Onozato, Yasuhiro, Kakizaki, Satoru, Iizuka, Haruhisa, Mori, Kazuyo, Takizawa, Daichi, Ohyama, Tatsuya, ...
The term "ectopic varices" is used to describe dilated portosystemic collateral veins in unusual locations other than the gastroesophageal region. We recently experienced a rare case of ectopic...
Solitary mandibular metastasis as an initial manifestation of hepatocellular carcinoma. (2006)
Teshigawara, Katsunobu, Kakizaki, Satoru, Sohara, Naondo, Hashida, Tetsu, Tomizawa, Yoshio, Sato, Ken, ...
Oral metastases from hepatocellular carcinoma are very rare. We encountered a case of hepatocellular carcinoma with a solitary metastasis to the mandible as an initial manifestation. The patient was...
Ectopic varices in a right diaphragm that ruptured into the pleural cavity. (2006)
Matsui, Masayuki, Kojima, Akira, Kakizaki, Satoru, Nagasaki, Kazumi, Sohara, Naondo, Sato, Ken, ...
The term ectopic varices is used to describe dilated portosystemic collateral veins in unusual locations other than the gastroesophageal region. We recently experienced a rare case of ectopic varices...
Kosone, Takashi, Takagi, Hitoshi, Kakizaki, Satoru, Sohara, Naondo, Horiguchi, Norio, Sato, Ken, ...
Abstract Background Transforming growth factor α (TGFα) protects against gastric mucosal injury and facilitates wound healing. However, its overexpression is known to induce hypertrophic...
mutants and the importance of residue Q50 (2004)
Matthew D. Simon, Ken Sato, Gregory A. Weiss, Kevan M. Shokat
phage display selection of engrailed homeodomain
A phage display selection of engrailed homeodomain mutants and the importance of residue Q50 (2004)
Simon, Matthew D., Sato, Ken, Weiss, Gregory A., Shokat, Kevan M.
Mutants of engrailed homeodomain (HD) that retain DNA-binding activity were isolated using a phage display selection. This selection was used to enrich for active DNA-binding clones from a complex...
COPII Coat Assembly and Selective Export from the Endoplasmic Reticulum (2004)
The coat protein complex II (COPII) generates transport vesicles that mediate protein transport from the endoplasmic reticulum (ER). Recent structural and biochemical studies have suggested that the...
Furuno, Masaaki, Sato, Ken, Kawagishi, IKuro, Homma, Michio
The Polar flagella (Pof) of Vibrio alginolyticus are surrounded by a membrane structure called a sheath. Five major proteins, whose molecular masses are 60, 47, 45, 44, and 18 kDa (named PF60, PF47,...
Faropenem enhances superoxide anion production by human neutrophils in vitro (1999)
Sato, Ken, Sato, Noriyuki, Shimizu, Hiroyuki, Tsutiya, Takahumi, Takahashi, Hiroki, Kakizaki, Satoru, ...
Neutrophils are important cellular components in the defence against infections and many studies in vitro have shown that some antibiotics affect neutrophil function. We examined the effect of...
Mori, Hiroyuki, Sugiyama, Hiroyuki, Yamanaka, Miyuki, Sato, Ken, Tagaya, Mitsuo, Mizushima, Shoji
Protein translocation across the cytoplasmic membrane of Escherichia coli is accomplished by concerted actions of the translocation ATPase SecA and the membrane-embedded SecE/Y/G complex. SecA...
Thesis (Ph. D.)--University of Colorado, 1997.
Yamazaki, Soh, Sato, Ken, Suhara, Katsuko, Sakaguchi, Masao, Mihara, Katsuyoshi, Omura, Tsuneo
A proline-rich region is present following the signal-anchor sequence in the amino-terminal portion of all known microsomal cytochrome P-450s. To assess the functional significance of the proline...
