Effects of methotrexate on normal articular cartilage in vitro and in vivo
Neidel, J., Sova, L., Schroers, B., Sintermann, F., Manzke, O., Bohlen, H.
OBJECTIVE—Methotrexate (MTX) has become the disease modifying drug of choice for the treatment of rheumatoid arthritis (RA). Direct effects of MTX on articular cartilage in vivo and in vitro were...