BACKGROUND: The current literature supports that schizophrenia (and bipolar disorders) appear to be associated with a higher prevalence of type 2 diabetes. Because of the silent nature of diabetes...
Truyen, I., De Grijse, J., Van Schravendijk, C., De Smet, D., Decochez, K., Vandemeulebroucke, E., ...
Aims/Hypothesis Insulin resistance has been proposed as a risk factor for type 1 diabetes. We investigated whether adiponectin, an insulin sensitiser, can serve as an additional predictive marker for...
Beckers, C, Mertens, I, Peeters, A, Van Gaal, L, Van Hul, W
Objective: To investigate whether pathogenic melanocortin-4 receptor (MC4R) mutations are a common cause of obesity in Belgium.
Engelen, W, Vertommen, J, De Leeuw, I, Van Gaal, L
OBJECTIVE: The primary objective was to compare the antioxidant activity of micronised fenofibrate 200 mg to 400 IU of vitamin E and placebo, on the LDL and VLDL particles of patients with type 1...
Kolanowski, J, Scheen, A, Van Gaal, L
OBJECTIVE: Assessment of the effects of orlistat 120 mg three times daily vs placebo on weight loss and serum lipids in obese hypercholesterolemic patients. DESIGN: A 24 week multicentre,...
Corthouts, B, Wauters, M, Peiffer, F, De Leeuw, I, ...
Plasminogen activator inhibitor type 1 (PAI-1), an inhibitor of fibrinolysis and an important and independent cardiovascular risk factor, has been shown to be elevated in obesity and type 2 diabetes....
Mertens, I, Rankinen, T, Chagnon, M, Bouchard, C, Van Gaal, L
Leptin receptors are present on p-cells as well as on muscle and fat cells, thus enabling leptin to modulate both insulin secretion and insulin action. Leptin inhibits especially the...
Muls, E, Kolanowski, J, Scheen, André, Van Gaal, L
OBJECTIVE: Assessment of the effects of orlistat 120 mg three times daily vs placebo on weight loss and serum lipids in obese hypercholesterolemic patients. DESIGN: A 24 week multicentre,...
Visceral fat is a determinant of PAI-1 activity in diabetic and non diabetic obese women (1999)
Mertens, I, Corthouts, B, Wauters, M, Peiffer, F, De Leeuw, I, ...
Increased procarboxypeptidase U levels in type II diabetes (1999)
Van Gaal, L, Schatteman, K, Goossens, Franky; U0006629, Mertens, I, Scharpe, S, De Leeuw, I, ...
Leptin receptor gene polymorphisms are associated with insulin in obese diabetic women (1999)
Wauters, M, Rankinen, T, Mertens, I, Chagnon, M, Bouchard, C, Van Gaal, L
Carbohydrate-induced thermogenesis in obese women. Effect of insulin and catecholamines (1999)
Van Gaal, L, Mertens, I, Vansant, Margareta; U0016427, De Leeuw, I
Results of studies on diet-induced thermogenesis in obese persons are contradictory. A number of factors have been postulated to mediate the obligatory and facultative component of thermogenesis....
The dense LDL phenotype and NIDDM. Association with lipoprotein levels and visceral obesity (1998)
Van Gaal, L, Wauters, M, Mertens, I, Peiffer, F, De Leeuw, I, Despres, JP
Are leptin levels dependent on body fat distribution in obese men and women? (1998)
Wauters, M, Mertens, I, Considine, R, De Leeuw, I, Van Gaal, L
Leptin levels are strongly related to total body fat. It is however not yet clear if leptin is also related to visceral fat accumulation or not. In this study, we investigated whether leptin is also...
Depot-specific differences in adipose tissue gene expression in lean and obese subjects. (1998)
Lefebvre, A M, Laville, M, Vega, N, Riou, J P, Van Gaal, L, Auwerx, J, ...
Intra-abdominal and subcutaneous adipose tissue display important metabolic differences that underlie the association of visceral, but not subcutaneous, fat with obesity-related cardiovascular and...
OBJECTIVE: To assess the effects of BMI at baseline and on-treatment weight change on the lipid-lowering efficacy of diet plus fibric acid derivatives (fibrates) in hypercholesterolemic adults....
Gezond vermageren. Een richtlijn voor het behandelen van overgewicht. (1997)
Vervaet, Myriam, BOGAERT, M, VAN GAAL, L, Van Winckel, Myriam, BORMS, J
Usefulness of fluoxetine in obese non-insulin-dependent diabetics: a multicenter study. (1996)
Daubresse, J C, Kolanowski, J, Krzentowski, G, Kutnowski, M, Scheen, André, Van Gaal, L
Weight reduction is essential in the management of most non-insulin-dependent diabetics, but this therapeutical goal is difficult to obtain. In this double-blind parallel study, 82...
ACE-inhibitoren : een stand van zaken (1992)
HERMAN, A, VERPOOTEN, G, DEGAUTE, J, FAGARD, R, Duprez, Daniel, VAN GAAL, L
Passage de l'insuline U-40 à l'insuline U-100 : l'expérience belge (1992)
VAN GAAL, L, KRZENTOWSKI, G, Rottiers, Raoul, COUTURIER, E, MICHEL, G, LEFEBVRE, J
Fluoxetine therapy in obese diabetic and glucose intolerant patients. (1992)
Kutnowski, M, Daubresse, J C, Friedman, H, Kolanowski, J, Krzentowski, G, Scheen, André, ...
A double-blind placebo-controlled trial was conducted, involving 97 obese diabetic and glucose intolerant patients receiving either 60 mg fluoxetine daily (47 patients) or a placebo (50 patients); a...