L. Andrew Staehelin

Cytokinesis in Tobacco BY-2 and Root Tip Cells: A New Model of Cell Plate Formation in Higher Plants (2009)

A. Lacey Samuels, Thomas H. Giddings, L. Andrew Staehelin

Abstract. Cell plate formation in tobacco root tips and synchronized dividing suspension cultured tobacco BY-2 cells was examined using cryofixation and immu-nocytochemical methods. Due to the much...

Electron Tomographic Analysis of Somatic Cell Plate Formation in Meristematic Cells of Arabidopsis Preserved by High-Pressure Freezing W (2009)

Erin A. White, L. Andrew Staehelin

We have investigated the process of somatic-type cytokinesis in Arabidopsis (Arabidopsis thaliana) meristem cells with a three-dimensional resolution of ~7 nm by electron tomography of high-pressure...

The cyclic nucleotide gated cation channel AtCNGC10 traffics from the ER via Golgi vesicles to the plasma membrane of Arabidopsis root and leaf cells (2007)

Christopher, David A, Borsics, Tamas, Yuen, Christen YL, Ullmer, Wendy, Andème-Ondzighi, Christine, Andres, Marilou A, ...

Abstract Background The cyclic nucleotide-gated ion channels (CNGCs) maintain cation homeostasis essential for a wide range of physiological processes in plant cells. However, the precise subcellular...

Improved method for visualizing coated pits, microfilaments, and microtubules in cryofixed and freeze-substituted plant cells (2002)

Murata, Takashi, Karahara, Ichirou, Kozuka, Toshiaki, Giddings, Thomas H., Staehelin, L. Andrew, Mineyuki, Yoshinobu

We have optimized the conditions for visualizing microfilaments, microtubules, and coated pits in the cortical cytoplasm of high‐pressure frozen and freeze‐substituted plant cells. In...

Golgi structure in three dimensions: functional insights from the normal rat kidney cell (1999)

Mark S. Ladinsky, David N. Mastronarde, J. Richard Mcintosh, Kathryn E. Howell, L. Andrew Staehelin

Abstract. Three-dimensional reconstructions of portions of the Golgi complex from cryofixed, freeze-substituted normal rat kidney cells have been made by dual-axis, high-voltage EM tomography at...

Redistribution of Golgi Stacks and Other Organelles during Mitosis and Cytokinesis in Plant Cells1[w]

Nebenführ, Andreas, Frohlick, Jennifer A., Staehelin, L. Andrew

We have followed the redistribution of Golgi stacks during mitosis and cytokinesis in living tobacco BY-2 suspension culture cells by means of a green fluorescent protein-tagged soybean α-1,2...

Stop-and-Go Movements of Plant Golgi Stacks Are Mediated by the Acto-Myosin System1

Nebenführ, Andreas, Gallagher, Larry A., Dunahay, Terri G., Frohlick, Jennifer A., Mazurkiewicz, Anna M., Meehl, Janet B., ...

The Golgi apparatus in plant cells consists of a large number of independent Golgi stack/trans-Golgi network/Golgi matrix units that appear to be randomly distributed throughout the cytoplasm. To...

Nodal Endoplasmic Reticulum, a Specialized Form of Endoplasmic Reticulum Found in Gravity-Sensing Root Tip Columella Cells1

Zheng, Hui Qiong, Staehelin, L. Andrew

The endoplasmic reticulum (ER) of columella root cap cells has been postulated to play a role in gravity sensing. We have re-examined the ultrastructure of columella cells in tobacco (Nicotiana...

Amyloplast Sedimentation Dynamics in Maize Columella Cells Support a New Model for the Gravity-Sensing Apparatus of Roots1

Yoder, Thomas L., Zheng, Hui-qiong, Todd, Paul, Staehelin, L. Andrew

Quantitative analysis of statolith sedimentation behavior was accomplished using videomicroscopy of living columella cells of corn (Zea mays) roots, which displayed no systematic cytoplasmic...

