Escherichia coli B/r leuK mutant lacking pseudouridine synthase I activity.
Searles, L L, Jones, J W, Fournier, M J, Grambow, N, Tyler, B, Calvo, J M
Escherichia coli B/r strain EB146 containing mutation leuK16 has elevated levels of enzymes involved in the synthesis of leucine, valine, isoleucine, histidine, and tryptophan (Brown et al., J....
Murray, M V, Turnage, M A, Williamson, K J, Steinhauer, W R, Searles, L L
Mutations of the Drosophila melanogaster suppressor of sable [su(s)] gene, which encodes a 150-kDa nuclear protein [Su(s)], increase the accumulation of specific transcripts in a manner that is not...
Molecular characterization of the Drosophila vermilion locus and its suppressible alleles.
We have cloned vermilion (v), one of the genes required for brown eye pigment synthesis in Drosophila, using a mutant (vH2a) "tagged" with the transposon P factor. Mutations that disrupt v gene...
Recessive mutations of the Drosophila melanogaster suppressor of sable [su(s)] gene result in elevated accumulation of RNA from vermilion (v) mutant alleles that have an insertion of the 7.5-kb...
Transcriptional regulation of the TATA-less promoter of the Drosophila melanogaster vermilion (v) gene was investigated. Developmental Northern (RNA) blot analysis showed that v transcripts...
Searles, L L, Ruth, R S, Pret, A M, Fridell, R A, Ali, A J
The nucleotide sequence and intron-exon structure of the Drosophila melanogaster vermilion (v) gene have been determined. In addition, the sites of several mutations and the effects of these...
Searles, L L, Greenleaf, A L, Kemp, W E, Voelker, R A
Several P element insertion and deletion mutations near the 5' end of Drosophila melanogaster RpII215 have been examined by nucleotide sequencing. Two different sites of P element insertion,...
Sequence Analysis of N-Ethyl-N-Nitrosourea-Induced Vermilion Mutations in Drosophila Melanogaster
Pastink, A., Vreeken, C., Nivard, MJM., Searles, L. L., Vogel, E. W.
The mutational specificity of N-ethyl-N-nitrosourea (ENU) was determined in Drosophila melanogaster using the vermilion locus as a target gene. 25 mutants (16 F(1) and 9 F(2) mutants) were cloned and...
A mutation of the Drosophila melanogaster vermilion (v) gene known as v(1) is caused by the insertion of a 412 retrotransposon into the 5' untranslated region of the first exon. Mutants carrying this...
Sass, G. L., Mohler, J. D., Walsh, R. C., Kalfayan, L. J., Searles, L. L.
Mutations at the ovarian tumor (otu) gene of Drosophila melanogaster cause female sterility and generate a range of ovarian phenotypes. Quiescent (QUI) mutants exhibit reduced germ cell...
Escherichia coli B/r leuK mutant lacking pseudouridine synthase I activity.
Searles, L L, Jones, J W, Fournier, M J, Grambow, N, Tyler, B, Calvo, J M
Escherichia coli B/r strain EB146 containing mutation leuK16 has elevated levels of enzymes involved in the synthesis of leucine, valine, isoleucine, histidine, and tryptophan (Brown et al., J....
Murray, M V, Turnage, M A, Williamson, K J, Steinhauer, W R, Searles, L L
Mutations of the Drosophila melanogaster suppressor of sable [su(s)] gene, which encodes a 150-kDa nuclear protein [Su(s)], increase the accumulation of specific transcripts in a manner that is not...
Molecular characterization of the Drosophila vermilion locus and its suppressible alleles.
We have cloned vermilion (v), one of the genes required for brown eye pigment synthesis in Drosophila, using a mutant (vH2a) "tagged" with the transposon P factor. Mutations that disrupt v gene...
Recessive mutations of the Drosophila melanogaster suppressor of sable [su(s)] gene result in elevated accumulation of RNA from vermilion (v) mutant alleles that have an insertion of the 7.5-kb...
Transcriptional regulation of the TATA-less promoter of the Drosophila melanogaster vermilion (v) gene was investigated. Developmental Northern (RNA) blot analysis showed that v transcripts...
Searles, L L, Ruth, R S, Pret, A M, Fridell, R A, Ali, A J
The nucleotide sequence and intron-exon structure of the Drosophila melanogaster vermilion (v) gene have been determined. In addition, the sites of several mutations and the effects of these...
Searles, L L, Greenleaf, A L, Kemp, W E, Voelker, R A
Several P element insertion and deletion mutations near the 5' end of Drosophila melanogaster RpII215 have been examined by nucleotide sequencing. Two different sites of P element insertion,...
Sequence Analysis of N-Ethyl-N-Nitrosourea-Induced Vermilion Mutations in Drosophila Melanogaster
Pastink, A., Vreeken, C., Nivard, MJM., Searles, L. L., Vogel, E. W.
The mutational specificity of N-ethyl-N-nitrosourea (ENU) was determined in Drosophila melanogaster using the vermilion locus as a target gene. 25 mutants (16 F(1) and 9 F(2) mutants) were cloned and...
A mutation of the Drosophila melanogaster vermilion (v) gene known as v(1) is caused by the insertion of a 412 retrotransposon into the 5' untranslated region of the first exon. Mutants carrying this...
Sass, G. L., Mohler, J. D., Walsh, R. C., Kalfayan, L. J., Searles, L. L.
Mutations at the ovarian tumor (otu) gene of Drosophila melanogaster cause female sterility and generate a range of ovarian phenotypes. Quiescent (QUI) mutants exhibit reduced germ cell...