Immune defects in Alzheimer's disease: new medications development (2008)
Cashman, John R, Ghirmai, Senait, Abel, Kenneth J, Fiala, Milan
Abstract Alzheimer's disease (AD) is a neurodegenerative disease characterized by the accumulation of intracellular and extracellular aggregates. According to the amyloid beta (Aβ) hypothesis,...
Using DNA pools for genotyping trios (2006)
Beckman, Kenneth B., Abel, Kenneth J., Braun, Andreas, Halperin, Eran
The genotyping of mother–father–child trios is a very useful tool in disease association studies, as trios eliminate population stratification effects and increase the accuracy of haplotype...
Using DNA pools for genotyping trios (2006)
Beckman, Kenneth B., Abel, Kenneth J., Braun, Andreas, Halperin, Eran
The genotyping of mother–father–child trios is a very useful tool in disease association studies, as trios eliminate population stratification effects and increase the accuracy of haplotype...
Using DNA pools for genotyping trios (2006)
Beckman, Kenneth B., Abel, Kenneth J., Braun, Andreas, Halperin, Eran
The genotyping of mother–father–child trios is a very useful tool in disease association studies, as trios eliminate population stratification effects and increase the accuracy of haplotype...
Collins, Francis S., Boehnke, Michael, Chandrasekharappa, Settara C., Shearon, Tempie H., Ho, Peggy P., Couch, Fergus J., ...
The human homolog of the Saccharomyces cerevisiae cell division control 27 gene (CDC27) was mapped to human chromosome 17q12-q21 using a panel of human/rodent somatic cell hybrids and localized...
Microdissection and microcloning of chromosomal alterations in human breast cancer (1995)
Collins, Francis S., Diamond, Austin, Guan, X. Y., Trent, Jeffrey M., Weber, Barbara L., Zhang, Ji, ...
The recognition of recurring sites of chromosome changes in malignancies has greatly facilitated the identification of genes implicated in the pathogenesis of human cancers. Based especially upon...
Transcript identification in the BRCA1 candidate region (1995)
Abel, Kenneth J., Couch, Fergus J., Merajver, Sofia D., Castilla, Lucio H., Brody, Lawrence C., Collins, Francis S., ...
Chromosome 17q12-21 is known to contain a gene (or genes) which confers susceptibility to early-onset breast cancer and ovarian cancer (BRCA1). Identification and isolation of BRCA1 will likely...
Abel, Kenneth J., Xu, Junzhe, Yin, Gui-Ying, Lyons, Robert H., Meisler, Miriam H., Weber, Barbara L.
The human gene BRCA1, conferring susceptibility to early-onset breast and ovarian cancer, has recently been isolated. Here we describe isolation of cDNAs, sequence analysis, and genomic localization...
Couch, Fergus J., Abel, Kenneth J., Brody, Lawrence C., Boehnke, Michael, Collins, Francis S., Weber, Barbara L.
The gene encoding ATP-citrate lyase, designated ACLY, was mapped to human chromosome 17q12-q21 by PCR on a panel of human/rodent somatic cell hybrids and localized to 17q21.1 by PCH on a panel of...
A Radiation Hybrid Map of the BRCA1 Region of Chromosome 17q12-q21 (1993)
Abel, Kenneth J., Boehnke, Michael, Prahalad, Murali, Ho, Peggy P., Flejter, Wendy L., Watkins, Melanie, ...
The chromosomal region 17q12-q21 contains a gene (BRCA1) conferring susceptibility to early-onset familial breast and ovarian cancer. An 8000-rad radiation-reduced hybrid (RH) panel was constructed...
DNA insertions distinguish the duplicated renin genes of DBA/2 and M. hortulanus mice (1991)
Abel, Kenneth J., Howles, Philip N., Gross, Kenneth W.
In a survey of inbred and wild mouse DNAs for genetic variation at the duplicate renin loci, Ren-1 and Ren-2 , a variant Not I hybridization pattern was observed in the wild mouse M. hortulanus . To...
Photocopy of typescript.
Close physical linkage of the murine Ren-1 and Ren-2 loci (1988)
Abel, Kenneth J., Gross, Kenneth W.
In addition to the Ren-1 gene common to all mice, some inbred strains carry a second copy of the renin structural gene, Ren-2. These two loci are tightly linked genetically on mouse chromosome one....
Using DNA pools for genotyping trios
Beckman, Kenneth B., Abel, Kenneth J., Braun, Andreas, Halperin, Eran
The genotyping of mother–father–child trios is a very useful tool in disease association studies, as trios eliminate population stratification effects and increase the accuracy of haplotype...
Using DNA pools for genotyping trios
Beckman, Kenneth B., Abel, Kenneth J., Braun, Andreas, Halperin, Eran
The genotyping of mother–father–child trios is a very useful tool in disease association studies, as trios eliminate population stratification effects and increase the accuracy of haplotype...
Immune defects in Alzheimer's disease: new medications development
Cashman, John R, Ghirmai, Senait, Abel, Kenneth J, Fiala, Milan
Alzheimer's disease (AD) is a neurodegenerative disease characterized by the accumulation of intracellular and extracellular aggregates. According to the amyloid beta (Aβ) hypothesis, amyloidosis...