Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.
Nielsen, J B, Foor, F, Siekierka, J J, Hsu, M J, Ramadan, N, Morin, N, ...
The immunosuppressants FK506 and rapamycin prevent T-cell activation and also inhibit the growth of certain strains of the yeast Saccharomyces cerevisiae. It has previously been shown that yeast...
Wiederrecht, G, Brizuela, L, Elliston, K, Sigal, N H, Siekierka, J J
FK 506, a powerful immunosuppressant that blocks allograft rejection by preventing T-cell activation, binds to an 11-kDa protein called the FK 506-binding protein (FKBP). Like cyclophilin, a...
Brizuela, L, Draetta, G, Beach, D
p34 kinase, the product of the CDC2 gene, is a cell-cycle regulated protein kinase that is most active during mitosis. In HeLa cells, p34 kinase has previously been shown to exist in both a low- and...
Brizuela, L, Chrebet, G, Bostian, K A, Parent, S A
FK-506 is a novel and potent antagonist of T-cell activation and an inhibitor of fungal growth. Its immunosuppressive activity can be antagonized by the structurally related antibiotic rapamycin, and...
Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase.
Meijer, L, Arion, D, Golsteyn, R, Pines, J, Brizuela, L, Hunt, T, ...
A so-called 'growth-associated' or 'M-phase specific' histone H1 kinase (H1K) has been described in a wide variety of eukaryotic cell types; p34cdc2 has previously been shown to be a catalytic...
Lüscher, B, Brizuela, L, Beach, D, Eisenman, R N
While the p34cdc2 kinase is considered to be a critical regulator of mitosis, its function has not yet been directly linked to one of the key events during the onset of mitosis: nuclear envelope...
p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase.
Brizuela, L, Draetta, G, Beach, D
cdc2+ encodes a protein kinase that is required during both G1 and G2 phases of the cell division cycle in fission yeast. suc1+ is an essential gene that was originally identified as a plasmid-borne...
Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.
Nielsen, J B, Foor, F, Siekierka, J J, Hsu, M J, Ramadan, N, Morin, N, ...
The immunosuppressants FK506 and rapamycin prevent T-cell activation and also inhibit the growth of certain strains of the yeast Saccharomyces cerevisiae. It has previously been shown that yeast...
Wiederrecht, G, Brizuela, L, Elliston, K, Sigal, N H, Siekierka, J J
FK 506, a powerful immunosuppressant that blocks allograft rejection by preventing T-cell activation, binds to an 11-kDa protein called the FK 506-binding protein (FKBP). Like cyclophilin, a...
Brizuela, L, Draetta, G, Beach, D
p34 kinase, the product of the CDC2 gene, is a cell-cycle regulated protein kinase that is most active during mitosis. In HeLa cells, p34 kinase has previously been shown to exist in both a low- and...
Brizuela, L, Chrebet, G, Bostian, K A, Parent, S A
FK-506 is a novel and potent antagonist of T-cell activation and an inhibitor of fungal growth. Its immunosuppressive activity can be antagonized by the structurally related antibiotic rapamycin, and...
Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase.
Meijer, L, Arion, D, Golsteyn, R, Pines, J, Brizuela, L, Hunt, T, ...
A so-called 'growth-associated' or 'M-phase specific' histone H1 kinase (H1K) has been described in a wide variety of eukaryotic cell types; p34cdc2 has previously been shown to be a catalytic...
Lüscher, B, Brizuela, L, Beach, D, Eisenman, R N
While the p34cdc2 kinase is considered to be a critical regulator of mitosis, its function has not yet been directly linked to one of the key events during the onset of mitosis: nuclear envelope...
p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase.
Brizuela, L, Draetta, G, Beach, D
cdc2+ encodes a protein kinase that is required during both G1 and G2 phases of the cell division cycle in fission yeast. suc1+ is an essential gene that was originally identified as a plasmid-borne...