Tate, Genshu, Suzuki, Takao, Kishimoto, Koji, Mitsuya, Toshiyuki
Mutations of the c-KIT gene have been reported not only in gastrointestinal stromal tumors and mast cell tumors, but also in testicular germ cell tumors (TGCTs). In the present study we employed...
Infertility Observed in Reproductive Toxicity Study of N-Acetyl-l-Cysteine in Rats (2003)
Miwa Harada, Koji Kishimoto, Tadakazu Furuhashi, Kazuyosi Naito, Yoshifumi Nakashima, Yoshiro Kawaguchi, ...
The toxic effects of i.v. administration of N-acetyl-l-cysteine (NAC), a component of parenteral nutrition solutions, on fertility and embryonic development were investigated in SD male and female...
Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance
Kishimoto, Koji, Sandner, Sigrid, Imitola, Jaime, Sho, Masayuki, Li, Yongsheng, Langmuir, Peter B., ...
The Th1 cytokines IL-2 and IFN-γ, which inhibit T cell proliferation and promote activation induced cell death, may be required to diminish alloreactive T cell numbers and to foster tolerance across...
Kishimoto, Koji, Dong, Victor M., Issazadeh, Shohreh, Fedoseyeva, Eugenia V., Waaga, Ana Maria, Yamada, Akira, ...
We used signal transducer and activator of transcription 4 (STAT4) and STAT6 gene knockout (–/–) mice as recipients of fully mismatched cardiac allografts to study the role of T-cell...
Requirements for induction and maintenance of peripheral tolerance in stringent allograft models
Sho, Masayuki, Kishimoto, Koji, Harada, Hiroshi, Livak, Mauren, Sanchez-Fueyo, Alberto, Yamada, Akira, ...
Peripheral tolerance can be achieved in many but not all murine allograft models. The requirements for controlling more aggressive immune responsiveness and generating peripheral tolerance in...
Sho, Masayuki, Sandner, Sigrid E., Najafian, Nader, Salama, Alan D., Dong, Victor, Yamada, Akira, ...
Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance
Kishimoto, Koji, Sandner, Sigrid, Imitola, Jaime, Sho, Masayuki, Li, Yongsheng, Langmuir, Peter B., ...
The Th1 cytokines IL-2 and IFN-γ, which inhibit T cell proliferation and promote activation induced cell death, may be required to diminish alloreactive T cell numbers and to foster tolerance across...
Kishimoto, Koji, Dong, Victor M., Issazadeh, Shohreh, Fedoseyeva, Eugenia V., Waaga, Ana Maria, Yamada, Akira, ...
We used signal transducer and activator of transcription 4 (STAT4) and STAT6 gene knockout (–/–) mice as recipients of fully mismatched cardiac allografts to study the role of T-cell...
Requirements for induction and maintenance of peripheral tolerance in stringent allograft models
Sho, Masayuki, Kishimoto, Koji, Harada, Hiroshi, Livak, Mauren, Sanchez-Fueyo, Alberto, Yamada, Akira, ...
Peripheral tolerance can be achieved in many but not all murine allograft models. The requirements for controlling more aggressive immune responsiveness and generating peripheral tolerance in...
Sho, Masayuki, Sandner, Sigrid E., Najafian, Nader, Salama, Alan D., Dong, Victor, Yamada, Akira, ...
SAWADA, TAKAHIRO, KOJI, TAKEHIKO, HISHIKAWA, YOSHITAKA, KISHIMOTO, KOJI, NAGAYASU, TAKESHI, TAKAHASHI, TAKAO, ...
Certain anti-Fas antibodies, such as RMF2, induce apoptosis of Fas-expressing cells. We applied the Fas/anti-Fas system to induce killing of Fas-expressing immunocytes with resultant...
Yoshioka, Norie, Wang, Li, Kishimoto, Koji, Tsuji, Takanori, Hu, Guo-fu
Human angiogenin is progressively up-regulated in the prostate epithelial cells during the development of prostate cancer from prostate intraepithelial neoplasia (PIN) to invasive adenocarcinoma....
Shen, Ying, Kishimoto, Koji, Linden, David J., Sapirstein, Adam
The arachidonic acid-generating enzyme cytosolic phospholipase A2 alpha (cPLA2α) has been implicated in the progression of excitotoxic neuronal injury. However, the mechanisms of cPLA2α toxicity...
Shimo, Tsuyoshi, Matsumura, Shinsuke, Ibaragi, Soichiro, Isowa, Sachiko, Kishimoto, Koji, Mese, Hiroshi, ...
Osteosarcoma is the most common primary malignant bone tumor, accounting for approximately 20% of all primary sarcomas in bone. Although treatment modalities have been improved over the past decades,...