Ki A. Goosens

NMDA receptors are essential for the acquisition, but not expression, of conditional fear and associative spike firing in the lateral amygdala (2004)

Goosens, Ki A., Maren, Stephen

We examined the contribution of N-methyl-D-aspartate (NMDA) receptors (NMDARs) to the acquisition and expression of amygdaloid plasticity and Pavlovian fear conditioning using single-unit recording...

Auditory-evoked spike firing in the lateral amygdala and Pavlovian fear conditioning: mnemonic code or fear bias? (2003)

Goosens, Ki A., Hobin, Jennifer A., Maren, Stephen

Amygdala neuroplasticity has emerged as a candidate substrate for Pavlovian fear memory. By this view, conditional stimulus (CS)-evoked activity represents a mnemonic code that initiates the...

Context-dependent neuronal activity in the lateral amygdala represents fear memories after extinction (2003)

Hobin, Jennifer A., Goosens, Ki A., Maren, Stephen

The context in which fear memories are extinguished has important implications for treating human fear and anxiety disorders. Extinction of Pavlovian fear conditioning is context specific; after...

Pretraining NMDA receptor blockade in the basolateral complex, but not the central nucleus, of the amygdala prevents savings of conditional fear (2003)

Goosens, Ki A., Maren, Stephen

The acquisition of conditional freezing is abolished by N-methyl-D-aspartate (NMDA) receptor antagonism in the basolateral complex of the amygdala (BLA) during fear conditioning, suggesting that...

Conditional plasticity in the amygdala : substrates, molecular mechanisms, and the relationship to fear behavior. (2002)

Goosens, Ki A.

Dissertation (Ph.D.)--University of Michigan.

Long-term potentiation as a substrate for memory: evidence from studies of amygdaloid plasticity and Pavlovian fear conditioning (2002)

Goosens, Ki A., Maren, Stephen

Recent reports have raised concerns about the ability of long-term potentiation (LTP) to account for associative learning and memory. In this paper, we review the many mechanistic similarities...

Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in rats (2001)

Goosens, Ki A.

A large body of literature implicates the amygdala in Pavlovian fear conditioning. In this study, we examined the contribution of individual amygdaloid nuclei to contextual and auditory fear...

The amygdala is essential for the development of neuronal plasticity in the medial geniculate nucleus during auditory fear conditioning in rats (2001)

Maren, Stephen, Yap, Stanley A., Goosens, Ki A.

The medial geniculate nucleus of the thalamus (MGN) and the basolateral complex of the amygdala (BLA) are critical components of the neural circuit that mediates auditory fear conditioning. Several...

Contextual and Auditory Fear Conditioning are Mediated by the Lateral, Basal, and Central Amygdaloid Nuclei in Rats (2001)

Goosens, Ki A., Maren, Stephen

A role for amygdaloid PKA and PKC in the acquisition of long-term conditional fear memories in rats (2000)

Goosens, Ki A., Holt, William, Maren, Stephen

Although there is great interest in the cellular mechanisms underlying Pavlovian conditioning, few studies have directly examined the contribution of intracellular signaling pathways in the amygdala...

Alterations in size, number, and morphology of gustatory papillae and taste buds in BDNF null mutant mice demonstrate neural dependence of developing taste organs (1999)

Mistretta, Charlotte M., Goosens, Ki A., Farinas, Isabel, Reichardt, Louis F.

Sensory ganglia that innervate taste buds and gustatory papillae (geniculate and petrosal) are reduced in volume by about 40% in mice with a targeted deletion of the gene for brain-derived...

Contextual and Auditory Fear Conditioning are Mediated by the Lateral, Basal, and Central Amygdaloid Nuclei in Rats

Goosens, Ki A., Maren, Stephen

A large body of literature implicates the amygdala in Pavlovian fear conditioning. In this study, we examined the contribution of individual amygdaloid nuclei to contextual and auditory fear...

Contextual and Auditory Fear Conditioning are Mediated by the Lateral, Basal, and Central Amygdaloid Nuclei in Rats

Goosens, Ki A., Maren, Stephen

A large body of literature implicates the amygdala in Pavlovian fear conditioning. In this study, we examined the contribution of individual amygdaloid nuclei to contextual and auditory fear...