Kirsty Holmgren

Age-associated shifts in cardiac gene transcription and transcriptional responses to ischemic stress (2006)

Ashton, Kevin John, Willems, Laura, Holmgren, Kirsty, Ferreira, Linda Anne, Headrick, John Patrick

Aged hearts exhibit reduced tolerance to ischemia-reperfusion, together with altered structure and post-ischemic remodelling. The molecular bases of such changes are unclear. Using cDNA microarrays...

Age-associated shifts in cardiac gene transcription and transcriptional responses to ischemic stress (2006)

Ashton, Kevin John, Willems, Laura, Holmgren, Kirsty, Ferreira, Linda Anne, Headrick, John Patrick

Aged hearts exhibit reduced tolerance to ischemia-reperfusion, together with altered structure and post-ischemic remodelling. The molecular bases of such changes are unclear. Using cDNA microarrays...

Age-associated shifts in cardiac gene transcription and transcriptional responses to ischemic stress (2006)

Ashton, Kevin John, Willems, Laura, Holmgren, Kirsty, Ferreira, Linda Anne, Headrick, John Patrick

Aged hearts exhibit reduced tolerance to ischemia-reperfusion, together with altered structure and post-ischemic remodelling. The molecular bases of such changes are unclear. Using cDNA microarrays...

Age-associated shifts in cardiac gene transcription and transcriptional responses to ischemic stress (2006)

Ashton, Kevin John, Willems, Laura, Holmgren, Kirsty, Ferreira, Linda Anne, Headrick, John Patrick

Aged hearts exhibit reduced tolerance to ischemia-reperfusion, together with altered structure and post-ischemic remodelling. The molecular bases of such changes are unclear. Using cDNA microarrays...

Effects of A1 adenosine receptor overexpression on normoxic and post-ischemic gene expression (2003)

Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Lankford, Amy R., Matherne, G. Paul, Grimmond, Sean, ...

Objectives: To identify potential molecular genetic determinants of cardiovascular ischemic tolerance in wild-type and transgenic hearts overexpressing A1 adenosine receptors (A1ARs). Methods: cDNA...

Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression (2003)

Headrick, John Patrick, Willems, Laura, Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Matherne, G. Paul

The genesis of the ischaemia intolerant phenotype in aged myocardium is poorly understood. We tested the hypothesis that impaired adenosine-mediated protection contributes to ischaemic intolerance,...

Effects of A1 adenosine receptor overexpression on normoxic and post-ischemic gene expression (2003)

Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Lankford, Amy R., Matherne, G. Paul, Grimmond, Sean, ...

Objectives: To identify potential molecular genetic determinants of cardiovascular ischemic tolerance in wild-type and transgenic hearts overexpressing A1 adenosine receptors (A1ARs). Methods: cDNA...

Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression (2003)

Headrick, John Patrick, Willems, Laura, Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Matherne, G. Paul

The genesis of the ischaemia intolerant phenotype in aged myocardium is poorly understood. We tested the hypothesis that impaired adenosine-mediated protection contributes to ischaemic intolerance,...

Effects of A1 adenosine receptor overexpression on normoxic and post-ischemic gene expression (2003)

Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Lankford, Amy R., Matherne, G. Paul, Grimmond, Sean, ...

Objectives: To identify potential molecular genetic determinants of cardiovascular ischemic tolerance in wild-type and transgenic hearts overexpressing A1 adenosine receptors (A1ARs). Methods: cDNA...

Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression (2003)

Headrick, John Patrick, Willems, Laura, Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Matherne, G. Paul

The genesis of the ischaemia intolerant phenotype in aged myocardium is poorly understood. We tested the hypothesis that impaired adenosine-mediated protection contributes to ischaemic intolerance,...

Effects of A1 adenosine receptor overexpression on normoxic and post-ischemic gene expression (2003)

Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Lankford, Amy R., Matherne, G. Paul, Grimmond, Sean, ...

Objectives: To identify potential molecular genetic determinants of cardiovascular ischemic tolerance in wild-type and transgenic hearts overexpressing A1 adenosine receptors (A1ARs). Methods: cDNA...

Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression (2003)

Headrick, John Patrick, Willems, Laura, Ashton, Kevin John, Holmgren, Kirsty, Peart, Jason Nigel John, Matherne, G. Paul

The genesis of the ischaemia intolerant phenotype in aged myocardium is poorly understood. We tested the hypothesis that impaired adenosine-mediated protection contributes to ischaemic intolerance,...

Effects of A1 adenosine receptor overexpression on normoxic and post-ischemic gene expression (2003)

Ashton, Kevin J, Holmgren, Kirsty, Peart, Jason, Lankford, Amy R, Paul Matherne, G, Grimmond, Sean, ...

Objectives: To identify potential molecular genetic determinants of cardiovascular ischemic tolerance in wild-type and transgenic hearts overexpressing A1 adenosine receptors (A1ARs). Methods: cDNA...