L. R. Gahan

Publication List Details

Period

1997 - 2008

Number

111

Co-Authors

The Reaction Mechanism of the Ga(III)Zn(II) Derivative of Uteroferrin and Corresponding Biomimetics (2007)

Smith, S. J., Casellato, A., Hadler, K. S., Mitic, N., Riley, M. J., Bortoluzzi, A. J., ...

Purple acid phosphatase from pig uterine fluid (uteroferrin), a representative of the diverse family of binuclear metallohydrolases, requires a heterovalent Fe(III)Fe(II) center for catalytic...

Diesterase activity and substrate binding in purple acid phosphatases (2007)

Cox, R. S., Schenk, G., Mitic, N., Gahan, L. R., Hengge, A. C.

The purple acid phosphatases (PAPs) are bimetallophosphatases that are reported to lack phosphodiesterase activity based on the absence of reactivity with bis(p-nitrophenyl) phosphate. Yet, model...

Diesterase activity and substrate binding in purple acid phosphatases (2007)

Cox, R. S., Schenk, G., Mitic, N., Gahan, L. R., Hengge, A. C.

The purple acid phosphatases (PAPs) are bimetallophosphatases that are reported to lack phosphodiesterase activity based on the absence of reactivity with bis(p-nitrophenyl) phosphate. Yet, model...

The Reaction Mechanism of the Ga(III)Zn(II) Derivative of Uteroferrin and Corresponding Biomimetics (2007)

Smith, S. J., Casellato, A., Hadler, K. S., Mitic, N., Riley, M. J., Bortoluzzi, A. J., ...

Purple acid phosphatase from pig uterine fluid (uteroferrin), a representative of the diverse family of binuclear metallohydrolases, requires a heterovalent Fe(III)Fe(II) center for catalytic...

Surface-Functionalized Polymer Nanoparticles for Selective Sequestering of Heavy Metals (2006)

C. A. Bell, S. V. Smith, M. R. Whittaker, A. K. Whittaker, L. R. Gahan, M. J. Monteiro

This is the highest impact factor journal (8.078) for Material Science. The work involves the synthesis of polymer nanoparticles with functional surfaces and polymer chemical composition for...

Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism (2006)

Elliott, T. W., Mitic, N., Gahan, L. R., Guddat, L. W., Schenk, G.

Purple acid phosphatases (PAPs) belong to the family of binuclear metallohydrolases and catalyse the hydrolysis of a large group of phosphoester substrates at acidic pH. Despite structural...

Surface-Functionalized Polymer Nanoparticles for Selective Sequestering of Heavy Metals (2006)

C. A. Bell, S. V. Smith, M. R. Whittaker, A. K. Whittaker, L. R. Gahan, M. J. Monteiro

This is the highest impact factor journal (8.078) for Material Science. The work involves the synthesis of polymer nanoparticles with functional surfaces and polymer chemical composition for...

Surface-functionalized polymer nanoparticles for selective sequestering of heavy metals (2006)

Bell, C. A., Smith, S. V., Whittaker, M. R., Whittaker, A. K., Gahan, L. R., Monteiro, M. J.

Xanthate-mediated (reversible addition-fragmentation chain transfer) emulsion polymerization has been used to create novel polystyrene nanoparticles with functionalized surfaces (see Figure) for the...

Surface-functionalized polymer nanoparticles for selective sequestering of heavy metals (2006)

Bell, C. A., Smith, S. V., Whittaker, M. R., Whittaker, A. K., Gahan, L. R., Monteiro, M. J.

Xanthate-mediated (reversible addition-fragmentation chain transfer) emulsion polymerization has been used to create novel polystyrene nanoparticles with functionalized surfaces (see Figure) for the...

Inhibition studies of purple acid phosphatases: Implications for the catalytic mechanism (2006)

Elliott, T. W., Mitic, N., Gahan, L. R., Guddat, L. W., Schenk, G.

Purple acid phosphatases (PAPs) belong to the family of binuclear metallohydrolases and catalyse the hydrolysis of a large group of phosphoester substrates at acidic pH. Despite structural...

Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase (2005)

Schenk, G., Gahan, L. R., Carrington, L. E., Mitic, N., Valizadeh, M., Hamilton, S. E., ...

Purple acid phosphatases (PAPs) are a family of binuclear metalloenzymes that catalyze the hydrolysis of phosphoric acid esters and anhydrides. A PAP in sweet potato has a unique, strongly...

