprotein complexes containing histone deacetylase (HDAC) activity. The...
Hou, Tingjun, Chen, Ken, McLaughlin, William A, Lu, Benzhuo, Wang, Wei
Protein-protein interactions, particularly weak and transient ones, are often mediated by peptide recognition domains, such as Src Homology 2 and 3 (SH2 and SH3) domains, which bind to specific...
Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype
Schreiber-Agus, Nicole, Stein, David, Chen, Ken, Goltz, Jason S., Stevens, Leslie, DePinho, Ronald A.
Biochemical and biological activities of Myc oncoproteins are highly dependent upon their association with another basic region helix–loop–helix/leucine zipper (bHLH/LZ) protein, Max. Our...
Alland, Leila, David, Gregory, Shen-Li, Hong, Potes, Jason, Muhle, Rebecca, Lee, Hye-Chun, ...
Silencing of gene transcription involves local chromatin modification achieved through the local recruitment of large multiprotein complexes containing histone deacetylase (HDAC) activity. The...
Hou, Tingjun, Chen, Ken, McLaughlin, William A, Lu, Benzhuo, Wang, Wei
Protein-protein interactions, particularly weak and transient ones, are often mediated by peptide recognition domains, such as Src Homology 2 and 3 (SH2 and SH3) domains, which bind to specific...
Huang, Shenghai, Liang, Jingjing, Zheng, Mengjie, Li, Xinyi, Wang, Meiling, Wang, Ping, ...
The prion protein (PrP) level in muscle has been reported to be elevated in patients with inclusion-body myositis, polymyositis, dermatomyositis, and neurogenic muscle atrophy, but it is not clear...
PolyScan: An automatic indel and SNP detection approach to the analysis of human resequencing data
Chen, Ken, McLellan, Michael D., Ding, Li, Wendl, Michael C., Kasai, Yumi, Wilson, Richard K., ...
Small insertions and deletions (indels) and single nucleotide polymorphisms (SNPs) are common genetic variants that are thought to be associated with a wide variety of human diseases. Owing to the...
Joseph, Aviva, Zheng, Jian Hua, Follenzi, Antonia, DiLorenzo, Teresa, Sango, Kaori, Hyman, Jaime, ...
The human immunodeficiency virus type 1 (HIV-1)-specific CD8 cytotoxic T-lymphocyte (CTL) response plays a critical role in controlling HIV-1 replication. Augmenting this response should enhance...
Macrophage Migration Inhibitory Factor Promotes Colorectal Cancer
He, Xing-Xiang, Chen, Ken, Yang, Jun, Li, Xiao-Yu, Gan, Huo-Ye, Liu, Cheng-Yong, ...
A growing body of evidence implicates macrophage migration inhibitory factor (MIF) in tumorigenesis and metastasis. In this study, we investigated whether MIF expression was associated with...
Cell-permeable Tat-NBD peptide attenuates rat pancreatitis and acinus cell inflammation response
Long, You-Ming, Chen, Ken, Liu, Xue-Jin, Xie, Wen-Rui, Wang, Hui
AIM: To investigate the effects of Tat-NEMO-binding domain (NBD) peptide on taurocholate-induced pancreatitis and lipopolysaccharide (LPS)-stimulated AR42J acinus cells inflammatory response in rats.
Sengupta, Tanushri, Chen, Ken, Milot, Eric, Bieker, James J.
Posttranslational modifications of transcription factors provide alternate protein interaction platforms that lead to varied downstream effects. We have investigated how the acetylation of EKLF plays...