Three-Dimensional Analysis of Syncytial-Type Cell Plates during Endosperm Cellularization Visualized by High Resolution Electron Tomography W⃞

Otegui, Marisa S., Mastronarde, David N., Kang, Byung-Ho, Bednarek, Sebastian Y., Staehelin, L. Andrew

The three-dimensional architecture of syncytial-type cell plates in the endosperm of Arabidopsis has been analyzed at ∼6-nm resolution by means of dual-axis high-voltage electron tomography of...

Syncytial-Type Cell Plates: A Novel Kind of Cell Plate Involved in Endosperm Cellularization of Arabidopsis

Otegui, Marisa, Staehelin, L. Andrew

Cell wall formation in the syncytial endosperm of Arabidopsis was studied by using high-pressure-frozen/freeze-substituted developing seeds and immunocytochemical techniques. The endosperm...

Reevaluation of the Effects of Brefeldin A on Plant Cells Using Tobacco Bright Yellow 2 Cells Expressing Golgi-Targeted Green Fluorescent Protein and COPI AntiseraW⃞

Ritzenthaler, Christophe, Nebenführ, Andreas, Movafeghi, Ali, Stussi-Garaud, Christiane, Behnia, Leila, Pimpl, Peter, ...

Brefeldin A (BFA) causes a block in the secretory system of eukaryotic cells by inhibiting vesicle formation at the Golgi apparatus. Although this toxin has been used in many studies, its effects on...

Developing Seeds of Arabidopsis Store Different Minerals in Two Types of Vacuoles and in the Endoplasmic Reticulum

Otegui, Marisa S., Capp, Roberta, Staehelin, L. Andrew

Mineral-accumulating compartments in developing seeds of Arabidopsis were studied using high-pressure-frozen/freeze-substituted samples. Developing seeds store minerals in three locations: in the...

Tomographic Evidence for Continuous Turnover of Golgi Cisternae in Pichia pastorisV⃞

Mogelsvang, Soren, Gomez-Ospina, Natalia, Soderholm, Jon, Glick, Benjamin S., Staehelin, L. Andrew

The budding yeast Pichia pastoris contains ordered Golgi stacks next to discrete transitional endoplasmic reticulum (tER) sites, making this organism ideal for structure–function studies of the...

Supramolecular structure of stacked and unstacked regions of the photosynthetic membranes of Prochloron sp., a prokaryote

Giddings, Thomas H., Withers, Nancy W., Staehelin, L. Andrew

Freeze-fracture replicas of the photosynthetic prokaryote Prochloron sp., collected at Coconut Island, Hawaii, show that the thylakoids are differentiated into stacked and unstacked regions much like...

Electron Tomographic Analysis of Somatic Cell Plate Formation in Meristematic Cells of Arabidopsis Preserved by High-Pressure FreezingW⃞

Seguí-Simarro, José M., Austin, Jotham R., White, Erin A., Staehelin, L. Andrew

We have investigated the process of somatic-type cytokinesis in Arabidopsis (Arabidopsis thaliana) meristem cells with a three-dimensional resolution of ∼7 nm by electron tomography of...

Three Types of Gap Junctions Interconnecting Intestinal Epithelial Cells Visualized by Freeze-Etching

Staehelin, L. Andrew

Gap junctions are specialized membrane regions that seem to mediate intercellular communication. They appear to contain closely packed arrays of equally sized particles all of which, upon...

Does Gibberellic Acid Induce the Transfer of Lipase from Protein Bodies to Lipid Bodies in Barley Aleurone Cells? 1

Fernandez, Donna E., Staehelin, L. Andrew

We have examined the effect of gibberellic acid (GA3) on the distribution of the enzyme responsible for mobilizing storage triacylglycerol in aleurone cells of Hordeum vulgare L. cv Himalaya. Using...

Immunogold Localization of the L3 Protein of Maize Lipid Bodies during Germination and Seedling Growth 1

Fernandez, Donna E., Qu, Rongda, Huang, Anthony H. C., Staehelin, L. Andrew

We have used antibodies directed against the 16.5 kilodalton protein L3, the most abundant integral protein of maize (Zea mays L. cv Mo 17) lipid bodies, to follow the fate of this protein in...