A new heterobinuclear (FeCuII)-Cu-III complex with a single terminal Fe-III-O(phenolate) bond. Relevance to purple acid phosphatases and nucleases (2005)

Lanznaster, M., Neves, A., Bortoluzzi, A. J., Aires, VV. E., Szpoganicz, B., Terenzi, H., ...

A novel heterobinuclear mixed valence complex [Fe-III Cu-II(BPBPMP)(OAc)(2)] ClO4, 1, with the unsymmetrical N5O2 donor ligand 2-bis[{(2-pyridylmethyl)...

Synthetic, EPR spectroscopic, magnetic and X-ray crystallographic structural studies on copper(II) complexes of the tridentate N2S donor ligand formed from 6-methyl-2-formylpyridine and S-methyldithiocarbazate (Hmpsme) (2005)

Ali, M. A., Mirza, A. H., Fereday, R. J., Butcher, R. J., Fuller, J. M., Drew, S. C., ...

New copper(II) complexes of general empirical formula, Cu(mpsme)X center dot xCH(3)COCH(3) (mpsme = anionic form of the 6-methyl-2-formylpyridine Schiff base of S-methyldithiocarbazate; X = Cl, N-3,...

Phosphate forms an unusual tripodal complex with the Fe-Mn center of sweet potato purple acid phosphatase (2005)

Schenk, G., Gahan, L. R., Carrington, L. E., Mitic, N., Valizadeh, M., Hamilton, S. E., ...

Purple acid phosphatases (PAPs) are a family of binuclear metalloenzymes that catalyze the hydrolysis of phosphoric acid esters and anhydrides. A PAP in sweet potato has a unique, strongly...

Synthetic, EPR spectroscopic, magnetic and X-ray crystallographic structural studies on copper(II) complexes of the tridentate N2S donor ligand formed from 6-methyl-2-formylpyridine and S-methyldithiocarbazate (Hmpsme) (2005)

Ali, M. A., Mirza, A. H., Fereday, R. J., Butcher, R. J., Fuller, J. M., Drew, S. C., ...

New copper(II) complexes of general empirical formula, Cu(mpsme)X center dot xCH(3)COCH(3) (mpsme = anionic form of the 6-methyl-2-formylpyridine Schiff base of S-methyldithiocarbazate; X = Cl, N-3,...

Formation of Mononuclear and Chlorobridged Binuclear Copper(II) Complexes of Patellamide D, a Naturally Occurring Cyclic Peptide: Influence of Anion and Solvent (2004)

Van Den Brenk, A. L, Tyndall, J. D. A, Cusack, R. M, Jones, A, Fairlie, D. P, Gahan, L. R, ...

This is one of a series of ten papers reporting aspects of the chemistry of cyclic peptides of marine origin. All reported significant results regarding the binding of metal ions. Here the binding of...

Formation of Mononuclear and Chlorobridged Binuclear Copper(II) Complexes of Patellamide D, a Naturally Occurring Cyclic Peptide: Influence of Anion and Solvent (2004)

Van Den Brenk, A. L, Tyndall, J. D. A, Cusack, R. M, Jones, A, Fairlie, D. P, Gahan, L. R, ...

This is one of a series of ten papers reporting aspects of the chemistry of cyclic peptides of marine origin. All reported significant results regarding the binding of metal ions. Here the binding of...

Embracing ligands. Synthesis, characterisation and the correlation between 59Co NMR and ligand field parameters of Co(III) complexes with a new class of nitrogen-thioether multidentate ligand (2004)

Sharrad, C. A., Cavigliasso, G. E., Stranger, R., Gahan, L. R.

The syntheses of the hexadentate ligands 2,2,10,10-tetra(methyleneamine)-4,8-dithiaundecane (PrN(4)S(2)amp), 2,2,11,11-tetra(methyleneamine)-4,9-dithiadodecane (BuN(4)S(2)amp), and...

Synthesis and characterization of cobalt(III) complexes with sinambic amplector ligands (2004)

Sharrad, C. A., Gahan, L. R.

The synthesis of the hexadentate ligand 5,6-dimethyl-2,2,9,9-tetra(methyleneamine)-4,7-dithiadecane (1,2-Me(2)EtN(4)S(2)amp) is reported. The diastereiosomers were separated as cobalt(III) complexes...

Embracing ligands. Synthesis, characterisation and the correlation between 59Co NMR and ligand field parameters of Co(III) complexes with a new class of nitrogen-thioether multidentate ligand (2004)

Sharrad, C. A., Cavigliasso, G. E., Stranger, R., Gahan, L. R.

