Bekaii-Saab, Tanios S., Mortazavi, Amir, Hicks, Lee G., Zalupski, Mark M., Pelley, Robert J., Chan, Kenneth K., ...
Purpose: Phase II multicenter study investigated the efficacy and toxicity of the novel halogenated derivative of sulfaquixonaline Chloroquinoxaline Sulfonamide (CQS) in metastatic colorectal cancer....
Design of the HP PA 7200 CPU (2002)
Kenneth K. Chan, Cyrus C. Hay, John R. Keller, Gordon P. Kurpanek, Francis X. Schumacher, Jason Zheng
l cache arrays. This includes integer and floating-point execution units, a 120-entry fully associative translation lookaside buffer (TLB) with 16-block translation entries and hardware TLB miss...
Thesis (M.S. in Engineering)--University of California, Berkeley, Dec. 1987.
Servis, Kenneth L., Valente, Edward J., Chan, Kenneth K.
The proposed tautomeric equilibrium between the microsomal metabolite of cyclophosphamide, 4-hydroxycyclophosphamide, and the open chain aldophosphamide, and the subsequent facile β-elimination to...
Giannini, Donald D., Chan, Kenneth K., Roberts, John D.
Carbon-13 nuclear magnetic resonance spectra have been obtained for the coumarin-related compounds warfarin and phenprocoumon. The spectral assignments indicate that warfarin exists as a mixture of...
XK469, a selective topoisomerase IIβ poison
Gao, Hanlin, Huang, Kuan-Chun, Yamasaki, Edith F., Chan, Kenneth K., Chohan, Lubna, Snapka, Robert M.
XK469 (NSC 697887) is a synthetic quinoxaline phenoxypropionic acid derivative that possesses unusual solid tumor selectivity and activity against multidrug-resistant cancer cells. We report here...
Warfarin STEREOCHEMICAL ASPECTS OF ITS METABOLISM AND THE INTERACTION WITH PHENYLBUTAZONE
Lewis, Richard J., Trager, William F., Chan, Kenneth K., Breckenridge, A., Orme, M., Roland, Malcolm, ...
An examination of the metabolic fate of the R and the S isomers of warfarin revealed that the two isomers were metabolized by different routes. R warfarin was oxidized to 6-hydroxywarfarin and was...
Giannini, Donald D., Chan, Kenneth K., Roberts, John D.
Carbon-13 nuclear magnetic resonance spectra have been obtained for the coumarin-related compounds warfarin and phenprocoumon. The spectral assignments indicate that warfarin exists as a mixture of...
XK469, a selective topoisomerase IIβ poison
Gao, Hanlin, Huang, Kuan-Chun, Yamasaki, Edith F., Chan, Kenneth K., Chohan, Lubna, Snapka, Robert M.
XK469 (NSC 697887) is a synthetic quinoxaline phenoxypropionic acid derivative that possesses unusual solid tumor selectivity and activity against multidrug-resistant cancer cells. We report here...
Warfarin STEREOCHEMICAL ASPECTS OF ITS METABOLISM AND THE INTERACTION WITH PHENYLBUTAZONE
Lewis, Richard J., Trager, William F., Chan, Kenneth K., Breckenridge, A., Orme, M., Roland, Malcolm, ...
An examination of the metabolic fate of the R and the S isomers of warfarin revealed that the two isomers were metabolized by different routes. R warfarin was oxidized to 6-hydroxywarfarin and was...
Giannini, Donald D., Chan, Kenneth K., Roberts, John D.
Carbon-13 nuclear magnetic resonance spectra have been obtained for the coumarin-related compounds warfarin and phenprocoumon. The spectral assignments indicate that warfarin exists as a mixture of...
Liu, Zhongfa, Liu, Shujun, Xie, Zhiliang, Blum, William, Perrotti, Danilo, Paschka, Peter, ...
DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents (e.g., decitabine). Detection of changes in DNA methylation might...
Fabbri, Muller, Garzon, Ramiro, Cimmino, Amelia, Liu, Zhongfa, Zanesi, Nicola, Callegari, Elisa, ...
MicroRNAs (miRNAs) are small, noncoding RNAs that regulate expression of many genes. Recent studies suggest roles of miRNAs in carcinogenesis. We and others have shown that expression profiles of...