Compensatory Alterations in the Photochemical Apparatus of a Photoregulatory, Chlorophyll b-Deficient Mutant of Maize 1

Greene, Ben A., Staehelin, L. Andrew, Melis, Anastasios

Characterization of the functional organization of the photochemical apparatus in the light sensitive chlorophyll b-deficient oil yellow-yellow green (OY-YG) mutant of maize (Zea mays) is presented....

Immunogold Localization of Xyloglucan and Rhamnogalacturonan I in the Cell Walls of Suspension-Cultured Sycamore Cells 1

Moore, Patricia J., Darvill, Alan G., Albersheim, Peter, Staehelin, L. Andrew

Plant cell walls serve several functions: they impart rigidity to the plant, provide a physical and chemical barrier between the cell and its environment, and regulate the size and shape of each...

A Second Extensin-Like Hydroxyproline-Rich Glycoprotein from Carrot Cell Walls 1

Stafstrom, Joel P., Staehelin, L. Andrew

The insoluble extensin matrix of dicot cell walls has been studied most fruitfully by examining the salt-extractable precursors to this matrix. Multiple extensin-like hydroxyproline-rich...

Lateral Distribution of the Cytochrome b6/f and Coupling Factor ATP Synthetase Complexes of Chloroplast Thylakoid Membranes 1

Allred, David R., Staehelin, L. Andrew

We have visualized directly the distribution of the cytochrome b6/f and coupling factor ATP synthetase complexes in thylakoid membranes of embedded, thin-sectioned, intact chloroplasts by using...

Isolation of Photosystem I Complexes from Octyl Glucoside/Sodium Dodecyl Sulfate Solubilized Spinach Thylakoids 1: Characterization and Reconstitution into Liposomes

Dunahay, Terri G., Staehelin, L. Andrew

We have used the nonionic detergent octyl-β-d-glucopyranoside in combination with sodium dodecyl sulfate to isolate two novel Photosystem I (PSI) complexes from spinach (Spinacea oleracea L.)...

Structure of the Thylakoids and Envelope Membranes of the Cyanelles of Cyanophora paradoxa1

Giddings, Thomas H., Wasmann, Cathy, Staehelin, L. Andrew

The cyanelles of Cyanophora paradoxa Korsch. are photosynthetically active obligate endosymbionts in which phycobiliproteins serve as the major accessory pigments. Freeze-fracture electron...

A Rapid Reverse Phase Evaporation Method for the Reconstitution of Uncharged Thylakoid Membrane Lipids That Resist Hydration 1

Sprague, Sallie G., Staehelin, L. Andrew

Comparison of several lipid reconstitution methods showed that they were not equally efficient at transferring the predominant thylakoid lipid, monogalactosyldiglyceride (MG), to the aqueous phase....

Isolation and Characterization of a New Minor Chlorophyll a/b-Protein Complex (CP24) from Spinach 1

Dunahay, Terri G., Staehelin, L. Andrew

We have identified a new minor chlorophyll a/b-protein complex in the thylakoid membranes of spinach (Spinacia oleracea L.), which migrates as a green band below CPII on mildly denaturing...

Cross-Linking Patterns in Salt-Extractable Extensin from Carrot Cell Walls 1

Stafstrom, Joel P., Staehelin, L. Andrew

Extensins are hydroxyproline-rich glycoproteins (HRGPs) found in the primary cell walls of dicots. Extensin monomers are secreted into the wall and covalently bound to each other, presumably by...

The Role of Carbohydrate in Maintaining Extensin in an Extended Conformation 1

Stafstrom, Joel P., Staehelin, L. Andrew

Monomers of the plant cell wall glycoprotein extensin are secreted into the wall where they become cross-linked to each other to form a rigid matrix. Expression of the extensin matrix is correlated...

Biochemical Characterization of Photosystem II Antenna Polypeptides in Grana and Stroma Membranes of Spinach 1

Allen, Keith D., Staehelin, L. Andrew

The photosystem (PS) II antenna system comprises several biochemically and spectroscopically distinct complexes, including light-harvesting complex II (LHCII), chlorophyll-protein complex (CP) 29,...

