Kouichi Takahashi, Present Postdoctoral Researcher
• Multi-scaleness, space, and algorithmic heterogeneity in cell biological simulations. • Intracellular molecular crowding and its impacts on signaling pathways. • Software architecture and...
Distributed Cell Biology Simulations with E-Cell System (2008)
Masahiro Sugimoto, Kouichi Takahashi, Tomoya Kitayama, Daiki Ito, Masaru Tomita
Abstract. Many useful applications of simulation in computational cell biology, e.g. kinetic parameter estimation, Metabolic Control Analysis (MCA), and bifurcation analysis, require a large number...
Development of Integrated Modeling Environment for E-Cell3 System (2008)
Gabor Bereczki, Kouichi Takahashi, Takeshi Sakurada, Ng Yan, Hong Masaru Tomita
E-Cell Project[1,2] at Keio University is aimed at the computer aided reconstruction, simulation and eventually engineering of the complete spectra of cellular phenomena. As an extension to the...
Genome Informatics 14: 294--295 (2003) E - Cell System Version 3: A Software Platform for (2008)
Integrative Computational Biology, Kouichi Takahashi, Takeshi Sakurada, Kazunari Kaizu, Tomoya Kitayama, Satya Arjunan, ...
Introduction E - Cell System is an OpenSource software environment for modeling, simulation and mathematical analysis of the cell (http://www.e-cell.org/software). Unlike its preceding versions, E -...
Kouichi Takahashi, Satya N, A Vel Arjunan, Masaru Tomita
Abstract How cells utilize intracellular spatial features to optimize their signaling characteristics is still not clearly understood. The physical distance between the cell-surface receptor and the...
高橋, 恒一, タカハシ, コウイチ, Takahashi, Kouichi, 冨田, 勝, トミタ, マサル, Tomita, Masaru
Author
A Multi-Algorithm, Multi-Timescale Method for Cell Simulation (2004)
Kouichi Takahashi, Kazunari Kaizu, Bin Hu, Masaru Tomita
Motivation Many important problems in cell biology require the dense nonlinear interactions between functional modules to be considered. The importance of computer simulation in understanding...
A multi-algorithm, multi-timescale method for cell simulation (2004)
Takahashi, Kouichi, Kaizu, Kazunari, Hu, Bin, Tomita, Masaru
Motivation Many important problems in cell biology require the dense nonlinear interactions between functional modules to be considered. The importance of computer simulation in understanding...
A multi-algorithm, multi-timescale method for cell simulation (2004)
Takahashi, Kouichi, Kaizu, Kazunari, Hu, Bin, Tomita, Masaru
Motivation: Many important problems in cell biology require the dense nonlinear interactions between functional modules to be considered. The importance of computer simulation in understanding...
A multi-algorithm, multi-timescale method for cell simulation (2004)
Takahashi, Kouichi, Kaizu, Kazunari, Hu, Bin, Tomita, Masaru
Motivation Many important problems in cell biology require the dense nonlinear interactions between functional modules to be considered. The importance of computer simulation in understanding...
E-CELL project overview: towards integrative simulation of cellular processes (1998)
Masaru Tomita, Kenta Hashimoto, Kouichi Takahashi, Yuri Matsuzaki, Ryo Matsushima, Kanako Saito, ...
12 Hisako Nakano 14
Yusuke Saito, Kouichi Takahashi, Masaru Tomita
We applied multivariate time series analysis to metabolic models constructed using the E-CELL system. The E-CELL system [1] is a generic simulation environment for modeling cellular processes at...
E-CELL project overview: towards integrative simulation of cellular processes (1998)
Masaru Tomita, Kenta Hashimoto, Kouichi Takahashi, Yuri Matsuzaki, Ryo Matsushima, Kanako Saito, ...
12 Hisako Nakano 14
Five-antituberculosis Drug-resistance Genes Detection Using Array System
Shimizu, Yasuo, Dobashi, Kunio, Yoshikawa, Yoko, Yabe, Shigeki, Higuchi, Seiichi, Koike, Yoko, ...
Detection of resistance to drugs for Mycobacterium tuberculosis takes about two months from the sample collection using culture-based methods. To test a rapid method for detection of resistance for...