Practical allergy (PRACTALL) report: risk assessment in anaphylaxis. (2008)
Simons, F.E., Frew, A.J., Ansotegui, I.J., Bochner, B.S., Golden, D.B., Finkelman, F.D., ...
Effector mechanisms in anaphylaxis were reviewed. Current approaches to confirmation of the clinical diagnosis were discussed. Improved methods for distinguishing between allergen sensitization...
Mitsui, H, Furitsu, T, Dvorak, A M, Irani, A M, Schwartz, L B, Inagaki, N, ...
Both human and mouse c-kit ligand induced differentiation of human mast cells in a long-term culture of the mononuclear cells of umbilical cord blood. Growth factor activity for human mast cells...
Schwartz, L B, Sakai, K, Bradford, T R, Ren, S, Zweiman, B, Worobec, A S, ...
Tryptase, a protease produced by all mast cells, was evaluated as a clinical marker of systemic mastocytosis. Two sandwich immunoassays were evaluated, one which used the mAb G5 for capture, the...
Cloning and characterization of a second complementary DNA for human tryptase.
Miller, J S, Moxley, G, Schwartz, L B
A second cDNA for human tryptase, called beta-tryptase, was cloned from a mast cell cDNA library in lambda ZAP. Its nucleotide sequence and corresponding amino acid sequence were determined and...
Development of human mast cells in vitro.
Furitsu, T, Saito, H, Dvorak, A M, Schwartz, L B, Irani, A M, Burdick, J F, ...
Nucleated cells of human umbilical cord blood were cocultured with mouse skin-derived 3T3 fibroblasts. After 7-8 weeks in culture, when the number of the other hematopoietic cells declined,...
Schwartz, L B, Yunginger, J W, Miller, J, Bokhari, R, Dull, D
Tryptase, a neutral protease of human mast cells, is a potentially important indicator of mast cell involvement in various clinical conditions. The current study examined the time course of...
Gruber, B L, Marchese, M J, Suzuki, K, Schwartz, L B, Okada, Y, Nagase, H, ...
Mast cells have been implicated in the pathogenesis of the matrix degradation observed in the cartilaginous and osseous structures of the rheumatoid joint. We previously reported that human mast cell...
Two types of human mast cells that have distinct neutral protease compositions.
Irani, A A, Schechter, N M, Craig, S S, DeBlois, G, Schwartz, L B
Two human mast cell types were identified by immunohistochemical techniques in skin, lung, and small intestine. One type contains the neutral proteases, tryptase and chymotryptic proteinase, and is...
Cloning and characterization of complementary DNA for human tryptase.
Miller, J S, Westin, E H, Schwartz, L B
The amino acid sequence of human mast cell tryptase was determined from corresponding cDNA cloned from a lambda ZAP library made with mRNA derived from a human mast cell preparation. Tryptase is the...
Calhoun, W J, Dick, E C, Schwartz, L B, Busse, W W
Many patients with asthma have increased wheezing with colds. We hypothesized that rhinovirus colds might increase asthma by augmenting airway allergic responses (histamine release and eosinophil...
Schwartz, L. B., Lawrence, C., Thach, R. E., Roeder, R. G.
The effect of encephalomyocarditis virus infection of MOPC 460 mouse plasmacytoma cells on host RNA synthesis and RNA polymerases was investigated. Consistent with work performed in other virus host...
Distinct molecular structures of nuclear class I, II, and III DNA-dependent RNA polymerases.
Sklar, V E, Schwartz, L B, Roeder, R G
Class III RNA polymerases purified from the murine plasmacytoma MOPC 315 and from Xenopus laevis ovaries were compared. The subunit structures of the chromatographically distinct murine enzymes IIIA...
Sakai, K, Ren, S, Schwartz, L B
Tryptase is the major protein constituent of human mast cells, where it is stored within the secretory granules as a fully active tetramer. Two tryptase genes (alpha and beta) are expressed by human...
Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor.
Blair, R J, Meng, H, Marchese, M J, Ren, S, Schwartz, L B, Tonnesen, M G, ...
The presence of mast cells near capillary sprouting sites suggests an association between mast cells and angiogenesis. However, the role of mast cells in blood vessel development remains to be...
