L. Kleiman

Publication List Details

Period

2002 - 2002

Number

31

Co-Authors

The FAA Concept for a Beacon Collision Avoidance Systems (BCAS). Volume I. Executive Summary, (2002)

Koenke, E. J., Kleiman, L., Lucier, E., Schuchman, L., Thedford, W.

A unique airborne aircraft collision avoidance system concept is presented which assures safe separation from the largest possible percentage of potential collision threats. The concept is designed...

Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcription.

Huang, Y, Shalom, A, Li, Z, Wang, J, Mak, J, Wainberg, M A, ...

tRNA(3Lys) is a primer for reverse transcription in human immunodeficiency virus type 1 (HIV-1), and the anticodon of tRNA(3Lys) has been implicated in playing a role in both its placement onto the...

Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site.

Li, X, Quan, Y, Arts, E J, Li, Z, Preston, B D, De Rocquigny, H, ...

Retroviral reverse transcription starts near the 5' end of unspliced viral RNA at a sequence called the primer binding site (PBS), where the tRNA primer anneals to the RNA template for initiation of...

Primer tRNA3Lys on the viral genome exists in unextended and two-base extended forms within mature human immunodeficiency virus type 1.

Huang, Y, Wang, J, Shalom, A, Li, Z, Khorchid, A, Wainberg, M A, ...

In human immunodeficiency virus type 1, tRNALys3 is placed upon the primer binding site, where it serves as the primer for reverse transcription. We show herein that genomic placement occurs...

Mutations in the kissing-loop hairpin of human immunodeficiency virus type 1 reduce viral infectivity as well as genomic RNA packaging and dimerization.

Laughrea, M, Jetté, L, Mak, J, Kleiman, L, Liang, C, Wainberg, M A

A stem-loop termed the kissing-loop hairpin is one of the most highly conserved structures within the leader of human immunodeficiency virus type 1 (HIV-1) and chimpanzee immunodeficiency virus...

Effect of mutations in the nucleocapsid protein (NCp7) upon Pr160(gag-pol) and tRNA(Lys) incorporation into human immunodeficiency virus type 1.

Huang, Y, Khorchid, A, Wang, J, Parniak, M A, Darlix, J L, Wainberg, M A, ...

COS-7 cells were transfected with DNAs containing mutations in the NCp7 sequences of human immunodeficiency virus. Selective incorporation into the virus of tRNA(Lys) was measured by two-dimensional...

The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.

Liang, C, Li, X, Rong, L, Inouye, P, Quan, Y, Kleiman, L, ...

Nucleotide segment (+169)AAAA(+172) constitutes an A-rich loop within human immunodeficiency virus type 1 (HIV-1) (HXB2D) RNA and is able to interact with the anticodon loop (33)/USUU(36) of primer...

Identification of sequences downstream of the primer binding site that are important for efficient replication of human immunodeficiency virus type 1.

Li, X, Liang, C, Quan, Y, Chandok, R, Laughrea, M, Parniak, M A, ...

Reverse transcription of retroviruses is initiated from an 18-nucleotide (nt) primer binding site (PBS), located within the 5' region of viral genomic RNA, to which the host cell-derived tRNA primer...

The roles of the human immunodeficiency virus type 1 Pol protein and the primer binding site in the placement of primer tRNA(3Lys) onto viral genomic RNA.

Liang, C, Rong, L, Morin, N, Cherry, E, Huang, Y, Kleiman, L, ...

Factors that modulate the placement of primer tRNA(3Lys) onto the viral RNA genome in human immunodeficiency virus type 1 (HIV-1) were investigated through analysis of reverse-transcribed products...

Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles.

Mak, J, Jiang, M, Wainberg, M A, Hammarskjöld, M L, Rekosh, D, Kleiman, L

COS-7 cells transfected with human immunodeficiency virus type 1 (HIV-1) proviral DNA produce virus in which three tRNA species are most abundant in the viral tRNA population. These tRNAs have been...

Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication.

Li, X, Mak, J, Arts, E J, Gu, Z, Kleiman, L, Wainberg, M A, ...

The human immunodeficiency virus type 1 genomic RNA primer-binding site (PBS) sequence comprises 18 nucleotides which are complementary to those at the 3' end of the replication initiation primer...

Incorporation of excess wild-type and mutant tRNA(3Lys) into human immunodeficiency virus type 1.

Huang, Y, Mak, J, Cao, Q, Li, Z, Wainberg, M A, Kleiman, L

Human immunodeficiency virus (HIV) particles produced in COS-7 cells transfected with HIV type 1 (HIV-1) proviral DNA contain 8 molecules of tRNA(3Lys) per 2 molecules of genomic RNA and 12 molecules...

Identification of tRNAs incorporated into wild-type and mutant human immunodeficiency virus type 1.

Jiang, M, Mak, J, Ladha, A, Cohen, E, Klein, M, Rovinski, B, ...

We have identified the tRNAs which are incorporated into both wild-type human immunodeficiency virus type 1 strain IIIB (HIV-1IIIB) produced in COS-7 cells transfected with HIV-1 proviral DNA and...

The isolation and measurement of tRNAmeti using RNA/DNA hybridization.

Kleiman, L, Heron, T, Essagian, C, Nicoghosian, K, Cedergren, R J

A pBR322 plasmid containing the initiator tRNAmet gene of Xenopus (pt145 - donated by Stuart Clarkson) will specifically bind to mouse initiator tRNAmet (tRNAmeti) when total mouse tRNA, extracted...

Alterations in lysine transfer RNA during erythroid differentiation of the Friend cell.

Kleiman, L, Woodward-Jack, J, Cedergren, R J, Dion, R

The proportion of lysine tRNA represented by the isoacceptor species lysine tRNA4 has previously been shown to be largest in cells with the greatest ability to proliferate. Using reverse phase...

Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcription.

Huang, Y, Shalom, A, Li, Z, Wang, J, Mak, J, Wainberg, M A, ...

tRNA(3Lys) is a primer for reverse transcription in human immunodeficiency virus type 1 (HIV-1), and the anticodon of tRNA(3Lys) has been implicated in playing a role in both its placement onto the...

Human immunodeficiency virus Type 1 nucleocapsid protein (NCp7) directs specific initiation of minus-strand DNA synthesis primed by human tRNA(Lys3) in vitro: studies of viral RNA molecules mutated in regions that flank the primer binding site.

Li, X, Quan, Y, Arts, E J, Li, Z, Preston, B D, De Rocquigny, H, ...

Retroviral reverse transcription starts near the 5' end of unspliced viral RNA at a sequence called the primer binding site (PBS), where the tRNA primer anneals to the RNA template for initiation of...

Primer tRNA3Lys on the viral genome exists in unextended and two-base extended forms within mature human immunodeficiency virus type 1.

Huang, Y, Wang, J, Shalom, A, Li, Z, Khorchid, A, Wainberg, M A, ...

In human immunodeficiency virus type 1, tRNALys3 is placed upon the primer binding site, where it serves as the primer for reverse transcription. We show herein that genomic placement occurs...

Mutations in the kissing-loop hairpin of human immunodeficiency virus type 1 reduce viral infectivity as well as genomic RNA packaging and dimerization.

Laughrea, M, Jetté, L, Mak, J, Kleiman, L, Liang, C, Wainberg, M A

A stem-loop termed the kissing-loop hairpin is one of the most highly conserved structures within the leader of human immunodeficiency virus type 1 (HIV-1) and chimpanzee immunodeficiency virus...

Effect of mutations in the nucleocapsid protein (NCp7) upon Pr160(gag-pol) and tRNA(Lys) incorporation into human immunodeficiency virus type 1.

Huang, Y, Khorchid, A, Wang, J, Parniak, M A, Darlix, J L, Wainberg, M A, ...

COS-7 cells were transfected with DNAs containing mutations in the NCp7 sequences of human immunodeficiency virus. Selective incorporation into the virus of tRNA(Lys) was measured by two-dimensional...

The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.

Liang, C, Li, X, Rong, L, Inouye, P, Quan, Y, Kleiman, L, ...

Nucleotide segment (+169)AAAA(+172) constitutes an A-rich loop within human immunodeficiency virus type 1 (HIV-1) (HXB2D) RNA and is able to interact with the anticodon loop (33)/USUU(36) of primer...

Identification of sequences downstream of the primer binding site that are important for efficient replication of human immunodeficiency virus type 1.

Li, X, Liang, C, Quan, Y, Chandok, R, Laughrea, M, Parniak, M A, ...

Reverse transcription of retroviruses is initiated from an 18-nucleotide (nt) primer binding site (PBS), located within the 5' region of viral genomic RNA, to which the host cell-derived tRNA primer...

The roles of the human immunodeficiency virus type 1 Pol protein and the primer binding site in the placement of primer tRNA(3Lys) onto viral genomic RNA.

Liang, C, Rong, L, Morin, N, Cherry, E, Huang, Y, Kleiman, L, ...

Factors that modulate the placement of primer tRNA(3Lys) onto the viral RNA genome in human immunodeficiency virus type 1 (HIV-1) were investigated through analysis of reverse-transcribed products...

Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particles.

Mak, J, Jiang, M, Wainberg, M A, Hammarskjöld, M L, Rekosh, D, Kleiman, L

COS-7 cells transfected with human immunodeficiency virus type 1 (HIV-1) proviral DNA produce virus in which three tRNA species are most abundant in the viral tRNA population. These tRNAs have been...

Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication.

Li, X, Mak, J, Arts, E J, Gu, Z, Kleiman, L, Wainberg, M A, ...

The human immunodeficiency virus type 1 genomic RNA primer-binding site (PBS) sequence comprises 18 nucleotides which are complementary to those at the 3' end of the replication initiation primer...

Incorporation of excess wild-type and mutant tRNA(3Lys) into human immunodeficiency virus type 1.

Huang, Y, Mak, J, Cao, Q, Li, Z, Wainberg, M A, Kleiman, L

Human immunodeficiency virus (HIV) particles produced in COS-7 cells transfected with HIV type 1 (HIV-1) proviral DNA contain 8 molecules of tRNA(3Lys) per 2 molecules of genomic RNA and 12 molecules...

Identification of tRNAs incorporated into wild-type and mutant human immunodeficiency virus type 1.

Jiang, M, Mak, J, Ladha, A, Cohen, E, Klein, M, Rovinski, B, ...

We have identified the tRNAs which are incorporated into both wild-type human immunodeficiency virus type 1 strain IIIB (HIV-1IIIB) produced in COS-7 cells transfected with HIV-1 proviral DNA and...

The isolation and measurement of tRNAmeti using RNA/DNA hybridization.

Kleiman, L, Heron, T, Essagian, C, Nicoghosian, K, Cedergren, R J

A pBR322 plasmid containing the initiator tRNAmet gene of Xenopus (pt145 - donated by Stuart Clarkson) will specifically bind to mouse initiator tRNAmet (tRNAmeti) when total mouse tRNA, extracted...

Alterations in lysine transfer RNA during erythroid differentiation of the Friend cell.

Kleiman, L, Woodward-Jack, J, Cedergren, R J, Dion, R

The proportion of lysine tRNA represented by the isoacceptor species lysine tRNA4 has previously been shown to be largest in cells with the greatest ability to proliferate. Using reverse phase...