Functional Compartmentation of the Golgi Apparatus of Plant Cells 1: Immunocytochemical Analysis of High-Pressure Frozen- and Freeze-Substituted Sycamore Maple Suspension Culture Cells

Zhang, Guo Feng, Staehelin, L. Andrew

The Golgi apparatus of plant cells is engaged in both the processing of glycoproteins and the synthesis of complex polysaccharides. To investigate the compartmentalization of these functions within...

Redistribution of Golgi Stacks and Other Organelles during Mitosis and Cytokinesis in Plant Cells1[w]

Nebenführ, Andreas, Frohlick, Jennifer A., Staehelin, L. Andrew

We have followed the redistribution of Golgi stacks during mitosis and cytokinesis in living tobacco BY-2 suspension culture cells by means of a green fluorescent protein-tagged soybean α-1,2...

Stop-and-Go Movements of Plant Golgi Stacks Are Mediated by the Acto-Myosin System1

Nebenführ, Andreas, Gallagher, Larry A., Dunahay, Terri G., Frohlick, Jennifer A., Mazurkiewicz, Anna M., Meehl, Janet B., ...

The Golgi apparatus in plant cells consists of a large number of independent Golgi stack/trans-Golgi network/Golgi matrix units that appear to be randomly distributed throughout the cytoplasm. To...

Nodal Endoplasmic Reticulum, a Specialized Form of Endoplasmic Reticulum Found in Gravity-Sensing Root Tip Columella Cells1

Zheng, Hui Qiong, Staehelin, L. Andrew

The endoplasmic reticulum (ER) of columella root cap cells has been postulated to play a role in gravity sensing. We have re-examined the ultrastructure of columella cells in tobacco (Nicotiana...

Amyloplast Sedimentation Dynamics in Maize Columella Cells Support a New Model for the Gravity-Sensing Apparatus of Roots1

Yoder, Thomas L., Zheng, Hui-qiong, Todd, Paul, Staehelin, L. Andrew

Quantitative analysis of statolith sedimentation behavior was accomplished using videomicroscopy of living columella cells of corn (Zea mays) roots, which displayed no systematic cytoplasmic...

Three-Dimensional Analysis of Syncytial-Type Cell Plates during Endosperm Cellularization Visualized by High Resolution Electron Tomography W⃞

Otegui, Marisa S., Mastronarde, David N., Kang, Byung-Ho, Bednarek, Sebastian Y., Staehelin, L. Andrew

The three-dimensional architecture of syncytial-type cell plates in the endosperm of Arabidopsis has been analyzed at ∼6-nm resolution by means of dual-axis high-voltage electron tomography of...

Syncytial-Type Cell Plates: A Novel Kind of Cell Plate Involved in Endosperm Cellularization of Arabidopsis

Otegui, Marisa, Staehelin, L. Andrew

Cell wall formation in the syncytial endosperm of Arabidopsis was studied by using high-pressure-frozen/freeze-substituted developing seeds and immunocytochemical techniques. The endosperm...

Reevaluation of the Effects of Brefeldin A on Plant Cells Using Tobacco Bright Yellow 2 Cells Expressing Golgi-Targeted Green Fluorescent Protein and COPI AntiseraW⃞

Ritzenthaler, Christophe, Nebenführ, Andreas, Movafeghi, Ali, Stussi-Garaud, Christiane, Behnia, Leila, Pimpl, Peter, ...

Brefeldin A (BFA) causes a block in the secretory system of eukaryotic cells by inhibiting vesicle formation at the Golgi apparatus. Although this toxin has been used in many studies, its effects on...

Developing Seeds of Arabidopsis Store Different Minerals in Two Types of Vacuoles and in the Endoplasmic Reticulum

Otegui, Marisa S., Capp, Roberta, Staehelin, L. Andrew

Mineral-accumulating compartments in developing seeds of Arabidopsis were studied using high-pressure-frozen/freeze-substituted samples. Developing seeds store minerals in three locations: in the...

Tomographic Evidence for Continuous Turnover of Golgi Cisternae in Pichia pastorisV⃞

Mogelsvang, Soren, Gomez-Ospina, Natalia, Soderholm, Jon, Glick, Benjamin S., Staehelin, L. Andrew

The budding yeast Pichia pastoris contains ordered Golgi stacks next to discrete transitional endoplasmic reticulum (tER) sites, making this organism ideal for structure–function studies of the...