Harvima, I T, Harvima, R J, Nilsson, G, Ivanoff, L, Schwartz, L B
The V3 loop of the HIV (human immunodeficiency virus)-1 envelope glycoprotein gp120 likely plays a role in HIV-1 infectivity. Although the amino acid sequence of the V3 loop is hypervariable, it...
Alter, S C, Metcalfe, D D, Bradford, T R, Schwartz, L B
Tryptase was previously shown to undergo rapid inactivation under physiological conditions unless stabilized by the presence of heparin. The current study shows that increasing the concentration of...
Two isoenzyme of beta-glucuronidase from a rat basophil leukaemia tumour were co-purified 4067-fold by (NH4)2SO4 precipitation and sequential chromatography on concanavalin A--Sepharose, Sephadex...
Management of abdominal aortic graft complications.
McCann, R L, Schwartz, L B, Georgiade, G S
OBJECTIVE: This study reviews the outcome of 61 patients who underwent 66 reoperations for complications of aortic grafts. There were 25 patients with false aneurysm of an aortic anastomosis and 41...
Chronic ACE inhibition reduces intimal hyperplasia in experimental vein grafts.
O'Donohoe, M K, Schwartz, L B, Radic, Z S, Mikat, E M, McCann, R L, Hagen, P O
Intimal hyperplasia is an important factor in the pathophysiology of vein graft failure. Local renin-angiotensin systems recently have been shown to modulate the development of intimal hyperplasia in...
Mitsui, H, Furitsu, T, Dvorak, A M, Irani, A M, Schwartz, L B, Inagaki, N, ...
Both human and mouse c-kit ligand induced differentiation of human mast cells in a long-term culture of the mononuclear cells of umbilical cord blood. Growth factor activity for human mast cells...
Schwartz, L B, Sakai, K, Bradford, T R, Ren, S, Zweiman, B, Worobec, A S, ...
Tryptase, a protease produced by all mast cells, was evaluated as a clinical marker of systemic mastocytosis. Two sandwich immunoassays were evaluated, one which used the mAb G5 for capture, the...
Cloning and characterization of a second complementary DNA for human tryptase.
Miller, J S, Moxley, G, Schwartz, L B
A second cDNA for human tryptase, called beta-tryptase, was cloned from a mast cell cDNA library in lambda ZAP. Its nucleotide sequence and corresponding amino acid sequence were determined and...
Development of human mast cells in vitro.
Furitsu, T, Saito, H, Dvorak, A M, Schwartz, L B, Irani, A M, Burdick, J F, ...
Nucleated cells of human umbilical cord blood were cocultured with mouse skin-derived 3T3 fibroblasts. After 7-8 weeks in culture, when the number of the other hematopoietic cells declined,...
Schwartz, L B, Yunginger, J W, Miller, J, Bokhari, R, Dull, D
Tryptase, a neutral protease of human mast cells, is a potentially important indicator of mast cell involvement in various clinical conditions. The current study examined the time course of...
Gruber, B L, Marchese, M J, Suzuki, K, Schwartz, L B, Okada, Y, Nagase, H, ...
Mast cells have been implicated in the pathogenesis of the matrix degradation observed in the cartilaginous and osseous structures of the rheumatoid joint. We previously reported that human mast cell...
Two types of human mast cells that have distinct neutral protease compositions.
Irani, A A, Schechter, N M, Craig, S S, DeBlois, G, Schwartz, L B
Two human mast cell types were identified by immunohistochemical techniques in skin, lung, and small intestine. One type contains the neutral proteases, tryptase and chymotryptic proteinase, and is...
Cloning and characterization of complementary DNA for human tryptase.
Miller, J S, Westin, E H, Schwartz, L B
The amino acid sequence of human mast cell tryptase was determined from corresponding cDNA cloned from a lambda ZAP library made with mRNA derived from a human mast cell preparation. Tryptase is the...
Calhoun, W J, Dick, E C, Schwartz, L B, Busse, W W
Many patients with asthma have increased wheezing with colds. We hypothesized that rhinovirus colds might increase asthma by augmenting airway allergic responses (histamine release and eosinophil...
