L. A. Campbell

Publication List Details

Period

1959 - 2008

Number

51

Co-Authors

A 6 week course of azithromycin treatment has no beneficial effect on atherosclerotic lesion development in apolipoprotein E-deficient mice chronically infected with Chlamydia pneumoniae (2005)

Blessing, E., Campbell, L. A., Rosenfeld, M. E., Chesebro, B.

Objectives: To evaluate whether antimicrobial chemotherapy prevents acceleration of atherosclerotic lesion development induced by infection with Chlamydia pneumoniae. Methods: ApoE-deficient mice...

A 6 week course of azithromycin treatment has no beneficial effect on atherosclerotic lesion development in apolipoprotein E-deficient mice chronically infected with Chlamydia pneumoniae (2005)

Blessing, E., Campbell, L. A., Rosenfeld, M. E., Chesebro, B.

Objectives: To evaluate whether antimicrobial chemotherapy prevents acceleration of atherosclerotic lesion development induced by infection with Chlamydia pneumoniae. Methods: ApoE-deficient mice...

TRACE Trajectory Analysis and Orbit Determination Program. Volume 13. Square Root Information Filtering and Smoothing. (1998)

Campbell, L. A.

The TRACE Trajectory Analysis and Orbit Determination Program is a general purpose orbital analysis program. It was developed specifically to assist technical personnel in the analysis and design of...

Isolating and Transforming an Ada Heapsort for SDVS Analysis. (1998)

Campbell, L. A.

This report examines some of the issues that arise when the State Delta Verification System (SDVS) is used for the analysis of code fragments extracted from larger bodies of 'production' code. The...

Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old).

Kuo, C C, Grayston, J T, Campbell, L A, Goo, Y A, Wissler, R W, Benditt, E P

An association of Chlamydia pneumoniae with atherosclerosis of coronary and carotid arteries and aorta has been found by seroepidemiology and by demonstration of the organism in atheromata....

Effects of two antibiotic regimens on course and persistence of experimental Chlamydia pneumoniae TWAR pneumonitis.

Malinverni, R, Kuo, C C, Campbell, L A, Lee, A, Grayston, J T

We studied the effects of two antibiotic regimens on the course of Chlamydia pneumoniae infection in the lungs of Swiss Webster mice. After intranasal challenge with isolates AR-388 (1.3 x 10(7)...

Chlamydia pneumoniae (TWAR).

Kuo, C C, Jackson, L A, Campbell, L A, Grayston, J T

Chlamydia pneumoniae (TWAR) is a recently recognized third species of the genus Chlamydia that causes acute respiratory disease. It is distinct from the other two chlamydial species that infect...

Isolation and characterization of a gene encoding a Chlamydia pneumoniae 76-kilodalton protein containing a species-specific epitope.

Perez Melgosa, M, Kuo, C C, Campbell, L A

Chlamydia pneumoniae is a human respiratory pathogen. Unlike the other two Chlamydia species, no species-specific antigen has been defined for C. pneumoniae. An immunoreactive clone containing a...

Effects of quinolone analog CI-960 in a monkey model of Chlamydia trachomatis salpingitis.

Patton, D L, Cosgrove, Y T, Kuo, C C, Campbell, L A

Several quinolones have been shown to have antichlamydial activity in vitro and in vivo. We evaluated the effects of the quinolone CI-960 (Parke-Davis) on primary or repeated chlamydial infection in...

Autoplaquing in Neisseria gonorrhoeae.

Campbell, L A, Short, H B, Young, F E, Clark, V L

Irregularly shaped autoplaques were observed on a lawn of two different strains of Neisseria gonorrhoeae. Autoplaquing occurred on gonococcal genetic medium lacking arginine and was noninducible on...

Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair.

Campbell, L A, Yasbin, R E

The lethal and mutagenic effects of various mutagens on Neisseria gonorrhoeae were investigated. Lethality studies demonstrated that N. gonorrhoeae was relatively sensitive to ethyl methanesulfonate,...

