Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors
Dace, Alexandra, Zhao, Li, Park, Kyung Soo, Furuno, T., Takamura, N., Nakanishi, M., ...
The thyroid hormone 3,3′,5-triiodo-l-thyronine (T3) is essential for growth, differentiation, and development. Its biological activities are mediated by T3 nuclear receptors (TRs). At present, how...
Zhu, Xu-guang, Park, Kyung Soo, Kaneshige, Masahiro, Bhat, Manoj K., Zhu, Qihong, Mariash, Cary N., ...
Thyroid hormone (T3) nuclear receptors (TR) are ligand-dependent transcription factors which regulate growth, differentiation, and development. One emerging hypothesis suggests that TR mediate these...
Miller, Lance D., Park, Kyung Soo, Guo, Qingbin M., Alkharouf, Nawal W., Malek, Renae L., Lee, Norman H., ...
To investigate the transcriptional program underlying thyroid hormone (T3)-induced cell proliferation, cDNA microarrays were used to survey the temporal expression profiles of 4,400 genes. Of 358...
Hormone binding induces rapid proteasome-mediated degradation of thyroid hormone receptors
Dace, Alexandra, Zhao, Li, Park, Kyung Soo, Furuno, T., Takamura, N., Nakanishi, M., ...
The thyroid hormone 3,3′,5-triiodo-l-thyronine (T3) is essential for growth, differentiation, and development. Its biological activities are mediated by T3 nuclear receptors (TRs). At present, how...
Zhu, Xu-guang, Park, Kyung Soo, Kaneshige, Masahiro, Bhat, Manoj K., Zhu, Qihong, Mariash, Cary N., ...
Thyroid hormone (T3) nuclear receptors (TR) are ligand-dependent transcription factors which regulate growth, differentiation, and development. One emerging hypothesis suggests that TR mediate these...
Miller, Lance D., Park, Kyung Soo, Guo, Qingbin M., Alkharouf, Nawal W., Malek, Renae L., Lee, Norman H., ...
To investigate the transcriptional program underlying thyroid hormone (T3)-induced cell proliferation, cDNA microarrays were used to survey the temporal expression profiles of 4,400 genes. Of 358...