Cracking the Enigmatic Linker Histone Code (2008)
Recently, the existence of a ‘histone code’ has been proposed to explain the link between the covalent chemical modification of histone proteins and the epigenetic regulation of gene activity....
Distinct DNA Methylation Activity of Dnmt3a and Dnmt3b towards Naked and Nucleosomal DNA (2006)
Takeshima, Hideyuki, Suetake, Isao, Shimahara, Hideto, Ura, Kiyoe, Tate, Shin-ichi, Tajima, Shoji
In mammals, the resetting of DNA methylation patterns in early embryos and germ cells is crucial for development. De novo type DNA methyltransferases Dnmt3a and Dnmt3b are responsible for creating...
The Hox-2.1 gene is one of homeobox-containing genes located in theHox-2 cluster on mouse chromosome 11. In this study, we have examined transcription of the Hox-2.1 gene during differentiation of F9...
Mizutani, Mitsuko, Ura, Kiyoe, Hirose, Susumu
In vitro transcription was reconstituted with HeLa cell transcription factors and RNA polymerase II, which were essentially free from DNA topoisomerase activities. DNA templates with defined negative...
Ura, Kiyoe, Araki, Marito, Saeki, Hideaki, Masutani, Chikahide, Ito, Takashi, Iwai, Shigenori, ...
To investigate the relationship between chromatin dynamics and nucleotide excision repair (NER), we have examined the effect of chromatin structure on the formation of two major classes of UV-induced...
Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs
Shintomi, Keishi, Iwabuchi, Mari, Saeki, Hideaki, Ura, Kiyoe, Kishimoto, Takeo, Ohsumi, Keita
In eukaryotic cells, genomic DNA is primarily packaged into nucleosomes through sequential ordered binding of the core and linker histone proteins. The acidic proteins termed histone chaperones are...
Ura, Kiyoe, Araki, Marito, Saeki, Hideaki, Masutani, Chikahide, Ito, Takashi, Iwai, Shigenori, ...
To investigate the relationship between chromatin dynamics and nucleotide excision repair (NER), we have examined the effect of chromatin structure on the formation of two major classes of UV-induced...
Linker histone variants control chromatin dynamics during early embryogenesis
Saeki, Hideaki, Ohsumi, Keita, Aihara, Hitoshi, Ito, Takashi, Hirose, Susumu, Ura, Kiyoe, ...
Complex transitions in chromatin structure produce changes in genome function during development in metazoa. Linker histones, the last component of nucleosomes to be assembled into chromatin,...
Nucleosome assembly protein-1 is a linker histone chaperone in Xenopus eggs
Shintomi, Keishi, Iwabuchi, Mari, Saeki, Hideaki, Ura, Kiyoe, Kishimoto, Takeo, Ohsumi, Keita
In eukaryotic cells, genomic DNA is primarily packaged into nucleosomes through sequential ordered binding of the core and linker histone proteins. The acidic proteins termed histone chaperones are...