Failure Mechanisms That Cause High Electrical Leakage in Multilayer Ceramic Capacitors (1981)
Hirofumi Ikeo, Sanpei Sakamoto, Ken Sato, Hisakazu Nishiura, Katsuhiro Ohno
The causes of failure mechanisms of multilayer ceramic capacitors that result in zero resistance (shorts) or low resistance (high leakage) behaviour in the capacitors when the capacitors are...
Rer1p as common machinery for the endoplasmic reticulum localization of membrane proteins
Sato, Ken, Sato, Miyuki, Nakano, Akihiko
Rer1p, a Golgi membrane protein, is required for the correct localization of an endoplasmic reticulum (ER) membrane protein, Sec12p, by a retrieval mechanism from the cis-Golgi to the ER. To test...
Identification of Potential Regulatory Elements for the Transport of Emp24p
Nakamura, Nobuhiro, Yamazaki, Soh, Sato, Ken, Nakano, Akihiko, Sakaguchi, Masao, Mihara, Katsuyoshi
To examine the possibility of active recycling of Emp24p between the endoplasmic reticulum (ER) and the Golgi, we sought to identify transport signal(s) in the carboxyl-terminal region of Emp24p....
Multiple Roles of Arf1 GTPase in the Yeast Exocytic and Endocytic Pathways
Yahara, Natsuko, Ueda, Takashi, Sato, Ken, Nakano, Akihiko
ADP-ribosylation factors, a family of small GTPases, are believed to be key regulators of intracellular membrane traffic. However, many biochemical in vitro experiments have led to different models...
Sato, Miyuki, Sato, Ken, Nishikawa, Shuh-ichi, Hirata, Aiko, Kato, Jun-ichi, Nakano, Akihiko
As an approach to understand the molecular mechanisms of endoplasmic reticulum (ER) protein sorting, we have isolated yeast rer mutants that mislocalize a Sec12-Mfα1p fusion protein from the ER to...
Yorimitsu, Tomohiro, Sato, Ken, Asai, Yukako, Kawagishi, Ikuro, Homma, Michio
Four proteins, PomA, PomB, MotX, and MotY, appear to be involved in force generation of the sodium-driven polar flagella of Vibrio alginolyticus. Among these, PomA and PomB seem to be associated and...
The yeast open reading frame YLR080w/EMP46 encodes a homolog of the Golgi protein Emp47p. These two proteins are 45% identical and have a single transmembrane domain in their C-terminal regions and a...
Zang, Heesuk, Sato, Ken, Nakajima, Hideaki, McKay, Catriona, Ney, Paul A., Ihle, James N.
The erythropoietin receptor (EpoR) is required for the proliferation and survival of committed erythroid lineage cells. Previous studies have utilized receptor mutations to show the requirement for...
Oligomerization of a Cargo Receptor Directs Protein Sorting into COPII-coated Transport Vesicles
Secretory proteins are transported from the endoplasmic reticulum (ER) to the Golgi complex in vesicles coated with coat protein complex II (COPII). The incorporation of certain transport molecules...
Sato, Ken, Sato, Miyuki, Nakano, Akihiko
The yeast Golgi membrane protein Rer1p is required for the retrieval of various endoplasmic reticulum (ER) membrane proteins such as Sec12p and Sec71p to the ER. We demonstrate here that the...
Sato, Miyuki, Sato, Ken, Nakano, Akihiko
Endoplasmic reticulum (ER) quality control is a conserved process by which misfolded or unassembled proteins are selectively retained in the endoplasmic reticulum (ER). Failure in oligomerization of...
A phage display selection of engrailed homeodomain mutants and the importance of residue Q50
Simon, Matthew D., Sato, Ken, Weiss, Gregory A., Shokat, Kevan M.
Mutants of engrailed homeodomain (HD) that retain DNA-binding activity were isolated using a phage display selection. This selection was used to enrich for active DNA-binding clones from a complex...
Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck
Olszewski, Allison, Sato, Ken, Aron, Zachary D., Cohen, Frederick, Harris, Aleishia, McDougall, Brenda R., ...
