Kim Nichols

Publication List Details

Period

2001 - 2006

Number

11

Co-Authors

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing (2006)

Jackson, Aimee L., Burchard, Julja, Leake, Devin, Reynolds, Angela, Schelter, Janell, Guo, Jie, ...

Transfected siRNAs regulate numerous transcripts sharing limited complementarity to the RNA duplex. This unintended (“off-target”) silencing can hinder the use of RNAi to define gene function....

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing (2006)

Jackson, Aimee L., Burchard, Julja, Leake, Devin, Reynolds, Angela, Schelter, Janell, Guo, Jie, ...

Transfected siRNAs regulate numerous transcripts sharing limited complementarity to the RNA duplex. This unintended (“off-target”) silencing can hinder the use of RNAi to define gene function....

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing (2006)

Jackson, Aimee L., Burchard, Julja, Leake, Devin, Reynolds, Angela, Schelter, Janell, Guo, Jie, ...

Transfected siRNAs regulate numerous transcripts sharing limited complementarity to the RNA duplex. This unintended (“off-target”) silencing can hinder the use of RNAi to define gene function....

Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing

Jackson, Aimee L., Burchard, Julja, Leake, Devin, Reynolds, Angela, Schelter, Janell, Guo, Jie, ...

Transfected siRNAs regulate numerous transcripts sharing limited complementarity to the RNA duplex. This unintended (“off-target”) silencing can hinder the use of RNAi to define gene function....

Neural mechanisms underlying migrating motor complex formation in mouse isolated colon

Brierley, Stuart M, Nichols, Kim, Grasby, Dallas J, Waterman, Sally A

Little is known about the intrinsic enteric reflex pathways associated with migrating motor complex (MMC) formation. Acetylcholine (ACh) mediates the rapid component of the MMC, however a...