Authors/writing Members:,, Daemen, Joost, Simoons, Maarten L., Wijns, William, Bagust, Adrian, Bos, Gert, ...
Abdelwahab, A., Gardner, M., Parkash, R., Basta, M., Sapp, J., Veltmann, C., ...
Introduction: Scar-related ventricular tachycardia (VT) is often unmappable. Data regarding the outcomes of ablation for mappable vs unmappable VT are lacking. Methods: Catheter ablation of...
Chang, W, Goldstein, P, Adgey, J, Granger, C B, Verheugt, F W A, ...
OBJECTIVES: To assess the impact of variation in prehospital care across distinct health care environments in ASSENT (assessment of the safety and efficacy of a new thrombolytic) -3 PLUS, a large (n...
Chang, W.C., Midodzi, W.K., Westerhout, C.M., Boersma, E., Cooper, J., Barnathan, E.S., ...
STUDY OBJECTIVE: International variation in the outcomes of patients with acute coronary syndromes (ACS) has been well reported. The relative contributions of patient, hospital, and country level...
Ottervanger, J.P., Armstrong, P., Barnathan, E.S., Boersma, E., Cooper, J.S., Ohman, E.M., ...
Background Immediate, as well as early, revascularisation is of benefit in patients with acute coronary syndromes (ACS) presenting with ST elevation. However, trials comparing invasive versus medical...
Long-term treatment with anticoagulation agents in combination with aspirin can be beneficial for the prevention of recurrent thrombotic events, although the limitations of current agents make their...
James, S.K., Armstrong, P., Barnathan, E., Califf, R., Lindahl, B., Siegbahn, A., ...
OBJECTIVES: We sought to evaluate C-reactive protein (CRP) and troponin T (TnT) as predictors of risk of the individual end points of mortality and myocardial infarction (MI) in a large cohort of...
Ottervanger, J.P., Armstrong, P., Barnathan, E.S., Boersma, E., Cooper, J.S., Ohman, E.M., ...
BACKGROUND: This study was designed to investigate long-term effects of the glycoprotein IIb/IIIa inhibitor abciximab in patients with acute coronary syndrome without ST elevation who were not...
Wallentin, L, Goldstein, P, Granger, CB, Danays, T, ...
Incidence and outcome of percutaneous coronary intervention in ASSENT-3 and ASSENT-3+ (2003)
Armstrong, P, Adgey, J, Wallentin, L, Goldstein, P, ...
Myocardial damage, inflammation and thrombin inhibition in unstable coronary artery disease (2003)
Oldgren, J, Wallentin, L, Grip, L, Linder, R, Nørgaard, B.L, Siegbahn, A
Aim Unstable coronary artery disease (CAD) is a multifactorial disease involving both thrombotic and inflammatory processes. We have assessed the time-course and the influence of thrombin inhibitors...
Troponin T levels in patients with acute coronary syndromes with or wityout renal dysfunction (2002)
Aviles, R.J., Askari, A.T., Lindahl, B., Wallentin, L., Jia, G., Ohman, E.M., ...
BACKGROUND: Among patients with suspected acute coronary syndromes, cardiac troponin T levels have prognostic value. However, there is concern that renal dysfunction may impair the prognostic value,...
Aviles, R.J., Newby, L.K., Califf, R.M., Lauer, M.S., Simoons, M.L., Berger, P., ...
BACKGROUND: Among patients with suspected acute coronary syndromes, cardiac troponin T levels have prognostic value. However, there is concern that renal dysfunction may impair the prognostic value,...
Hasdai, D., Behar, S., Wallentin, L., Danchin, N., Gitt, A.K., Boersma, E., ...
AIMS: To better delineate the characteristics, treatments, and outcomes of patients with acute coronary syndromes (ACS) in representative countries across Europe and the Mediterranean basin, and to...
James, S., Armstrong, P., Califf, R., Husted, S., Kontny, F., Niemminen, M., ...
AIMS: The safety and efficacy of abciximab in addition to low-molecular-weight-heparin as the primary medical treatment of acute coronary syndromes has not previously been investigated. METHODS AND...
