Fluconazole, D0870, and flucytosine treatment of disseminated Candida tropicalis infections in mice.
Graybill, J R, Najvar, L K, Holmberg, J D, Luther, M F
D0870 is a recently developed triazole with characteristics of a broad spectrum of activity and slow clearance by nonrenal mechanisms. Herein we have evaluated the efficacy of D0870, alone and...
Graybill, J R, Najvar, L K, Holmberg, J D, Correa, A, Luther, M F
A series of fluconazole-susceptible and-fluconazole resistant Candida albicans fungal isolates were used to infect mice intravenously. Mice were treated with varying doses of fluconazole beginning...
Barchiesi, F, Najvar, L K, Luther, M F, Scalise, G, Rinaldi, M G, Graybill, J R
Four strains of Candida albicans, isolated from two patients with AIDS who had undergone prolonged fluconazole therapy for oral candidiasis, were studied in a model of disseminated murine...
Combination therapy with fluconazole and flucytosine in the murine model of cryptococcal meningitis.
Nguyen, M H, Najvar, L K, Yu, C Y, Graybill, J R
This study elucidates the role of combined fluconazole and flucytosine as therapy for cryptococcosis in the murine model of meningitis. Three strains of Cryptococcus neoformans for which the range of...
Treatment of murine disseminated candidiasis with L-743,872.
Graybill, J R, Najvar, L K, Luther, M F, Fothergill, A W
L-743,872 (M991), which is a pneumocandin derivative, was evaluated in a mouse model of disseminated candidiasis caused by a fluconazole-resistant isolate of Candida albicans. In immunocompetent mice...
Fluconazole, D0870, and flucytosine treatment of disseminated Candida tropicalis infections in mice.
Graybill, J R, Najvar, L K, Holmberg, J D, Luther, M F
D0870 is a recently developed triazole with characteristics of a broad spectrum of activity and slow clearance by nonrenal mechanisms. Herein we have evaluated the efficacy of D0870, alone and...
Graybill, J R, Najvar, L K, Holmberg, J D, Correa, A, Luther, M F
A series of fluconazole-susceptible and-fluconazole resistant Candida albicans fungal isolates were used to infect mice intravenously. Mice were treated with varying doses of fluconazole beginning...
Barchiesi, F, Najvar, L K, Luther, M F, Scalise, G, Rinaldi, M G, Graybill, J R
Four strains of Candida albicans, isolated from two patients with AIDS who had undergone prolonged fluconazole therapy for oral candidiasis, were studied in a model of disseminated murine...
Combination therapy with fluconazole and flucytosine in the murine model of cryptococcal meningitis.
Nguyen, M H, Najvar, L K, Yu, C Y, Graybill, J R
This study elucidates the role of combined fluconazole and flucytosine as therapy for cryptococcosis in the murine model of meningitis. Three strains of Cryptococcus neoformans for which the range of...
Treatment of murine disseminated candidiasis with L-743,872.
Graybill, J R, Najvar, L K, Luther, M F, Fothergill, A W
L-743,872 (M991), which is a pneumocandin derivative, was evaluated in a mouse model of disseminated candidiasis caused by a fluconazole-resistant isolate of Candida albicans. In immunocompetent mice...