Klaus Dornmair

CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery (2009)

Schwab, Nicholas, Bien, Christian G., Waschbisch, Anne, Becker, Albert, Vince, Giles H., Dornmair, Klaus, ...

Rasmussen encephalitis (RE) is a rare neurological disorder of childhood characterized by uni-hemispheric inflammation, progressive neurological deficits and intractable focal epilepsy. Destruction...

Multiple sclerosis: T-cell receptor expression in distinct brain regions (2007)

Junker, Andreas, Ivanidze, Jana, Malotka, Joachim, Eiglmeier, Ingrid, Lassmann, Hans, Wekerle, Hartmut, ...

Multiple sclerosis (MS) is an inflammatory demyelinating disease where T cells attack the brain and the spinal cord. It is known that often particular T-cell clones are expanded in the target tissue,...

Reconstitution of paired T cell receptor alpha- and beta-chains from microdissected single cells of human inflammatory tissues (2006)

Seitz, Sabine, Schneider, Christian K., Malotka, Joachim, Nong, Xiao, Engel, A. G., Wekerle, Hartmut, ...

Antigen recognition properties of a V gamma LW delta 2-T-cell receptor from a rare variant of polymyositis (2004)

Dornmair,Klaus, Schneider,Christian K., Malotka,Joachim, Dechant,Georg, Wiendl,Heinz, Hohlfeld,Reinhard

Killing of target cells by redirected granzyme B in the absence of perforin (2004)

Kurschus,Florian C., Kleinschmidt,M., Fellows,Edward, Dornmair,Klaus, Rudolph,R., Lilie,H., ...

Multiple sclerosis: Brain-infiltrating CD8(+) T cells persist as clonal expansions in the cerebrospinal fluid and blood (2004)

Skulina,Christian, Schmidt,Stephan, Dornmair,Klaus, Babbe,Holger, Roers,Axel, Rajewsky,Klaus, ...

Antigen recognition properties of a V gamma LW delta 2-T-cell receptor from a rare variant of polymyositis (2004)

Dornmair, Klaus, Schneider, Christian K., Malotka, Joachim, Dechant, Georg, Wiendl, Heinz, Hohlfeld, Reinhard

Killing of target cells by redirected granzyme B in the absence of perforin (2004)

Kurschus, Florian C., Kleinschmidt, M., Fellows, Edward, Dornmair, Klaus, Rudolph, R., Lilie, H., ...

Multiple sclerosis: Brain-infiltrating CD8(+) T cells persist as clonal expansions in the cerebrospinal fluid and blood (2004)

Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...

T-cell-mediated autoimmunity - Novel techniques to characterize autoreactive T-cell receptors (2003)

Dornmair,Klaus, Goebels,Norbert, Weltzien,H. U., Wekerle,Hartmut, Hohlfeld,Reinhard

Histological samples of autopsy or biopsy tissue provide the best available evidence that autoreactive T cells are involved in the immunopathogenesis of many autoimmune diseases. However, morphology...

Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis (2003)

Hofbauer,Monika, Wiesener,S., Babbe,H., Roers,A., Wekerle,Hartmut, Dornmair,Klaus, ...

Clonal expansions of CD8+ T cells have been identified in muscle and blood of polymyositis patients by PCR techniques, including T cell receptor (TCR) complementarity-determining region (CDR)3 length...

Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis (2003)

Hofbauer, Monika, Wiesener, S., Babbe, H., Roers, A., Wekerle, Hartmut, Dornmair, Klaus, ...

Clonal expansions of CD8+ T cells have been identified in muscle and blood of polymyositis patients by PCR techniques, including T cell receptor (TCR) complementarity-determining region (CDR)3 length...

T-cell-mediated autoimmunity - Novel techniques to characterize autoreactive T-cell receptors (2003)

Dornmair, Klaus, Goebels, Norbert, Weltzien, H. U., Wekerle, Hartmut, Hohlfeld, Reinhard

Histological samples of autopsy or biopsy tissue provide the best available evidence that autoreactive T cells are involved in the immunopathogenesis of many autoimmune diseases. However, morphology...

An autoreactive gamma delta TCR derived from a polymyositis lesion (2002)

Wiendl,Heinz, Malotka,Joachim, Holzwarth,B., Weltzien,H. U., Wekerle,Hartmut, Hohlfeld,Reinhard, ...

To investigate the role of gammadelta T cells in human autoimmune disease we expressed and characterized a gammadelta TCR from an autoimmune tissue lesion. The TCR was first identified in a rare form...

An autoreactive gamma delta TCR derived from a polymyositis lesion (2002)

Wiendl, Heinz, Malotka, Joachim, Holzwarth, B., Weltzien, H. U., Wekerle, Hartmut, Hohlfeld, Reinhard, ...

To investigate the role of gammadelta T cells in human autoimmune disease we expressed and characterized a gammadelta TCR from an autoimmune tissue lesion. The TCR was first identified in a rare form...

Laktose - Permease [microform] : Struktur und Dynamik eines Zuckertransportproteins / (1987)

Dornmair, Klaus.

Thesis (doctoral)--Eberhard-Karls-Universität zu Tübingen, 1987.

Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis

Hofbauer, Monika, Wiesener, Solveigh, Babbe, Holger, Roers, Axel, Wekerle, Hartmut, Dornmair, Klaus, ...

Clonal expansions of CD8+ T cells have been identified in muscle and blood of polymyositis patients by PCR techniques, including T cell receptor (TCR) complementarity-determining region (CDR)3 length...

Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood

Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...

We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to...

Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis

Hofbauer, Monika, Wiesener, Solveigh, Babbe, Holger, Roers, Axel, Wekerle, Hartmut, Dornmair, Klaus, ...

Clonal expansions of CD8+ T cells have been identified in muscle and blood of polymyositis patients by PCR techniques, including T cell receptor (TCR) complementarity-determining region (CDR)3 length...

Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood

Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...

We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to...

Reconstitution of paired T cell receptor α- and β-chains from microdissected single cells of human inflammatory tissues

Seitz, Sabine, Schneider, Christian K., Malotka, Joachim, Nong, Xiao, Engel, Andrew G., Wekerle, Hartmut, ...

We describe a strategy to “revive” putatively pathogenic T cells from frozen specimens of human inflammatory target organs. To distinguish pathogenic from irrelevant bystander T cells, we focused...

T-Cell-Mediated Autoimmunity: Novel Techniques to Characterize Autoreactive T-Cell Receptors

Dornmair, Klaus, Goebels, Norbert, Weltzien, Hans-Ulrich, Wekerle, Hartmut, Hohlfeld, Reinhard

Histological samples of autopsy or biopsy tissue provide the best available evidence that autoreactive T cells are involved in the immunopathogenesis of many autoimmune diseases. However, morphology...

The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons

Deininger, Katrin, Eder, Matthias, Kramer, Edgar R., Zieglgänsberger, Walter, Dodt, Hans-Ulrich, Dornmair, Klaus, ...

Ephrin signaling through Eph receptor tyrosine kinases regulates important morphogenetic events during development and synaptic plasticity in the adult brain. Although Eph-ephrin endocytosis is...

NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist

Dammermann, Werner, Zhang, Bo, Nebel, Merle, Cordiglieri, Chiara, Odoardi, Francesca, Kirchberger, Tanja, ...

The nucleotide NAADP was recently discovered as a second messenger involved in the initiation and propagation of Ca2+ signaling in lymphoma T cells, but its impact on primary T cell function is still...