Breckpot, Karine, Aerts-Toegaert, Cindy, Heirman, Carlo, Peeters, Uschi, Beyaert, Rudi, Aerts, Joeri L, ...
revert established Th2 sensitization (2008)
Harmjan Kuipers, Carlo Heirman, Daniëlle Hijdra, Femke Muskens, Monique Willart, Sonja Van Meirvenne, ...
Dendritic cells retrovirally overexpressing IL-12 induce strong
Henry, E, Desmet, Christophe, Garze, V, Fievez, Laurence, Bedoret, Denis, Heirman, C, ...
Dendritic cells (DCs) are professional APCs that have a unique capacity to initiate primary immune responses, including tolerogenic responses. We have genetically engineered bone marrow-derived DCs...
Cognitive deficits and striato-frontal dopamine release in Parkinson's disease (2008)
Sawamoto, Nobukatsu, Piccini, Paola, Hotton, Gary, Pavese, Nicola, Thielemans, Kris, Brooks, David J.
Idiopathic Parkinson's disease (PD) is often accompanied by a pattern of executive deficits similar to those found in patients with frontal lobe lesions. We investigated whether such cognitive...
Matthew W. Jacobson, Dan Ruan, Somesh Srivastava, Kim Khalsa, Hugo Shi, Eran Bashan Special, ...
In memory of my grandfather, Isadore Shore. May he rest in peace. ii ACKNOWLEDGEMENTS I would like to express sincerest thanks to my advisor, Prof. Jeff Fessler, for his guid-ance and support, as...
Correction of Head Movement on PET Studies: Comparison of Methods (2006)
Andrew J. Montgomery, Kris Thielemans, Mitul A. Mehta, Federico Turkheimer, Sanida Mustafovic, Paul M. Grasby
Head movement presents a continuing problem in PET studies. Head restraint minimizes movement but is unreliable, resulting in the need to develop alternative strategies. These include frame-by-frame...
Van De Casteele, Marc, Caluwé, Natascha, Stangé, Geert, Breckpot, Karine, Thielemans, Kris, ...
AIMS/HYPOTHESIS: In the human pancreas, a close topographic relationship exists between duct cells and beta cells. This explains the high proportion of duct cells in isolated human islet...
Specific killing of lymphoma cells by cytotoxic T-cells mediated by a bispecific diabody (1996)
Holliger, Philipp, Brissinck, Jan, Williams, Roger L., Thielemans, Kris, Winter, Greg
Antibody fragments produced by bacterial fermentation lack natural effector functions. Bispecific antibody fragments, however, can be endowed with effector functions, for example cell-mediated...
A Mathematica Package for Computing N=2 Superfield Operator Product Expansions (1995)
Krivonos, Sergey, Thielemans, Kris
We describe a general purpose Mathematica package for computing Superfield Operator Product Expansions in meromorphic $N=2$ superconformal field theory. Given the SOPEs for a set of ``basic"...
Gauging Conformal Algebras with Relations between the Generators (1995)
Thielemans, Kris, Vandoren, Stefan
We investigate the gauging of conformal algebras with relations between the generators. We treat the $W_{5/2}$--algebra as a specific example. We show that the gauge-algebra is in general reducible...
An Algorithmic Approach to Operator Product Expansions, $W$-Algebras and $W$-Strings (1995)
String theory is currently the most promising theory to explain the spectrum of the elementary particles and their interactions. One of its most important features is its large symmetry group, which...
Muraille, Eric, De Becker, Geneviève, Bakkus, Marleen, Thielemans, Kris, Urbain, Jacques, Moser, Muriel, ...
Staphylococcus enterotoxins bind class II MHC molecules on antigen presenting cells (APC) and stimulate T cells expressing appropriate Vβ gene products. Although the role of non-TCR associated...
The Relation between Linear and Non-Linear $N=3,4$ Supergravity Theories (1993)
Sevrin, Alexander, Thielemans, Kris, Troost, Walter
The effective actions for $d=2$, $N=3,4$ chiral supergravities with a linear and a non-linear gauge algebra are related to each other by a quantum reduction, the latter is obtained from the former by...
Induced and Effective Gravity Theories in D=2 (1993)
Sevrin, Alexander, Thielemans, Kris, Troost, Walter
As a preparation for the study of {\it arbitrary} extensions of $d=2$ gravity we present a detailed investigation of $SO(N)$ supergravity. By gauging a chiral, nilpotent subgroup of the $OSp(N|2)$...
Veide, Hilde Van De, Lorré, Katrien, Bakkus, Marleen, Thielemans, Kris, Ceuppens, Jan L., Boer, Mark De, ...
Co-stimulatory signals are absolutely required for T cell activation after TCR–MHC-peptide interaction. The most important co-stimulatory signal known so far is mediated by the interaction of CD28...
CD40 Ligation Prevents Trypanosoma cruzi Infection through Interleukin-12 Upregulation
Chaussabel, Damien, Jacobs, Frédérique, De Jonge, Jan, De Veerman, Marijke, Carlier, Yves, Thielemans, Kris, ...