Deoxyribonucleic acid repair capacities of Neisseria gonorrhoeae: absence of photoreactivation.

Campbell, L A, Yasbin, R E

No difference in survival was observed when ultraviolet-irradiated gonococcal cells were subsequently incubated in the dark or exposed to photoreactivating light. This observation indicates that...

Sequence analysis of the gene encoding the Chlamydia pneumoniae DnaK protein homolog.

Kornak, J M, Kuo, C C, Campbell, L A

The antigen-coding region of a 4.2-kb PstI fragment of Chlamydia pneumoniae (pLC3), which encodes a 75-kDa immunoreactive protein recognized during human C. pneumoniae infection, was localized to a...

Sequence analysis of the major outer membrane protein gene of Chlamydia pneumoniae.

Perez Melgosa, M, Kuo, C C, Campbell, L A

Compared with the major outer membrane proteins (MOMPs) of the other chlamydial species, the Chlamydia pneumoniae MOMP appears to be less antigenically complex, and as determined by immunoblot...

Structural and antigenic analysis of Chlamydia pneumoniae.

Campbell, L A, Kuo, C C, Grayston, J T

Several isolates of Chlamydia pneumoniae were compared with each other and to Chlamydia trachomatis and Chlamydia psittaci by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and...

Isolation and sequence analysis of the Chlamydia pneumoniae GroE operon.

Kikuta, L C, Puolakkainen, M, Kuo, C C, Campbell, L A

Chlamydia pneumoniae has emerged as an important human respiratory pathogen. From a lambda gt11 gene bank constructed from C. pneumoniae isolate AR-39 DNA, an immunoreactive plaque containing a...

Induction and repression of outer membrane proteins by anaerobic growth of Neisseria gonorrhoeae.

Clark, V L, Campbell, L A, Palermo, D A, Evans, T M, Klimpel, K W

Neisseria gonorrhoeae is generally considered to be an obligate aerobe; it can, however, grow in the absence of oxygen by anaerobic respiration by using nitrite as a terminal electron acceptor. The...

Detection of Chlamydia pneumoniae by polymerase chain reaction.

Campbell, L A, Perez Melgosa, M, Hamilton, D J, Kuo, C C, Grayston, J T

While criteria for serodiagnosis of Chlamydia pneumoniae infection are well established, isolation of the organism is often difficult. To increase detection of this organism, C. pneumoniae-specific...

Serological response to Chlamydia pneumoniae in adults with coronary arterial fatty streaks and fibrolipid plaques.

Puolakkainen, M, Kuo, C C, Shor, A, Wang, S P, Grayston, J T, Campbell, L A

The antigen-specific serological response to Chlamydia pneumoniae was studied in 45 adults with coronary artery atherosclerosis and compared with that in 40 adults with acute respiratory infection....

Serological response to Chlamydia pneumoniae infection.

Campbell, L A, Kuo, C C, Wang, S P, Grayston, J T

The human serological response was analyzed by using sera from patients who were serologically positive but isolation negative for Chlamydia pneumoniae and from patients with proven C. pneumoniae...

Characterization of the new Chlamydia agent, TWAR, as a unique organism by restriction endonuclease analysis and DNA-DNA hybridization.

Campbell, L A, Kuo, C C, Grayston, J T

Several molecular techniques were used for comparison of the novel Chlamydia agent, TWAR, with Chlamydia trachomatis and Chlamydia psittaci. Unlike all serotypes of C. trachomatis and most strains of...

Isolation of a gene encoding a Chlamydia sp. strain TWAR protein that is recognized during infection of humans.

Campbell, L A, Kuo, C C, Thissen, R W, Grayston, J T

Chlamydia sp. strain TWAR is a unique Chlamydia sp. that causes acute respiratory disease. A gene bank consisting of TWAR isolate AR-39 DNA in pUC19 was screened with anti-AR-39 rabbit immune sera....

Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old).

Kuo, C C, Grayston, J T, Campbell, L A, Goo, Y A, Wissler, R W, Benditt, E P

An association of Chlamydia pneumoniae with atherosclerosis of coronary and carotid arteries and aorta has been found by seroepidemiology and by demonstration of the organism in atheromata....

Effects of two antibiotic regimens on course and persistence of experimental Chlamydia pneumoniae TWAR pneumonitis.

Malinverni, R, Kuo, C C, Campbell, L A, Lee, A, Grayston, J T

We studied the effects of two antibiotic regimens on the course of Chlamydia pneumoniae infection in the lungs of Swiss Webster mice. After intranasal challenge with isolates AR-388 (1.3 x 10(7)...

Chlamydia pneumoniae (TWAR).

Kuo, C C, Jackson, L A, Campbell, L A, Grayston, J T

Chlamydia pneumoniae (TWAR) is a recently recognized third species of the genus Chlamydia that causes acute respiratory disease. It is distinct from the other two chlamydial species that infect...

Isolation and characterization of a gene encoding a Chlamydia pneumoniae 76-kilodalton protein containing a species-specific epitope.

Perez Melgosa, M, Kuo, C C, Campbell, L A

Chlamydia pneumoniae is a human respiratory pathogen. Unlike the other two Chlamydia species, no species-specific antigen has been defined for C. pneumoniae. An immunoreactive clone containing a...

Effects of quinolone analog CI-960 in a monkey model of Chlamydia trachomatis salpingitis.

Patton, D L, Cosgrove, Y T, Kuo, C C, Campbell, L A

Several quinolones have been shown to have antichlamydial activity in vitro and in vivo. We evaluated the effects of the quinolone CI-960 (Parke-Davis) on primary or repeated chlamydial infection in...

Autoplaquing in Neisseria gonorrhoeae.

Campbell, L A, Short, H B, Young, F E, Clark, V L

Irregularly shaped autoplaques were observed on a lawn of two different strains of Neisseria gonorrhoeae. Autoplaquing occurred on gonococcal genetic medium lacking arginine and was noninducible on...

Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair.

Campbell, L A, Yasbin, R E

The lethal and mutagenic effects of various mutagens on Neisseria gonorrhoeae were investigated. Lethality studies demonstrated that N. gonorrhoeae was relatively sensitive to ethyl methanesulfonate,...

Deoxyribonucleic acid repair capacities of Neisseria gonorrhoeae: absence of photoreactivation.

Campbell, L A, Yasbin, R E

No difference in survival was observed when ultraviolet-irradiated gonococcal cells were subsequently incubated in the dark or exposed to photoreactivating light. This observation indicates that...

Sequence analysis of the gene encoding the Chlamydia pneumoniae DnaK protein homolog.

Kornak, J M, Kuo, C C, Campbell, L A

The antigen-coding region of a 4.2-kb PstI fragment of Chlamydia pneumoniae (pLC3), which encodes a 75-kDa immunoreactive protein recognized during human C. pneumoniae infection, was localized to a...

Sequence analysis of the major outer membrane protein gene of Chlamydia pneumoniae.

Perez Melgosa, M, Kuo, C C, Campbell, L A

Compared with the major outer membrane proteins (MOMPs) of the other chlamydial species, the Chlamydia pneumoniae MOMP appears to be less antigenically complex, and as determined by immunoblot...

Structural and antigenic analysis of Chlamydia pneumoniae.

Campbell, L A, Kuo, C C, Grayston, J T

Several isolates of Chlamydia pneumoniae were compared with each other and to Chlamydia trachomatis and Chlamydia psittaci by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and...

Isolation and sequence analysis of the Chlamydia pneumoniae GroE operon.