Supramolecular structure of stacked and unstacked regions of the photosynthetic membranes of Prochloron sp., a prokaryote

Giddings, Thomas H., Withers, Nancy W., Staehelin, L. Andrew

Freeze-fracture replicas of the photosynthetic prokaryote Prochloron sp., collected at Coconut Island, Hawaii, show that the thylakoids are differentiated into stacked and unstacked regions much like...

Electron Tomographic Analysis of Somatic Cell Plate Formation in Meristematic Cells of Arabidopsis Preserved by High-Pressure FreezingW⃞

Seguí-Simarro, José M., Austin, Jotham R., White, Erin A., Staehelin, L. Andrew

We have investigated the process of somatic-type cytokinesis in Arabidopsis (Arabidopsis thaliana) meristem cells with a three-dimensional resolution of ∼7 nm by electron tomography of...

Three Types of Gap Junctions Interconnecting Intestinal Epithelial Cells Visualized by Freeze-Etching

Staehelin, L. Andrew

Gap junctions are specialized membrane regions that seem to mediate intercellular communication. They appear to contain closely packed arrays of equally sized particles all of which, upon...

Does Gibberellic Acid Induce the Transfer of Lipase from Protein Bodies to Lipid Bodies in Barley Aleurone Cells? 1

Fernandez, Donna E., Staehelin, L. Andrew

We have examined the effect of gibberellic acid (GA3) on the distribution of the enzyme responsible for mobilizing storage triacylglycerol in aleurone cells of Hordeum vulgare L. cv Himalaya. Using...

Immunogold Localization of the L3 Protein of Maize Lipid Bodies during Germination and Seedling Growth 1

Fernandez, Donna E., Qu, Rongda, Huang, Anthony H. C., Staehelin, L. Andrew

We have used antibodies directed against the 16.5 kilodalton protein L3, the most abundant integral protein of maize (Zea mays L. cv Mo 17) lipid bodies, to follow the fate of this protein in...

Compensatory Alterations in the Photochemical Apparatus of a Photoregulatory, Chlorophyll b-Deficient Mutant of Maize 1

Greene, Ben A., Staehelin, L. Andrew, Melis, Anastasios

Characterization of the functional organization of the photochemical apparatus in the light sensitive chlorophyll b-deficient oil yellow-yellow green (OY-YG) mutant of maize (Zea mays) is presented....

Immunogold Localization of Xyloglucan and Rhamnogalacturonan I in the Cell Walls of Suspension-Cultured Sycamore Cells 1

Moore, Patricia J., Darvill, Alan G., Albersheim, Peter, Staehelin, L. Andrew

Plant cell walls serve several functions: they impart rigidity to the plant, provide a physical and chemical barrier between the cell and its environment, and regulate the size and shape of each...

A Second Extensin-Like Hydroxyproline-Rich Glycoprotein from Carrot Cell Walls 1

Stafstrom, Joel P., Staehelin, L. Andrew

The insoluble extensin matrix of dicot cell walls has been studied most fruitfully by examining the salt-extractable precursors to this matrix. Multiple extensin-like hydroxyproline-rich...

Lateral Distribution of the Cytochrome b6/f and Coupling Factor ATP Synthetase Complexes of Chloroplast Thylakoid Membranes 1

Allred, David R., Staehelin, L. Andrew

We have visualized directly the distribution of the cytochrome b6/f and coupling factor ATP synthetase complexes in thylakoid membranes of embedded, thin-sectioned, intact chloroplasts by using...

Isolation of Photosystem I Complexes from Octyl Glucoside/Sodium Dodecyl Sulfate Solubilized Spinach Thylakoids 1: Characterization and Reconstitution into Liposomes

Dunahay, Terri G., Staehelin, L. Andrew

We have used the nonionic detergent octyl-β-d-glucopyranoside in combination with sodium dodecyl sulfate to isolate two novel Photosystem I (PSI) complexes from spinach (Spinacea oleracea L.)...