With current anti-HIV treatments targeting only 4 of the 15 HIV proteins, many potential viral vulnerabilities remain unexploited. We report small-molecule inhibitors of the HIV-1 protein Nef. In...
Caenorhabditis elegans RME-6, a novel regulator of Rab5 at the clathrin-coated pit
Sato, Miyuki, Sato, Ken, Fonarev, Paul, Huang, Chih-Jen, Liou, Willisa, Grant, Barth D.
Using C. elegans genetics we identified a new regulator of endocytosis called RME-6. RME-6 is evolutionarily conserved among metazoans and contains RasGAP-like and Vsp9 domains. Consistent with the...
Dynamic Regulation of Caveolin-1 Trafficking in the Germ Line and Embryo of Caenorhabditis elegans
Sato, Ken, Sato, Miyuki, Audhya, Anjon, Oegema, Karen, Schweinsberg, Peter, Grant, Barth D.
Caveolin is the major protein component required for the formation of caveolae on the plasma membrane. Here we show that trafficking of Caenorhabditis elegans caveolin-1 (CAV-1) is dynamically...
Kosone, Takashi, Takagi, Hitoshi, Kakizaki, Satoru, Sohara, Naondo, Horiguchi, Norio, Sato, Ken, ...
Rer1p as common machinery for the endoplasmic reticulum localization of membrane proteins
Sato, Ken, Sato, Miyuki, Nakano, Akihiko
Rer1p, a Golgi membrane protein, is required for the correct localization of an endoplasmic reticulum (ER) membrane protein, Sec12p, by a retrieval mechanism from the cis-Golgi to the ER. To test...
Identification of Potential Regulatory Elements for the Transport of Emp24p
Nakamura, Nobuhiro, Yamazaki, Soh, Sato, Ken, Nakano, Akihiko, Sakaguchi, Masao, Mihara, Katsuyoshi
To examine the possibility of active recycling of Emp24p between the endoplasmic reticulum (ER) and the Golgi, we sought to identify transport signal(s) in the carboxyl-terminal region of Emp24p....
Multiple Roles of Arf1 GTPase in the Yeast Exocytic and Endocytic Pathways
Yahara, Natsuko, Ueda, Takashi, Sato, Ken, Nakano, Akihiko
ADP-ribosylation factors, a family of small GTPases, are believed to be key regulators of intracellular membrane traffic. However, many biochemical in vitro experiments have led to different models...
Sato, Miyuki, Sato, Ken, Nishikawa, Shuh-ichi, Hirata, Aiko, Kato, Jun-ichi, Nakano, Akihiko
As an approach to understand the molecular mechanisms of endoplasmic reticulum (ER) protein sorting, we have isolated yeast rer mutants that mislocalize a Sec12-Mfα1p fusion protein from the ER to...
Yorimitsu, Tomohiro, Sato, Ken, Asai, Yukako, Kawagishi, Ikuro, Homma, Michio
Four proteins, PomA, PomB, MotX, and MotY, appear to be involved in force generation of the sodium-driven polar flagella of Vibrio alginolyticus. Among these, PomA and PomB seem to be associated and...
The yeast open reading frame YLR080w/EMP46 encodes a homolog of the Golgi protein Emp47p. These two proteins are 45% identical and have a single transmembrane domain in their C-terminal regions and a...
Zang, Heesuk, Sato, Ken, Nakajima, Hideaki, McKay, Catriona, Ney, Paul A., Ihle, James N.
The erythropoietin receptor (EpoR) is required for the proliferation and survival of committed erythroid lineage cells. Previous studies have utilized receptor mutations to show the requirement for...
Oligomerization of a Cargo Receptor Directs Protein Sorting into COPII-coated Transport Vesicles
Secretory proteins are transported from the endoplasmic reticulum (ER) to the Golgi complex in vesicles coated with coat protein complex II (COPII). The incorporation of certain transport molecules...
Sato, Ken, Sato, Miyuki, Nakano, Akihiko
The yeast Golgi membrane protein Rer1p is required for the retrieval of various endoplasmic reticulum (ER) membrane proteins such as Sec12p and Sec71p to the ER. We demonstrate here that the...
