Hilgert, Nele, Huentelman, Matthew, Thorburn, AQ, Fransen, Erik, Dieltjens, Nele, Meuller-Malesinska, M, ...
Hereditary hearing loss (HL) is a very heterogeneous trait, with 46 gene identifications for non-syndromic HL. Mutations in GJB2 cause up to half of all cases of severe-to-profound congenital...
Familial aggregation of tinnitus: a European multicentre study (2007)
Huyghe, J. R., Demeester, K., Topsakal, V., Van Eyken, E., Fransen, E., ...
Introduction and aim: Tinnitus is a common condition affecting approximately 20% of the older population. There is increasing evidence that changes in the central auditory system following cochlear...
KCNQ4: a gene for age-related hearing impairment? (2006)
Van Eyken, E, Van Laer, L, Fransen, E, Topsakal, V, Lemkens, N, Laureys, W, ...
Age-related hearing impairment (ARHI) is the most common sensory impairment among the elderly. It is a complex disorder influenced by genetic as well as environmental factors. SNPs in a candidate...
Speciation of nickel in surface waters measured with the Donnan membrane technique (2006)
VAN LAER, L, SMOLDERS, E, DEGRYSE, F, Janssen, Colin, De Schamphelaere, Karel
Clinical features of DFNA5. (2002)
De Leenheer, Els, VAN ZUYLEN, DA, VAN LAER, L, VAN CAMP, G, HUYGEN, PL, HUIZING, EH, ...
Further delineation of the DFNA5 phenotype: Results of speech recognition tests. (2002)
De Leenheer, Els, VAN ZUIJLEN, DA, VAN LAER, L, VAN CAMP, G, HUYGEN, P, HUIZING, EH, ...
A common founder for the 35delG GJB2 gene mutation in connexin 26 hearing impairment. (2001)
VAN LAER, L, Coucke, Paul, MUELLER, RF, FLOTHMANN, K, PRASAD, SD, CHAMBERLIN, GP, ...
Peene, P, Herpels, V, Van Laer, L, Baert, A L
Department of Radiology, University Hospitals K.U. Leuven, Belgium.
A novel locus for autosomal dominant nonsyndromic hearing loss, DFNA13, maps to chromosome 6p.
Brown, M R, Tomek, M S, Van Laer, L, Smith, S, Kenyon, J B, Van Camp, G, ...
Nonsyndromic hearing loss (NSHL) is the most common type of hearing impairment in the elderly. Environmental and hereditary factors play an etiologic role, although the relative contribution of each...
A gene for autosomal dominant nonsyndromic hearing loss (DFNA12) maps to chromosome 11q22-24.
Verhoeven, K, Van Camp, G, Govaerts, P J, Balemans, W, Schatteman, I, Verstreken, M, ...
We performed linkage analysis in a Belgian family with autosomal dominant midfrequency hearing loss, which has a prelingual onset and a nonprogressive course in most patients. We found LOD scores >6...
A novel locus for autosomal dominant nonsyndromic hearing loss, DFNA13, maps to chromosome 6p.
Brown, M R, Tomek, M S, Van Laer, L, Smith, S, Kenyon, J B, Van Camp, G, ...
Nonsyndromic hearing loss (NSHL) is the most common type of hearing impairment in the elderly. Environmental and hereditary factors play an etiologic role, although the relative contribution of each...
Van Laer, L, Vingerhoets, J, Vanham, G, Kestens, L, Bwayo, J, Otido, J, ...
The cellular immune responses to fractionated Haemophilus ducreyi antigens, coated on latex beads, were assessed in patients with chancroid and in controls, using an in vitro lymphocyte proliferation...
A common founder for the 35delG GJB2 gene mutation in connexin 26 hearing impairment
Van Laer, L, Coucke, P, Mueller, R, Caethoven, G, Flothmann, K, Prasad, S, ...
Fifty to eighty percent of autosomal recessive congenital severe to profound hearing impairment result from mutations in a single gene, GJB2, that encodes the protein connexin 26. One mutation of...
DFNA5: hearing impairment exon instead of hearing impairment gene?
Van Laer, L, Vrijens, K, Thys, S, Smith, R, Van Bockstaele, D R, ...
Methods: We performed transfection experiments in mammalian cell lines (HEK293T and COS-1) with green fluorescent protein (GFP) tagged wildtype and mutant DFNA5 and analysed cell death with flow...