The syntheses of the hexadentate ligands 2,2,10,10-tetra(methyleneamine)-4,8-dithiaundecane (PrN(4)S(2)amp), 2,2,11,11-tetra(methyleneamine)-4,9-dithiadodecane (BuN(4)S(2)amp), and...

Synthesis and characterization of cobalt(III) complexes with sinambic amplector ligands (2004)

Sharrad, C. A., Gahan, L. R.

The synthesis of the hexadentate ligand 5,6-dimethyl-2,2,9,9-tetra(methyleneamine)-4,7-dithiadecane (1,2-Me(2)EtN(4)S(2)amp) is reported. The diastereiosomers were separated as cobalt(III) complexes...

Piezoelectric Metal Biosensors (2003)

Raymond, K. N., Hawkins, C. J., Gahan, L. R.

We have investigated the response of 10 MHz AT-cut Ag electroded piezoelectric crystals to aqueous NaCl solutions (concentration 0.5 to 1.0 mM) and found that the frequency change is linear in this...

Studies of the interaction of Potassium(I), Calcium(II), Magnesium(II), and Copper(II) with Cyclosporin A (2003)

Cusack, R., Grondahl, L., Fairlie, D., Hanson, G. R., Gahan, L. R.

Metal ion binding properties of the immunosuppressant drug cyclosporin A have been investigated. Complexation studies in acetonitrile solution using H-1 NMR and CD spectroscopy yielded 1:1...

Studies of the interaction of Potassium(I), Calcium(II), Magnesium(II), and Copper(II) with Cyclosporin A (2003)

Cusack, R., Grondahl, L., Fairlie, D., Hanson, G. R., Gahan, L. R.

Metal ion binding properties of the immunosuppressant drug cyclosporin A have been investigated. Complexation studies in acetonitrile solution using H-1 NMR and CD spectroscopy yielded 1:1...

Cyclic octapeptides containing thiazole. Effect of stereochemistry and degree of flexibility on calcium binding properties (2002)

Cusack, R. M., Grondahl, L., Fairlie, D. P., Gahan, L. R., Hanson, G. R.

Solution conformation and calcium binding properties have been investigated for the two cyclic octapeptides cyclo(-D-Thr-D-Val(Thz)-Ile-)(2) (4) and cyclo(-Thr-Gly(Thz)-Ile-Ser-Gly(Thz)-Ile-)(5) and...

Synthesis and structural properties of patellamide a derivatives and their copper(II) compounds (2002)

Bernhardt, P. V., Comba, P., Fairlie, D. P., Gahan, L. R., Hanson, G. R., Lotzbeyer, L.

The synthesis, characterization and copper(II) coordination chemistry of three new cyclic peptide ligands, PatJ(1) (cyclo-(Ile -Thr- (Gly)Thz-lle-Thr(Gly)Thz)), PatJ(2)...

Characterization of [Fe(AMN3S3sarH)]3+ - a rigorously low-spin iron(II) complex (2002)

Sharrad, C. A., Gahan, L. R.

The iron(II) complex [Fe(AMN(3)S(3)sarH)](ClO4)(3).3H(2)O (AMN(3)S(3)sarH = 8-ammonio-1-methyl-3,13,16-trithia-6,10,19-triazabicyclo[6.6.6]icosane) has been synthesized and characterized by single...

Cyclic octapeptides containing thiazole. Effect of stereochemistry and degree of flexibility on calcium binding properties (2002)

Cusack, R. M., Grondahl, L., Fairlie, D. P., Gahan, L. R., Hanson, G. R.

Solution conformation and calcium binding properties have been investigated for the two cyclic octapeptides cyclo(-D-Thr-D-Val(Thz)-Ile-)(2) (4) and cyclo(-Thr-Gly(Thz)-Ile-Ser-Gly(Thz)-Ile-)(5) and...

Synthesis and structural properties of patellamide a derivatives and their copper(II) compounds (2002)

Bernhardt, P. V., Comba, P., Fairlie, D. P., Gahan, L. R., Hanson, G. R., Lotzbeyer, L.

The synthesis, characterization and copper(II) coordination chemistry of three new cyclic peptide ligands, PatJ(1) (cyclo-(Ile -Thr- (Gly)Thz-lle-Thr(Gly)Thz)), PatJ(2)...

Characterization of [Fe(AMN3S3sarH)]3+ - a rigorously low-spin iron(II) complex (2002)

Sharrad, C. A., Gahan, L. R.

