L. Jaap Kappelle

Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study (2009)

Wijman, Christine Ac, Michel, Patrik, Rueckert, Christina M, Weimar, Christian, Mattle, Heinrich P, ...

BACKGROUND: Treatment strategies for acute basilar artery occlusion (BAO) are based on case series and data that have been extrapolated from stroke intervention trials in other cerebrovascular...

Correction: PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN74418480] (2008)

Den Hertog, Heleen M, Worp, H Bart, Algra, Ale, Kappelle, L Jaap, Van Gijn, Jan, ...

Abstract Background The Paracetamol (Acetaminophen) In Stroke (PAIS) study is a phase III multicenter, double blind, randomized, placebo-controlled clinical trial of high-dose acetaminophen in...

A pilot study of rivastigmine in the treatment of delirium after stroke: A safe alternative (2008)

Oldenbeuving, Annemarie W, De Kort, Paul LM, Jansen, Ben PW, Kappelle, L Jaap, Roks, Gerwin

Abstract Background Delirium is a common disorder in the early phase of stroke. Given the presumed cholinergic deficiency in delirium, we tested treatment with the acetylcholinesterase inhibitor...

Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction (2006)

Hofmeijer, Jeannette, Amelink, G Johan, Algra, Ale, Van Gijn, Jan, Macleod, Malcolm R, Kappelle, L Jaap, ...

Abstract Background Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite maximal conservative treatment, the case fatality rate may be as high...

PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN 74418480] (2005)

Van Breda, Eric J, Van Der Worp, H Bart, Algra, Ale, Kappelle, L Jaap, Van Gijn, Jan, ...

Abstract Background In patients with acute stroke, increased body temperature is associated with large lesion volumes, high case fatality, and poor functional outcome. A 1°C increase in body...

Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690] (2003)

Dippel, Diederik WJ, Van Breda, Eric J, Van Der Worp, H Bart, Meijer, Ron J, Kappelle, L Jaap, ...

Abstract Background Body temperature is a strong predictor of outcome in acute stroke. In a previous randomized trial we observed that treatment with high-dose acetaminophen (paracetamol) led to a...

Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690]

Dippel, Diederik WJ, Van Breda, Eric J, Van Der Worp, H Bart, Meijer, Ron J, Kappelle, L Jaap, ...

PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN 74418480]

Van Breda, Eric J, Van Der Worp, H Bart, Algra, Ale, Kappelle, L Jaap, Van Gijn, Jan, ...

Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction

Hofmeijer, Jeannette, Amelink, G Johan, Algra, Ale, Van Gijn, Jan, Macleod, Malcolm R, Kappelle, L Jaap, ...

Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690]

Dippel, Diederik WJ, Van Breda, Eric J, Van Der Worp, H Bart, Meijer, Ron J, Kappelle, L Jaap, ...

PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN 74418480]

Van Breda, Eric J, Van Der Worp, H Bart, Algra, Ale, Kappelle, L Jaap, Van Gijn, Jan, ...

Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction

Hofmeijer, Jeannette, Amelink, G Johan, Algra, Ale, Van Gijn, Jan, Macleod, Malcolm R, Kappelle, L Jaap, ...

A pilot study of rivastigmine in the treatment of delirium after stroke: A safe alternative

Oldenbeuving, Annemarie W, De Kort, Paul LM, Jansen, Ben PW, Kappelle, L Jaap, Roks, Gerwin

Correction: PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN74418480]

Den Hertog, Heleen M, Algra, Ale, Kappelle, L Jaap, Van Gijn, Jan, ...

Bilateral carotid artery occlusion with transient or moderately disabling ischaemic stroke: clinical features and long-term outcome

Persoon, Suzanne, Klijn, Catharina J. M., Algra, Ale, Kappelle, L. Jaap

Information on the prognosis of patients with transient ischaemic attack or moderately disabling ischaemic stroke associated with bilateral internal carotid artery (ICA) occlusion is scarce. We...