Kim C. Worley

Unlocking the bovine genome (2009)

Tellam, Ross L, Lemay, Danielle G, Van Tassell, Curtis P, Lewin, Harris A, Worley, Kim C, Elsik, Christine G

Abstract The draft genome sequence of cattle ( Bos taurus ) has now been analyzed by the Bovine Genome Sequencing and Analysis Consortium and the Bovine HapMap Consortium, which together represent an...

Bos taurusgenome assembly (2009)

Liu, Yue, Qin, Xiang, Song, Xing-Zhi, Jiang, Huaiyang, Shen, Yufeng, Durbin, K James, ...

Abstract Background We present here the assembly of the bovine genome. The assembly method combines the BAC plus WGS local assembly used for the rat and sea urchin with the whole genome shotgun (WGS)...

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome (2007)

Margulies, Elliott H., Cooper, Gregory M., Asimenos, George, Thomas, Daryl J., Dewey, Colin N., Siepel, Adam, ...

A key component of the ongoing ENCODE project involves rigorous comparative sequence analyses for the initially targeted 1% of the human genome. Here, we present orthologous sequence generation,...

The genome of Apis mellifera: dialog between linkage mapping and sequence assembly (2007)

Solignac, Michel, Zhang, Lan, Mougel, Florence, Li, Bingshan, Vautrin, Dominique, Monnerot, Monique, ...

Abstract Two independent genome projects for the honey bee, a microsatellite linkage map and a genome sequence assembly, interactively produced an almost complete organization of the euchromatic...

Insights into social insects from the genome of the honeybee Apis mellifera (2006)

Robinson, Gene E, Gibbs, Richard A, Worley, Kim C, Evans, Jay D, Maleszka, Ryszard, ...

Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes,...

Community annotation: Procedures, protocols, and supporting tools (2006)

Elsik, Christine G., Worley, Kim C., Zhang, Lan, Milshina, Natalia V., Jiang, Huaiyang, Reese, Justin T., ...

Investigators at the Baylor College of Medicine Human Genome Sequencing Center (BCM–HGSC) and BeeBase organized a community-wide effort to manually annotate the honey bee (Apis mellifera) genome....

Community annotation: Procedures, protocols, and supporting tools (2006)

Elsik, Christine G., Worley, Kim C., Zhang, Lan, Milshina, Natalia V., Jiang, Huaiyang, Reese, Justin T., ...

Investigators at the Baylor College of Medicine Human Genome Sequencing Center (BCM–HGSC) and BeeBase organized a community-wide effort to manually annotate the honey bee (Apis mellifera) genome....

Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution (2005)

Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...

We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout...

Comparative genome sequencing of drosophila pseudoobscura: Chromosomal, gene and cis-element evolution (2004)

Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...

The genome sequence of a second fruit fly, D. pseudoobscura, presents an opportunity for comparative analysis of a primary model organism D. melanogaster. The vast majority of Drosophila genes have...

A computational/functional genomics approach for the enrichment of the retinal transcriptome and the identification of positional candidate retinopathy genes

Katsanis, Nicholas, Worley, Kim C., Gonzalez, Guillermo, Ansley, Stephen J., Lupski, James R.

Grouping genes by virtue of their sequence similarity, functional association, or spatiotemporal distribution is an important first step in investigating function. Given the recent identification of...

Large-Scale Concatenation cDNA Sequencing

Yu, Wei, Andersson, Björn, Worley, Kim C., Muzny, Donna M., Ding, Yan, Liu, Wen, ...

A total of 100 kb of DNA derived from 69 individual human brain cDNA clones of 0.7–2.0 kb were sequenced by concatenated cDNA sequencing (CCS), whereby multiple individual DNA fragments are...

Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution

Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...

We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout...

A computational/functional genomics approach for the enrichment of the retinal transcriptome and the identification of positional candidate retinopathy genes

Katsanis, Nicholas, Worley, Kim C., Gonzalez, Guillermo, Ansley, Stephen J., Lupski, James R.

Grouping genes by virtue of their sequence similarity, functional association, or spatiotemporal distribution is an important first step in investigating function. Given the recent identification of...

Large-Scale Concatenation cDNA Sequencing

Yu, Wei, Andersson, Björn, Worley, Kim C., Muzny, Donna M., Ding, Yan, Liu, Wen, ...

A total of 100 kb of DNA derived from 69 individual human brain cDNA clones of 0.7–2.0 kb were sequenced by concatenated cDNA sequencing (CCS), whereby multiple individual DNA fragments are...

Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution

Richards, Stephen, Liu, Yue, Bettencourt, Brian R., Hradecky, Pavel, Letovsky, Stan, Nielsen, Rasmus, ...

We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout...

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

Margulies, Elliott H., Cooper, Gregory M., Asimenos, George, Thomas, Daryl J., Dewey, Colin N., Siepel, Adam, ...

A key component of the ongoing ENCODE project involves rigorous comparative sequence analyses for the initially targeted 1% of the human genome. Here, we present orthologous sequence generation,...

Unlocking the bovine genome

Tellam, Ross L, Lemay, Danielle G, Van Tassell, Curtis P, Lewin, Harris A, Worley, Kim C, Elsik, Christine G

The draft genome sequence of cattle (Bos taurus) has now been analyzed by the Bovine Genome Sequencing and Analysis Consortium and the Bovine HapMap Consortium, which together represent an extensive...