The iron(II) complex [Fe(AMN(3)S(3)sarH)](ClO4)(3).3H(2)O (AMN(3)S(3)sarH = 8-ammonio-1-methyl-3,13,16-trithia-6,10,19-triazabicyclo[6.6.6]icosane) has been synthesized and characterized by single...

Determination of the stability constants of mercury(II) complexes of mixed donor macrobicyclic encapsulating ligands (2001)

Sharrad, C. A., Grondahl, L., Gahan, L. R.

The reactions of mercury(II) with the mixed donor encapsulating ligands 3,6,16-trithia-6,11,19-triazabicyclo[6.6.6]icosane (AMN(3)S(3)sar) and...

Separation of mercury (II), lead (II), and silver (I) from aqueous solution using an aminopolycarboxylate silica (2001)

Cox, M. T., Gahan, L. R.

A quartz crystal microbalance modified by the attachment of silica particles derivatized with the aminopolycarboxylate ligand N-[(3-trimethoxysilyl)propyl]ethylenediamine-N,N',N'-triacetic acid has...

Novel Cylindrical, Conical, and Macrocyclic Peptides from the Cyclooligomerization of Functionalized Thiazole Amino Acids (2001)

Singh, Y., Sokolenko, N., Kelso, M. J., Gahan, L. R., Abbenante, G., Fairlie, D. P.

This is one of a series of ten papers reporting aspects of the chemistry of cyclic peptides of marine origin. All reported significant results regarding the binding of metal ions. Here the structural...

Determination of the stability constants of mercury(II) complexes of mixed donor macrobicyclic encapsulating ligands (2001)

Sharrad, C. A., Grondahl, L., Gahan, L. R.

The reactions of mercury(II) with the mixed donor encapsulating ligands 3,6,16-trithia-6,11,19-triazabicyclo[6.6.6]icosane (AMN(3)S(3)sar) and...

Separation of mercury (II), lead (II), and silver (I) from aqueous solution using an aminopolycarboxylate silica (2001)

Cox, M. T., Gahan, L. R.

A quartz crystal microbalance modified by the attachment of silica particles derivatized with the aminopolycarboxylate ligand N-[(3-trimethoxysilyl)propyl]ethylenediamine-N,N',N'-triacetic acid has...

Novel Cylindrical, Conical, and Macrocyclic Peptides from the Cyclooligomerization of Functionalized Thiazole Amino Acids (2001)

Singh, Y., Sokolenko, N., Kelso, M. J., Gahan, L. R., Abbenante, G., Fairlie, D. P.

This is one of a series of ten papers reporting aspects of the chemistry of cyclic peptides of marine origin. All reported significant results regarding the binding of metal ions. Here the structural...

Conformations of cyclic octapeptides and the influence of heterocyclic ring constraints upon calcium binding (2000)

Cusack, R. M., Grondahl, L., Abbenante, G., Fairlie, D. P., Gahan, L. R., Hanson, G. R., ...

A comparison is made between the structures and calcium binding properties of four cyclic octapeptides that differ in the number of heterocyclic thiazole and oxazoline ring constraints. The...

Conformations of cyclic octapeptides and the influence of heterocyclic ring constraints upon calcium binding (2000)

Cusack, R. M., Grondahl, L., Abbenante, G., Fairlie, D. P., Gahan, L. R., Hanson, G. R., ...

A comparison is made between the structures and calcium binding properties of four cyclic octapeptides that differ in the number of heterocyclic thiazole and oxazoline ring constraints. The...

Interaction of zinc(II) with the cyclic octapeptides, cyclo[Ile(Oxn)-D-Val(Thz)](2) and ascidiacyclamide, a cyclic peptide from Lissoclinum patella (1999)

Grondahl, L., Sokolenko, N., Abbenante, G., Fairlie, D. P., Hanson, G. R., Gahan, L. R.

The interactions between zinc salts and the naturally occurring cyclic octapeptide ascidiacyclamide in methanol, as well as a synthetic analogue cyclo[Ile(Oxn)-D-Val(Thz)](2), were monitored by H-1...

Complexes of 1-thia-4,7,10-triazacyclododecane ([12]aneN(3)S) - Synthesis, structure and stability constants (1999)

Marcus, S., Bernhardt, P. V., Grondahl, L., Gahan, L. R.