Structure of the Thylakoids and Envelope Membranes of the Cyanelles of Cyanophora paradoxa1

Giddings, Thomas H., Wasmann, Cathy, Staehelin, L. Andrew

The cyanelles of Cyanophora paradoxa Korsch. are photosynthetically active obligate endosymbionts in which phycobiliproteins serve as the major accessory pigments. Freeze-fracture electron...

A Rapid Reverse Phase Evaporation Method for the Reconstitution of Uncharged Thylakoid Membrane Lipids That Resist Hydration 1

Sprague, Sallie G., Staehelin, L. Andrew

Comparison of several lipid reconstitution methods showed that they were not equally efficient at transferring the predominant thylakoid lipid, monogalactosyldiglyceride (MG), to the aqueous phase....

Isolation and Characterization of a New Minor Chlorophyll a/b-Protein Complex (CP24) from Spinach 1

Dunahay, Terri G., Staehelin, L. Andrew

We have identified a new minor chlorophyll a/b-protein complex in the thylakoid membranes of spinach (Spinacia oleracea L.), which migrates as a green band below CPII on mildly denaturing...

Cross-Linking Patterns in Salt-Extractable Extensin from Carrot Cell Walls 1

Stafstrom, Joel P., Staehelin, L. Andrew

Extensins are hydroxyproline-rich glycoproteins (HRGPs) found in the primary cell walls of dicots. Extensin monomers are secreted into the wall and covalently bound to each other, presumably by...

The Role of Carbohydrate in Maintaining Extensin in an Extended Conformation 1

Stafstrom, Joel P., Staehelin, L. Andrew

Monomers of the plant cell wall glycoprotein extensin are secreted into the wall where they become cross-linked to each other to form a rigid matrix. Expression of the extensin matrix is correlated...

Biochemical Characterization of Photosystem II Antenna Polypeptides in Grana and Stroma Membranes of Spinach 1

Allen, Keith D., Staehelin, L. Andrew

The photosystem (PS) II antenna system comprises several biochemically and spectroscopically distinct complexes, including light-harvesting complex II (LHCII), chlorophyll-protein complex (CP) 29,...

Functional Compartmentation of the Golgi Apparatus of Plant Cells 1: Immunocytochemical Analysis of High-Pressure Frozen- and Freeze-Substituted Sycamore Maple Suspension Culture Cells

Zhang, Guo Feng, Staehelin, L. Andrew

The Golgi apparatus of plant cells is engaged in both the processing of glycoproteins and the synthesis of complex polysaccharides. To investigate the compartmentalization of these functions within...

Plastoglobules Are Lipoprotein Subcompartments of the Chloroplast That Are Permanently Coupled to Thylakoid Membranes and Contain Biosynthetic Enzymes

Austin, Jotham R., Frost, Elizabeth, Vidi, Pierre-Alexandre, Kessler, Felix, Staehelin, L. Andrew

Plastoglobules are lipoprotein particles inside chloroplasts. Their numbers have been shown to increase during the upregulation of plastid lipid metabolism in response to oxidative stress and during...

Identification and characterization of COPIa- and COPIb-type vesicle classes associated with plant and algal Golgi

Donohoe, Bryon S., Kang, Byung-Ho, Staehelin, L. Andrew

Coat protein I (COPI) vesicles arise from Golgi cisternae and mediate the recycling of proteins from the Golgi back to the endoplasmic reticulum (ER) and the transport of Golgi resident proteins...

The Proteolytic Processing of Seed Storage Proteins in Arabidopsis Embryo Cells Starts in the Multivesicular Bodies[W]

Otegui, Marisa S., Herder, Rachel, Schulze, Jan, Jung, Rudolf, Staehelin, L. Andrew

We have investigated the transport of storage proteins, their processing proteases, and the Vacuolar Sorting Receptor-1/Epidermal Growth Factor Receptor–Like Protein1 (VSR-1/ATELP1) receptor during...

STRUCTURAL DIFFERENTIATION OF STACKED AND UNSTACKED CHLOROPLAST MEMBRANES : Freeze-Etch Electron Microscopy of Wild-Type and Mutant Strains of Chlamydomonas

Goodenough, Ursula W., Staehelin, L. Andrew

Wild-type chloroplast membranes from Chlamydomonas reinhardi exhibit four faces in freeze-etchreplicas: the complementary Bs and Cs faces are found where the membranes are stacked together; the...

