Myocardial damage, inflammation and thrombin inhibition in unstable coronary artery disease (2003)
Oldgren, J, Wallentin, L, Grip, L, Linder, R, Nørgaard, B.L, Siegbahn, A
Aim Unstable coronary artery disease (CAD) is a multifactorial disease involving both thrombotic and inflammatory processes. We have assessed the time-course and the influence of thrombin inhibitors...
Stables, RH, Booth, J, Erbel, R, Wahrborg, P, Lubsen, J, ...
Background Results of trials, comparing percutaneous transluminal coronary angioplasty (PTCA) with coronary artery bypass grafting (CABG), indicate that rates of death or myocardial infarction are...
Results of Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial (2002)
Holmes, D.R. Jr, Granett, J.R., Popma, J., Serruys, P.W., Fitzgerald, P., Fischman, D., ...
BACKGROUND: Restenosis after percutaneous coronary intervention (PCI) is a major problem affecting 15% to 30% of patients after stent placement. No oral agent has shown a beneficial effect on...
Linder, R., Oldgren, J., Egberg, N., Grip, L., Larson, G., Siegbahn, A., ...
Aim This study evaluated a novel specific thrombin inhibitor, inogatran, in comparison with unfractionated heparin, with regard to markers for coagulation activity in patients with unstable coronary...
Näslund, U., Grip, L., Fischer-Hansen, J., Gundersen, T., Lehto, S., Wallentin, L.
Background A multicentre study permits rapid recruitment of a large number of patients. However, there is a risk of heterogeneities in end-point evaluations, as complex definitions of criteria are...
Oldgren, J., Linder, R., Grip, L., Siegbahn, A., Wallentin, L.
Aims Direct thrombin inhibitors have failed to prove superiority over unfractionated heparin in several clinical trials of unstable coronary artery disease. We have investigated the relationship...
Verheugt, F.W.A., Simoons, M.L., Bär, F., Veen, G., ...
Grip, L., Blombäck, M., Egberg, N., Olsson, Å., Svane, B., Velander, M.
Background Thrombin activation may be a higher risk for complications and restenosis after percutaneous transluminal coronary angioplasty in unstable patients than in patients with stable angina...
De Faire, U., Grip, L., Nilsson, J., Svane, B., Hamsten, A.
Current experience from coronary angiographic trials using different treatment regimens such as lifestyle changes, resins, nicotinic acid and statins, shows that progression of atheroma can be...
GRIP, L., BONE, D., HOLMGREN, A., RYDÉN, L.
Perfusion abnormalities and infarct size evaluated by thallium-201 SPECT after late thrombolysis followed by anti-thrombotic treatment in acute myocardial infarction were studied in 111 patients....
GRIP, L., BLOMBÄCK, M., SCHULMAN, S.
Nine out of 47 (19%) patients on chronic anticoagulation with warfarin, as secondary prophylaxis after myocardial infarction, initially treated with streptokinase, had thromboembolic...
GRIP, L., BLOMBÄCK, M., SCHULMAN, S.
Nine out of 47 (19%) patients on chronic anticoagulation with warfarin, as secondary prophylaxis after myocardial infarction, initially treated with streptokinase, had thromboembolic...
Montalescot, G, Andersen, H R, Antoniucci, D, Betriu, A, De Boer, M J, Grip, L, ...
Little information is currently available from the various societies of cardiology on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). Since primary PCI is the...
Nørgaard, B L, Andersen, K, Thygesen, K, Ravkilde, J, Abrahamsson, P, Grip, L, ...
Objective: To examine the long term prognostic characteristics of troponin T testing and continuous multi-lead ST segment monitoring in combination with clinical and 12 lead ECG risk indicators in...