Sato, Miyuki, Sato, Ken, Nakano, Akihiko
Endoplasmic reticulum (ER) quality control is a conserved process by which misfolded or unassembled proteins are selectively retained in the endoplasmic reticulum (ER). Failure in oligomerization of...
A phage display selection of engrailed homeodomain mutants and the importance of residue Q50
Simon, Matthew D., Sato, Ken, Weiss, Gregory A., Shokat, Kevan M.
Mutants of engrailed homeodomain (HD) that retain DNA-binding activity were isolated using a phage display selection. This selection was used to enrich for active DNA-binding clones from a complex...
Guanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck
Olszewski, Allison, Sato, Ken, Aron, Zachary D., Cohen, Frederick, Harris, Aleishia, McDougall, Brenda R., ...
With current anti-HIV treatments targeting only 4 of the 15 HIV proteins, many potential viral vulnerabilities remain unexploited. We report small-molecule inhibitors of the HIV-1 protein Nef. In...
Dynamic Regulation of Caveolin-1 Trafficking in the Germ Line and Embryo of Caenorhabditis elegans
Sato, Ken, Sato, Miyuki, Audhya, Anjon, Oegema, Karen, Schweinsberg, Peter, Grant, Barth D.
Caveolin is the major protein component required for the formation of caveolae on the plasma membrane. Here we show that trafficking of Caenorhabditis elegans caveolin-1 (CAV-1) is dynamically...
Kosone, Takashi, Takagi, Hitoshi, Kakizaki, Satoru, Sohara, Naondo, Horiguchi, Norio, Sato, Ken, ...
Smy2p Participates in COPII Vesicle Formation Through the Interaction with Sec23p/Sec24p Subcomplex
Higashio, Hironori, Sato, Ken, Nakano, Akihiko
The coat protein complex II (COPII) is essential for vesicle formation from the endoplasmic reticulum (ER) and is composed of two heterodimeric subcomplexes, Sec23p/Sec24p and Sec13p/Sec31p, and the...
Sato, Ken, Sato, Miyuki, Nakano, Akihiko
Rer1p, a yeast Golgi membrane protein, is required for the retrieval of a set of endoplasmic reticulum (ER) membrane proteins. We present the first evidence that Rer1p directly interacts with the...
Goh, Tatsuaki, Uchida, Wakana, Arakawa, Satoko, Ito, Emi, Dainobu, Tomoko, Ebine, Kazuo, ...
Rab5, a subfamily of Rab GTPases, regulates a variety of endosomal functions as a molecular switch. Arabidopsis thaliana has two different types of Rab5-member GTPases: conventional type, ARA7 and...
Regulation of endocytic recycling by C. elegans Rab35 and its regulator RME-4, a coated-pit protein
Sato, Miyuki, Sato, Ken, Liou, Willisa, Pant, Saumya, Harada, Akihiro, Grant, Barth D
Using Caenorhabditis elegans genetic screens, we identified receptor-mediated endocytosis (RME)-4 and RME-5/RAB-35 as important regulators of yolk endocytosis in vivo. In rme-4 and rab-35 mutants,...
Sato, Ken, Ernstrom, Glen G., Watanabe, Shigeki, Weimer, Robby M., Chen, Chih-Hsiung, Sato, Miyuki, ...
Clathrin is a coat protein involved in vesicle budding from several membrane-bound compartments within the cell. Here we present an analysis of a temperature-sensitive (ts) mutant of clathrin heavy...
Small-cell carcinoma of the extrahepatic bile duct: a case report and review of the literature
Hosonuma, Kenichi, Sato, Ken, Honma, Manabu, Kashiwabara, Kenji, Takahashi, Hitomi, Takagi, Hitoshi, ...
A small-cell carcinoma of the extrahepatic bile duct in a 69-year-old woman is herein reported. A tumor measuring approximately 3 cm in diameter was located at the confluence of the common bile...