Krishna Murthy

Immunization with Hepatitis C Virus-Like Particles Induces Humoral and Cellular Immune Responses in Nonhuman Primates

Jeong, Sook-Hyang, Qiao, Ming, Nascimbeni, Michelina, Hu, Zongyi, Rehermann, Barbara, Murthy, Krishna, ...

We have previously reported the production of hepatitis C virus-like particles (HCV-LP) using a recombinant baculovirus containing the cDNA of the HCV structural proteins (core, E1, and E2). These...

Immunization with Hepatitis C Virus-Like Particles Induces Humoral and Cellular Immune Responses in Nonhuman Primates

Jeong, Sook-Hyang, Qiao, Ming, Nascimbeni, Michelina, Hu, Zongyi, Rehermann, Barbara, Murthy, Krishna, ...

We have previously reported the production of hepatitis C virus-like particles (HCV-LP) using a recombinant baculovirus containing the cDNA of the HCV structural proteins (core, E1, and E2). These...

Production of Infectious Hepatitis C Virus of Various Genotypes in Cell Culturesâ–ż

Kato, Takanobu, Matsumura, Takuya, Heller, Theo, Saito, Satoru, Sapp, Ronda K., Murthy, Krishna, ...

A unique hepatitis C virus (HCV) strain JFH-1 has been shown to replicate efficiently in cell culture with production of infectious HCV. We previously developed a DNA expression system containing HCV...

Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees

Elmowalid, Gamal A., Qiao, Ming, Jeong, Sook-Hyang, Borg, Brian B., Baumert, Thomas F., Sapp, Ronda K., ...

Recombinant hepatitis C virus (HCV)-like particles (HCV-LPs) containing HCV structural proteins (core, E1, and E2) produced in insect cells resemble the putative HCV virions and are capable of...