Kikuta, L C, Puolakkainen, M, Kuo, C C, Campbell, L A

Chlamydia pneumoniae has emerged as an important human respiratory pathogen. From a lambda gt11 gene bank constructed from C. pneumoniae isolate AR-39 DNA, an immunoreactive plaque containing a...

Induction and repression of outer membrane proteins by anaerobic growth of Neisseria gonorrhoeae.

Clark, V L, Campbell, L A, Palermo, D A, Evans, T M, Klimpel, K W

Neisseria gonorrhoeae is generally considered to be an obligate aerobe; it can, however, grow in the absence of oxygen by anaerobic respiration by using nitrite as a terminal electron acceptor. The...

Detection of Chlamydia pneumoniae by polymerase chain reaction.

Campbell, L A, Perez Melgosa, M, Hamilton, D J, Kuo, C C, Grayston, J T

While criteria for serodiagnosis of Chlamydia pneumoniae infection are well established, isolation of the organism is often difficult. To increase detection of this organism, C. pneumoniae-specific...

Serological response to Chlamydia pneumoniae in adults with coronary arterial fatty streaks and fibrolipid plaques.

Puolakkainen, M, Kuo, C C, Shor, A, Wang, S P, Grayston, J T, Campbell, L A

The antigen-specific serological response to Chlamydia pneumoniae was studied in 45 adults with coronary artery atherosclerosis and compared with that in 40 adults with acute respiratory infection....

Serological response to Chlamydia pneumoniae infection.

Campbell, L A, Kuo, C C, Wang, S P, Grayston, J T

The human serological response was analyzed by using sera from patients who were serologically positive but isolation negative for Chlamydia pneumoniae and from patients with proven C. pneumoniae...

Characterization of the new Chlamydia agent, TWAR, as a unique organism by restriction endonuclease analysis and DNA-DNA hybridization.

Campbell, L A, Kuo, C C, Grayston, J T

Several molecular techniques were used for comparison of the novel Chlamydia agent, TWAR, with Chlamydia trachomatis and Chlamydia psittaci. Unlike all serotypes of C. trachomatis and most strains of...

Isolation of a gene encoding a Chlamydia sp. strain TWAR protein that is recognized during infection of humans.

Campbell, L A, Kuo, C C, Thissen, R W, Grayston, J T

Chlamydia sp. strain TWAR is a unique Chlamydia sp. that causes acute respiratory disease. A gene bank consisting of TWAR isolate AR-39 DNA in pUC19 was screened with anti-AR-39 rabbit immune sera....

Specificity of detection of Chlamydia pneumoniae in cardiovascular atheroma: evaluation of the innocent bystander hypothesis.

Jackson, L. A., Campbell, L. A., Schmidt, R. A., Kuo, C. C., Cappuccio, A. L., Lee, M. J., ...

Chlamydia pneumoniae has been detected in atherosclerotic plaque, raising the question of whether this detection is specific to atheromatous tissue. To evaluate this question, we tested...

Experimental rabbit models of Chlamydia pneumoniae infection.

Moazed, T. C., Kuo, C., Patton, D. L., Grayston, J. T., Campbell, L. A.

Chlamydia pneumoniae (TWAR), a common cause of acute respiratory disease in humans, has recently been associated with coronary and aortic atherosclerosis. In this study, we evaluated rabbit models of...

Potential infectious etiologies of atherosclerosis: a multifactorial perspective.

O'Connor, S., Taylor, C., Campbell, L. A., Epstein, S., Libby, P.

Coronary heart disease (CHD) contributes substantially to illness and death worldwide. Experimental studies demonstrate that infection can stimulate atherogenic processes. This review presents a...

Chlamydia pneumoniae and cardiovascular disease.

Campbell, L. A., Kuo, C. C., Grayston, J. T.

Chlamydia pneumoniae is a ubiquitous pathogen that causes acute respiratory disease. The spectrum of C. pneumoniae infection has been extended to atherosclerosis and its clinical manifestations....