Because of the critical role of the CD40-CD40 ligand (CD40L) pathway in the induction and effector phases of immune responses, we investigated the effects of CD40 ligation on the control of...
Fontt, Elizabeth Olivares, De Baetselier, Patrick, Heirman, Carlo, Thielemans, Kris, Lucas, Ralph, Vray, Bernard
We have previously shown that the addition of exogenous granulocyte-macrophage colony-stimulating factor (GM-CSF) to nonactivated mouse peritoneal macrophages (MPM) limits Trypanosoma cruzi...
Lambrecht, Bart N., De Veerman, Marijke, Coyle, Anthony J., Gutierrez-Ramos, Jose-Carlos, Thielemans, Kris, Pauwels, Romain A.
The aim of this study was to investigate whether dendritic cells (DCs) can induce sensitization to aeroallergen in a mouse model of allergic asthma. Ovalbumin-pulsed (OVA-pulsed) or unpulsed myeloid...
Borg, Christophe, Terme, Magali, Taïeb, Julien, Ménard, Cédric, Flament, Caroline, Robert, Caroline, ...
Mutant isoforms of the KIT or PDGF receptors expressed by gastrointestinal stromal tumors (GISTs) are considered the therapeutic targets for STI571 (imatinib mesylate; Gleevec), a specific inhibitor...
Lonchay, Christophe, Van Der Bruggen, Pierre, Connerotte, Thierry, Hanagiri, Takeshi, Coulie, Pierre, Colau, Didier, ...
The cancer-germline gene MAGE-3 codes for tumor-specific antigens recognized on many tumors by T lymphocytes. A MAGE-3 antigen presented by HLA-A1 has been used in several vaccination trials on...
CD40 Ligation Prevents Trypanosoma cruzi Infection through Interleukin-12 Upregulation
Chaussabel, Damien, Jacobs, Frédérique, De Jonge, Jan, De Veerman, Marijke, Carlier, Yves, Thielemans, Kris, ...
Because of the critical role of the CD40-CD40 ligand (CD40L) pathway in the induction and effector phases of immune responses, we investigated the effects of CD40 ligation on the control of...
Fontt, Elizabeth Olivares, De Baetselier, Patrick, Heirman, Carlo, Thielemans, Kris, Lucas, Ralph, Vray, Bernard
We have previously shown that the addition of exogenous granulocyte-macrophage colony-stimulating factor (GM-CSF) to nonactivated mouse peritoneal macrophages (MPM) limits Trypanosoma cruzi...
Lambrecht, Bart N., De Veerman, Marijke, Coyle, Anthony J., Gutierrez-Ramos, Jose-Carlos, Thielemans, Kris, Pauwels, Romain A.
The aim of this study was to investigate whether dendritic cells (DCs) can induce sensitization to aeroallergen in a mouse model of allergic asthma. Ovalbumin-pulsed (OVA-pulsed) or unpulsed myeloid...
Borg, Christophe, Terme, Magali, Taïeb, Julien, Ménard, Cédric, Flament, Caroline, Robert, Caroline, ...
Mutant isoforms of the KIT or PDGF receptors expressed by gastrointestinal stromal tumors (GISTs) are considered the therapeutic targets for STI571 (imatinib mesylate; Gleevec), a specific inhibitor...
Lonchay, Christophe, Van Der Bruggen, Pierre, Connerotte, Thierry, Hanagiri, Takeshi, Coulie, Pierre, Colau, Didier, ...
The cancer-germline gene MAGE-3 codes for tumor-specific antigens recognized on many tumors by T lymphocytes. A MAGE-3 antigen presented by HLA-A1 has been used in several vaccination trials on...
Maldonado-López, Roberto, De Smedt, Thibaut, Michel, Patrick, Godfroid, Jacques, Pajak, Bernard, Heirman, Carlo, ...
Cells of the dendritic family display some unique properties that confer to them the capacity to sensitize naive T cells in vitro and in vivo. In the mouse, two subclasses of dendritic cells (DCs)...
Identification of MAGE-3 Epitopes Presented by HLA-DR Molecules to CD4+ T Lymphocytes
Chaux, Pascal, Vantomme, Valérie, Stroobant, Vincent, Thielemans, Kris, Corthals, Jurgen, Luiten, Rosalie, ...
MAGE-type genes are expressed by many tumors of different histological types and not by normal cells, except for male germline cells, which do not express major histocompatibility complex (MHC)...
Moulin, Véronique, Andris, Fabienne, Thielemans, Kris, Maliszewski, Charlie, Urbain, Jacques, Moser, Muriel
Increasing evidence indicates that dendritic cells (DCs) are the antigen-presenting cells of the primary immune response. However, several reports suggest that B lymphocytes could be required for...
GeurtsvanKessel, Corine H., Willart, Monique A.M., Van Rijt, Leonie S., Muskens, Femke, Kool, Mirjam, Baas, Chantal, ...
Although dendritic cells (DCs) play an important role in mediating protection against influenza virus, the precise role of lung DC subsets, such as CD11b− and CD11b+ conventional DCs or...