Schwartz, L. B., Lawrence, C., Thach, R. E., Roeder, R. G.
The effect of encephalomyocarditis virus infection of MOPC 460 mouse plasmacytoma cells on host RNA synthesis and RNA polymerases was investigated. Consistent with work performed in other virus host...
Distinct molecular structures of nuclear class I, II, and III DNA-dependent RNA polymerases.
Sklar, V E, Schwartz, L B, Roeder, R G
Class III RNA polymerases purified from the murine plasmacytoma MOPC 315 and from Xenopus laevis ovaries were compared. The subunit structures of the chromatographically distinct murine enzymes IIIA...
Sakai, K, Ren, S, Schwartz, L B
Tryptase is the major protein constituent of human mast cells, where it is stored within the secretory granules as a fully active tetramer. Two tryptase genes (alpha and beta) are expressed by human...
Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor.
Blair, R J, Meng, H, Marchese, M J, Ren, S, Schwartz, L B, Tonnesen, M G, ...
The presence of mast cells near capillary sprouting sites suggests an association between mast cells and angiogenesis. However, the role of mast cells in blood vessel development remains to be...
Harvima, I T, Harvima, R J, Nilsson, G, Ivanoff, L, Schwartz, L B
The V3 loop of the HIV (human immunodeficiency virus)-1 envelope glycoprotein gp120 likely plays a role in HIV-1 infectivity. Although the amino acid sequence of the V3 loop is hypervariable, it...
Alter, S C, Metcalfe, D D, Bradford, T R, Schwartz, L B
Tryptase was previously shown to undergo rapid inactivation under physiological conditions unless stabilized by the presence of heparin. The current study shows that increasing the concentration of...
Two isoenzyme of beta-glucuronidase from a rat basophil leukaemia tumour were co-purified 4067-fold by (NH4)2SO4 precipitation and sequential chromatography on concanavalin A--Sepharose, Sephadex...
Management of abdominal aortic graft complications.
McCann, R L, Schwartz, L B, Georgiade, G S
OBJECTIVE: This study reviews the outcome of 61 patients who underwent 66 reoperations for complications of aortic grafts. There were 25 patients with false aneurysm of an aortic anastomosis and 41...
Chronic ACE inhibition reduces intimal hyperplasia in experimental vein grafts.
O'Donohoe, M K, Schwartz, L B, Radic, Z S, Mikat, E M, McCann, R L, Hagen, P O
Intimal hyperplasia is an important factor in the pathophysiology of vein graft failure. Local renin-angiotensin systems recently have been shown to modulate the development of intimal hyperplasia in...
Irani, A A, Nilsson, G, Ashman, L K, Schwartz, L B
Human fetal liver cells cultured in the presence of recombinant human stem cell factor (rhuSCF) give rise to highly purified mast cell populations. This study examined the effect of steroid hormones...
Irani, A A, Craig, S S, Nilsson, G, Ishizaka, T, Schwartz, L B
Cocultures of dispersed human fetal liver cells with murine Swiss 3T3 fibroblasts resulted in the development of human mast cells after 1 to 4 weeks of culture. Mast cells were detected by...
Phenotypic characterization of stem cell factor-dependent human foetal liver-derived mast cells.
Nilsson, G, Forsberg, K, Bodger, M P, Ashman, L K, Zsebo, K M, Ishizaka, T, ...
Human foetal liver cells are an enriched source of mast cell progenitors that complete their differentiation and mature in response to stem cell factor, the ligand for Kit, in liquid culture. These...
Kliman, H. J., Feinberg, R. F., Schwartz, L. B., Feinman, M. A., Lavi, E., Meaddough, E. L.
Human endometrial glands synthesize and secrete a high molecular weight mucin-like glycoprotein in a menstrual cycle-dependent fashion. A novel moiety within this Golgi-associated glycoprotein is...
Craig, S. S., DeBlois, G., Schwartz, L. B.
A murine monoclonal antibody (G5) against human lung mast cell tryptase was used for selective staining of human mast cells by an indirect immunoperoxidase method. Human tissues (keloid, small bowel,...