The 12-membered macrocyclic ligand 1-thia-4,7, 10-triazacyclododecane ([12]aneN(3)S) has been synthesised, although upon crystallization from acetonitrile a product in which carbon dioxide had added...

Mercury(II) and lead (II) complexes of 1-Oxa-7-thia-4,10-diazacyclododecane ([12]aneN2OS) (1999)

Afshar, S., Marcus, S., Gahan, L. R., Hambley, T. W.

The mixed donor 12-membered macrocyclic ligand 1-oxa-7-thia-4,10-diazacyclododecane ([12]aneN2OS) has been synthesized and the mercury(II) and lead(II) complexes, [Hg([12]aneN2OS)(NO3)2] and...

Nickel complexes with tris(2-aminoethyl)amine (tren): [Ni3(tren)4(H2O)2][Cr(ox)3]2.6H2O, {[Ni2(tren)3][ClO4]4.H2O}n, and [Ni2(tren)2(aepd)][ClO4]4.2H2O.Synthesis, structure and magnetism (1999)

Masters, V., Bernhardt, P. V., Gahan, L. R., Moubaraki, B., Murray, K. S., Berry, K. J.

Reaction of K3[Cr(ox)3] (ox = oxalate) with nickel(II) and tris(2-aminoethyl)amine (tren) in aqueous solution resulted in isolation of the bimetallic assembly [Ni3(tren)4(H2O)2][Cr(ox)3]2ยท6H2O. The...

Detection of lead(II) and silver(I) in aqueous solution using a piezoelectric device (1999)

Cox, M., Hill, L. M., Gahan, L. R.

The gold surface of a quartz crystal microbalance was modified by the attachment of silica particles derivatised with N-[(3-trimethoxysilyl)propyl] ethylenediaminetriacetic acid. The device was...

Interaction of zinc(II) with the cyclic octapeptides, cyclo[Ile(Oxn)-D-Val(Thz)](2) and ascidiacyclamide, a cyclic peptide from Lissoclinum patella (1999)

Grondahl, L., Sokolenko, N., Abbenante, G., Fairlie, D. P., Hanson, G. R., Gahan, L. R.

The interactions between zinc salts and the naturally occurring cyclic octapeptide ascidiacyclamide in methanol, as well as a synthetic analogue cyclo[Ile(Oxn)-D-Val(Thz)](2), were monitored by H-1...

Detection of lead(II) and silver(I) in aqueous solution using a piezoelectric device (1999)

Cox, M., Hill, L. M., Gahan, L. R.

The gold surface of a quartz crystal microbalance was modified by the attachment of silica particles derivatised with N-[(3-trimethoxysilyl)propyl] ethylenediaminetriacetic acid. The device was...

Complexes of 1-thia-4,7,10-triazacyclododecane ([12]aneN(3)S) - Synthesis, structure and stability constants (1999)

Marcus, S., Bernhardt, P. V., Grondahl, L., Gahan, L. R.

The 12-membered macrocyclic ligand 1-thia-4,7, 10-triazacyclododecane ([12]aneN(3)S) has been synthesised, although upon crystallization from acetonitrile a product in which carbon dioxide had added...

Mercury(II) and lead (II) complexes of 1-Oxa-7-thia-4,10-diazacyclododecane ([12]aneN2OS) (1999)

Afshar, S., Marcus, S., Gahan, L. R., Hambley, T. W.

The mixed donor 12-membered macrocyclic ligand 1-oxa-7-thia-4,10-diazacyclododecane ([12]aneN2OS) has been synthesized and the mercury(II) and lead(II) complexes, [Hg([12]aneN2OS)(NO3)2] and...

Spin-orbit mixing and nephelauxetic effects in the electronic spectra of nickel(II)-encapsulating complexes involving nitrogen and sulfur donors (1997)

Stranger, R., McMahon, K. L., Gahan, L. R., Bruce, J. I., Hambley, T. W.

A study of spin-orbit mixing and nephelauxetic effects in the electronic spectra of nickel(II)-encapsulating complexes involving mixed nitrogen and sulfur donors is reported. As the number of sulfur...

Spin-orbit mixing and nephelauxetic effects in the electronic spectra of nickel(II)-encapsulating complexes involving nitrogen and sulfur donors (1997)

Stranger, R., McMahon, K. L., Gahan, L. R., Bruce, J. I., Hambley, T. W.

A study of spin-orbit mixing and nephelauxetic effects in the electronic spectra of nickel(II)-encapsulating complexes involving mixed nitrogen and sulfur donors is reported. As the number of sulfur...