LUMENAL PLASMA MEMBRANE OF THE URINARY BLADDER : I. Three-Dimensional Reconstruction from Freeze-Etch Images

Staehelin, L. Andrew, Chlapowski, Francis J., Bonneville, Mary A.

To determine the three-dimensional structure of the lumenal membrane of transitional epithelium, a study was made of sectioned, negatively stained, and freeze-etched specimens from intact epithelium...

LUMENAL PLASMA MEMBRANE OF THE URINARY BLADDER : II. Isolation and Structure of Membrane Components

Chlapowski, Francis J., Bonneville, Mary A., Staehelin, L. Andrew

A technique has been devised for isolation of lumenal plasma membranes from transitional epithelial cells lining the urinary bladder in rabbits and for subsequent separation of particle-bearing...

EFFECTS OF PHOSPHOTUNGSTATE NEGATIVE STAINING ON THE MORPHOLOGY OF THE ISOLATED GOLGI APPARATUS

Cunningham, William P., Staehelin, L. Andrew, Rubin, Robert W., Wilkins, Ross, Bonneville, Mary

Isolated Golgi complexes can be recognized in phosphotungstate (PTA) negative stain as stacks of membranous plates surrounded by a complex anastomosing network of tubules and vesicles. The extent of...

CILIARY MEMBRANE DIFFERENTIATIONS IN TETRAHYMENA PYRIFORMIS : Tetrahymena Has Four Types of Cilia

Sattler, Carol A., Staehelin, L. Andrew

We have examined thin sections and replicas of freeze-fractured cilia of Tetrahymena pyriformis. The ciliary necklace located at the base of all freeze-fractured oral and somatic cilia has been...

Golgi Structure in Three Dimensions: Functional Insights from the Normal Rat Kidney Cell

Ladinsky, Mark S., Mastronarde, David N., McIntosh, J. Richard, Howell, Kathryn E., Staehelin, L. Andrew

Three-dimensional reconstructions of portions of the Golgi complex from cryofixed, freeze-substituted normal rat kidney cells have been made by dual-axis, high-voltage EM tomography at ∼7-nm...

The Mitochondrial Cycle of Arabidopsis Shoot Apical Meristem and Leaf Primordium Meristematic Cells Is Defined by a Perinuclear Tentaculate/Cage-Like Mitochondrion1[W][OA]

Seguí-Simarro, José M., Coronado, María José, Staehelin, L. Andrew

Plant cells exhibit a high rate of mitochondrial DNA (mtDNA) recombination. This implies that before cytokinesis, the different mitochondrial compartments must fuse to allow for mtDNA intermixing....

Statolith Sedimentation Kinetics and Force Transduction to the Cortical Endoplasmic Reticulum in Gravity-Sensing Arabidopsis Columella Cells[W][OA]

Leitz, Guenther, Kang, Byung-Ho, Schoenwaelder, Monica E.A., Staehelin, L. Andrew

The starch statolith hypothesis of gravity sensing in plants postulates that the sedimentation of statoliths in specialized statocytes (columella cells) provides the means for converting the...

Arabidopsis Protein Disulfide Isomerase-5 Inhibits Cysteine Proteases during Trafficking to Vacuoles before Programmed Cell Death of the Endothelium in Developing Seeds[W]

Andème Ondzighi, Christine, Christopher, David A., Cho, Eun Ju, Chang, Shu-Choeng, Staehelin, L. Andrew

Protein disulfide isomerase (PDI) oxidizes, reduces, and isomerizes disulfide bonds, modulates redox responses, and chaperones proteins. The Arabidopsis thaliana genome contains 12 PDI genes, but...

Mitochondrial reticulation in shoot apical meristem cells of Arabidopsis provides a mechanism for homogenization of mtDNA prior to gamete formation

Seguí-Simarro, José M, Staehelin, L Andrew

Plant mitochondria are typically portrayed as being small, oval organelles. However, a recent study has demonstrated that the chondriome of shoot apical meristem (SAM) cells of Arabidopsis thaliana...