Kiichi Watanabe

Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity

Kawasaki, Hiroshi, Suemori, Hirofumi, Mizuseki, Kenji, Watanabe, Kiichi, Urano, Fumi, Ichinose, Hiroshi, ...

We previously identified a stromal cell-derived inducing activity (SDIA), which induces differentiation of neural cells, including midbrain tyrosine hydroxylase-positive (TH+) dopaminergic neurons,...

Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells

Mizuseki, Kenji, Sakamoto, Tatsunori, Watanabe, Kiichi, Muguruma, Keiko, Ikeya, Makoto, Nishiyama, Ayaka, ...

To understand the range of competence of embryonic stem (ES) cell-derived neural precursors, we have examined in vitro differentiation of mouse and primate ES cells into the dorsal- (neural crest)...

Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells

Ikeda, Hanako, Osakada, Fumitaka, Watanabe, Kiichi, Mizuseki, Kenji, Haraguchi, Tomoko, Miyoshi, Hiroyuki, ...

We report directed differentiaion of retinal precursors in vitro from mouse ES cells. Six3+ rostral brain progenitors are generated by culturing ES cells under serum-free suspension conditions (SFEB...

Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix

Ueno, Morio, Matsumura, Michiru, Watanabe, Kiichi, Nakamura, Takahiro, Osakada, Fumitaka, Takahashi, Masayo, ...

Here we report a human-derived material with potent inductive activity that selectively converts ES cells into neural tissues. Both mouse and human ES cells efficiently differentiate into neural...

Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity

Kawasaki, Hiroshi, Suemori, Hirofumi, Mizuseki, Kenji, Watanabe, Kiichi, Urano, Fumi, Ichinose, Hiroshi, ...

We previously identified a stromal cell-derived inducing activity (SDIA), which induces differentiation of neural cells, including midbrain tyrosine hydroxylase-positive (TH+) dopaminergic neurons,...

Generation of neural crest-derived peripheral neurons and floor plate cells from mouse and primate embryonic stem cells

Mizuseki, Kenji, Sakamoto, Tatsunori, Watanabe, Kiichi, Muguruma, Keiko, Ikeya, Makoto, Nishiyama, Ayaka, ...

To understand the range of competence of embryonic stem (ES) cell-derived neural precursors, we have examined in vitro differentiation of mouse and primate ES cells into the dorsal- (neural crest)...

Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells

Ikeda, Hanako, Osakada, Fumitaka, Watanabe, Kiichi, Mizuseki, Kenji, Haraguchi, Tomoko, Miyoshi, Hiroyuki, ...

We report directed differentiaion of retinal precursors in vitro from mouse ES cells. Six3+ rostral brain progenitors are generated by culturing ES cells under serum-free suspension conditions (SFEB...

Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation

Wataya, Takafumi, Ando, Satoshi, Muguruma, Keiko, Ikeda, Hanako, Watanabe, Kiichi, Eiraku, Mototsugu, ...

Embryonic stem (ES) cells differentiate into neuroectodermal progenitors when cultured as floating aggregates in serum-free conditions. Here, we show that strict removal of exogenous patterning...