Ken M. Simpson

Integrative analysis of RUNX1 downstream pathways and target genes (2008)

Michaud, Joëlle, Simpson, Ken M, Escher, Robert, Buchet-Poyau, Karine, Beissbarth, Tim, Carmichael, Catherine, ...

Abstract Background The RUNX1 transcription factor gene is frequently mutated in sporadic myeloid and lymphoid leukemia through translocation, point mutation or amplification. It is also responsible...

affylmGUI: a graphical user interface for linear modeling of single channel microarray data (2006)

Wettenhall, James M., Simpson, Ken M., Satterley, Keith, Smyth, Gordon K.

Summary: affylmGUI is a graphical user interface (GUI) to an integrated workflow for Affymetrix microarray data. The user is able to proceed from raw data (CEL files) to QC and pre-processing, and...

Invasion by P. falciparum Merozoites Suggests a Hierarchy of Molecular Interactions (2005)

Jake Baum, Alexander G. Maier, Robert T. Good, Ken M. Simpson, Alan F. Cowman

Central to the pathology of malaria disease are the repeated cycles of parasite invasion and destruction of human erythrocytes. In Plasmodium falciparum, the most virulent species causing malaria,...

Invasion by P. falciparum Merozoites Suggests a Hierarchy of Molecular Interactions

Baum, Jake, Maier, Alexander G, Good, Robert T, Simpson, Ken M, Cowman, Alan F

Central to the pathology of malaria disease are the repeated cycles of parasite invasion and destruction of human erythrocytes. In Plasmodium falciparum, the most virulent species causing malaria,...

Invasion by P. falciparum Merozoites Suggests a Hierarchy of Molecular Interactions

Baum, Jake, Maier, Alexander G, Good, Robert T, Simpson, Ken M, Cowman, Alan F

Central to the pathology of malaria disease are the repeated cycles of parasite invasion and destruction of human erythrocytes. In Plasmodium falciparum, the most virulent species causing malaria,...