Dynamics of Lysozyme Structure Network: Probing the Process of Unfolding (2007)
Ghosh, Amit, Brinda, KV, Vishveshwara, Saraswathi
Recently we showed that the three-dimensional structure of proteins can be investigated from a network perspective, where the amino acid residues represent the nodes in the network and the...
Dynamics of Lysozyme Structure Network: Probing the Process of Unfolding (2007)
Ghosh, Amit, Brinda, KV, Vishveshwara, Saraswathi
Recently we showed that the three-dimensional structure of proteins can be investigated from a network perspective, where the amino acid residues represent the nodes in the network and the...
Characterization of the backbone geometry of protein native state structures (2006)
Brinda, KV, Vishveshwara, Saraswathi
We present a simple method for analyzing the geometry of noncovalent residue–residue interactions stabilizing the protein structure, which takes into account the constraints on the local backbone...
Sathyapriya, R, Brinda, KV, Vishveshwara, Saraswathi
The structure networks of DNA-binding proteins have been constructed and analyzed. The detailed analysis of the networks indicates a strong relation between the positions of the residues interacting...
Characterization of the backbone geometry of protein native state structures (2006)
Brinda, KV, Vishveshwara, Saraswathi
We present a simple method for analyzing the geometry of noncovalent residue–residue interactions stabilizing the protein structure, which takes into account the constraints on the local backbone...
Sathyapriya, R, Brinda, KV, Vishveshwara, Saraswathi
The structure networks of DNA-binding proteins have been constructed and analyzed. The detailed analysis of the networks indicates a strong relation between the positions of the residues interacting...
Oligomeric protein structure networks: insights into protein-protein interactions (2005)
Brinda, KV, Vishveshwara, Saraswathi
Abstract Background Protein-protein association is essential for a variety of cellular processes and hence a large number of investigations are being carried out to understand the principles of...
Oligomeric protein structure networks: insights into protein-protein interactions (2005)
Brinda, KV, Vishveshwara, Saraswathi
Background Protein-protein association is essential for a variety of cellular processes and hence a large number of investigations are being carried out to understand the principles of...
Brinda, KV, Surolia, Avadhesha, Vishveshwara, Sarawathi
The unique three-dimensional structure of both monomeric and oligomeric proteins is encoded in their sequence. The biological functions of proteins are dependent on their tertiary and quaternary...
Sistla, Ramesh K, Brinda, KV, Vishveshwara, Saraswathi
We present a novel method for the identification of structural domains and domain interface residues in proteins by graph spectral method.This method converts the three-dimensional structure of the...
Sistla, Ramesh K, Brinda, KV, Vishveshwara, Saraswathi
We present a novel method for the identification of structural domains and domain interface residues in proteins by graph spectral method.This method converts the three-dimensional structure of the...
A Graph Spectral Analysis of the Structural Similarity Network of Protein Chains (2005)
Krishnadev, O, Brinda, KV, Vishveshwara, Saraswathi
We present a simple method for the analysis of large networks based on their graph spectral properties. One of the advantages of this method is that it uses a single numerical computation to identify...
Brinda, KV, Surolia, Avadhesha, Vishveshwara, Sarawathi
The unique three-dimensional structure of both monomeric and oligomeric proteins is encoded in their sequence. The biological functions of proteins are dependent on their tertiary and quaternary...
Oligomeric protein structure networks: insights into protein-protein interactions (2005)
Brinda, KV, Vishveshwara, Saraswathi
Background Protein-protein association is essential for a variety of cellular processes and hence a large number of investigations are being carried out to understand the principles of...
A Graph Spectral Analysis of the Structural Similarity Network of Protein Chains (2005)
Krishnadev, O, Brinda, KV, Vishveshwara, Saraswathi
We present a simple method for the analysis of large networks based on their graph spectral properties. One of the advantages of this method is that it uses a single numerical computation to identify...
Determinants of quaternary association in legume lectins (2004)
Brinda, KV, Mitra, Nivedita, Surolia, Avadhesha, Vishveshwara, Saraswathi
It is well known that the sequence of amino acids in proteins code for its tertiary structure. It is also known that there exists a relationship between sequence and the quaternary structure of...
Determinants of quaternary association in legume lectins (2004)
Brinda, KV, Mitra, Nivedita, Surolia, Avadhesha, Vishveshwara, Saraswathi
It is well known that the sequence of amino acids in proteins code for its tertiary structure. It is also known that there exists a relationship between sequence and the quaternary structure of...
Analysis of homodimeric protein interfaces by graph-spectral methods (2002)
Brinda, KV, Kannan, N, Vishveshwara, S
The quaternary structures impart structural and functional credibility to proteins. In a multi-subunit protein, it is important to understand the factors that drive the association or dissociation of...
Analysis of homodimeric protein interfaces by graph-spectral methods (2002)
Brinda, KV, Kannan, N, Vishveshwara, S
The quaternary structures impart structural and functional credibility to proteins. In a multi-subunit protein, it is important to understand the factors that drive the association or dissociation of...