L. Jackson Roberts

The Shanghai Women's Asthma and Allergy Study: Objectives, Design, and Recruitment Results (2008)

Hartert, Tina V., Deng, Xinqing, Hartman, Terryl J., Wen, Wanqing, Yang, Gong, Gao, Yu-Tang, ...

The Shanghai Women's Asthma and Allergy Study is the first population-based incidence study designed to assess the associations of dietary antioxidant intake and measures of oxidative stress and...

Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. (1999)

Barlow, Carrolee, Dennery, Phyllis A., Shigenaga, Mark K., Smith, Mark A., Morrow, Jason D., Roberts, L. Jackson, ...

Ataxia-telangiectasia (A-T) is characterized by a markedly increased sensitivity to ionizing radiation, increased incidence of cancer, and neurodegeneration, especially of the cerebellar Purkinje...

Loss of the ataxia–telangiectasia gene product causes oxidative damage in target organs

Barlow, Carrolee, Dennery, Phyllis A., Shigenaga, Mark K., Smith, Mark A., Morrow, Jason D., Roberts, L. Jackson, ...

Ataxia–telangiectasia (A-T) is characterized by a markedly increased sensitivity to ionizing radiation, increased incidence of cancer, and neurodegeneration, especially of the cerebellar Purkinje...

Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension

Fessel, Joshua P., Porter, Ned A., Moore, Kevin P., Sheller, James R., Roberts, L. Jackson

Free radicals have been implicated in the pathogenesis of an increasing number of diseases. Lipids, which undergo peroxidation, are major targets of free radical attack. We report the discovery of a...

Ionophores stimulate prostaglandin and thromboxane biosynthesis*

Knapp, Howard R., Oelz, Oswald, Roberts, L. Jackson, Sweetman, Brian J., Oates, John A., Reed, Peter W.

The role of calcium in triggering prostaglandin and thromboxane synthesis was studied in several systems with ionophores of different ion specificities. Divalent cationophore A23187 stimulates...

Loss of the ataxia–telangiectasia gene product causes oxidative damage in target organs

Barlow, Carrolee, Dennery, Phyllis A., Shigenaga, Mark K., Smith, Mark A., Morrow, Jason D., Roberts, L. Jackson, ...

Ataxia–telangiectasia (A-T) is characterized by a markedly increased sensitivity to ionizing radiation, increased incidence of cancer, and neurodegeneration, especially of the cerebellar Purkinje...

Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension

Fessel, Joshua P., Porter, Ned A., Moore, Kevin P., Sheller, James R., Roberts, L. Jackson

Free radicals have been implicated in the pathogenesis of an increasing number of diseases. Lipids, which undergo peroxidation, are major targets of free radical attack. We report the discovery of a...

Ionophores stimulate prostaglandin and thromboxane biosynthesis*

Knapp, Howard R., Oelz, Oswald, Roberts, L. Jackson, Sweetman, Brian J., Oates, John A., Reed, Peter W.

The role of calcium in triggering prostaglandin and thromboxane synthesis was studied in several systems with ionophores of different ion specificities. Divalent cationophore A23187 stimulates...

Brain Regional Quantification of F-Ring and D-/E-Ring Isoprostanes and Neuroprostanes in Alzheimer’s Disease

Reich, Erin E., Markesbery, William R., Roberts, L. Jackson, Swift, Larry L., Morrow, Jason D., Montine, Thomas J.

Isoprostanes (IsoP) are produced exclusively from free radical damage to arachidonic acid, a fatty acid that is evenly distributed throughout white matter and gray matter, whereas neuroprostanes...