James, S., Armstrong, P., Califf, R., Husted, S., Kontny, F., Niemminen, M., ...
Aims The safety and efficacy of abciximab in addition to low-molecular-weight-heparin as the primary medical treatment of acute coronary syndromes has not previously been investigated. Methods and...
Jernberg, T., Abrahamsson, P., Lindahl, B., Johanson, P., Wallentin, L., Dellborg, M.
Aims Prolongation of anticoagulant treatment might reduce subsequent cardiac events in patients with unstable coronary artery disease. Multilead ST-segment monitoring identifies patients with a high...
Diderholm, E., Andrén, B., Frostfeldt, G., Genberg, M., Jernberg, T., Lagerqvist, B., ...
Background In unstable coronary artery disease, ST-segment depression indicates a poor prognosis. We evaluated whether the effect of early revascularization and the extent of coronary lesions were...
Hasdai, D., Behar, S., Wallentin, L., Danchin, N., Gitt, A.K., Boersma, E., ...
Aims To better delineate the characteristics, treatments, and outcomes of patients with acute coronary syndromes (ACS) in representative countries across Europe and the Mediterranean basin, and to...
Husted, S.E., Wallentin, L., Lagerqvist, B., Kontny, F., Ståhle, E., Swahn, E.
Aims The FRISC II trial demonstrated that, for patients with unstable coronary artery disease, an early invasive strategy following acute treatment with dalteparin and aspirin, was superior to a more...
Jernberg, T, Lindahl, B, Wallentin, L
Aims The aim was to examine the early prognostic value of a combination of a continuous 12-lead ECG and troponin T in patients with chest pain and an ECG non-diagnostic for acute myocardial...
Adgey, J, Ardissino, D, Armstrong, P W, Aylward, P, Barbash, G, ...
BACKGROUND: Bolus fibrinolytic therapy facilitates early efficient institution of reperfusion therapy. Tenecteplase is a genetically engineered variant of alteplase with slower plasma clearance,...
Sätre, H., Holmvang, L., Wagner, G.S., Lindahl, B., Wallentin, L.
Aims Several studies have proved heparin useful in treating patients with unstable coronary artery disease. The present study investigates whether Selvester QRS scoring for estimation of myocardial...
Linder, R., Oldgren, J., Egberg, N., Grip, L., Larson, G., Siegbahn, A., ...
Aim This study evaluated a novel specific thrombin inhibitor, inogatran, in comparison with unfractionated heparin, with regard to markers for coagulation activity in patients with unstable coronary...
Näslund, U., Grip, L., Fischer-Hansen, J., Gundersen, T., Lehto, S., Wallentin, L.
Background A multicentre study permits rapid recruitment of a large number of patients. However, there is a risk of heterogeneities in end-point evaluations, as complex definitions of criteria are...
Oldgren, J., Linder, R., Grip, L., Siegbahn, A., Wallentin, L.
Aims Direct thrombin inhibitors have failed to prove superiority over unfractionated heparin in several clinical trials of unstable coronary artery disease. We have investigated the relationship...
Toss, H., Gnarpe, J., Gnarpe, H., Siegbahn, A., Lindahl, B., Wallentin, L.
Aim Increased levels of acute phase proteins, e.g. fibrinogen, are related to a poor outcome in unstable coronary artery disease, but the cause of inflammation is unknown. We therefore investigated...
Lindahl, B., Andrén, B., Ohlsson, J., Venge, P., Wallentin, L.
In 963 patients, participating in a randomized study of low molecular weight heparin in unstable coronary artery disease and followed for 5 months, troponin T was determined. In the 766 patients with...
Low molecular weight heparins: a valuable tool in the treatment of acute coronary syndromes (1996)
Standard heparin, low molecular weight heparin and aspirin are at present the only antithrombotic agents of proven value in the initial treatment of patients with an acute coronary syndrome. The...
LARSSON, H., ARESKOG, M., JONASSON, T., RINGQVIST, I., FELLENIUS, C., ...
The diagnostic and prognostic value of ambulatory ST recordings after admission to the CCU and before discharge was compared to a symptom-limited predischarge exercise test in 170 men with unstable...
LARSSON, H., JONASSON, T., RINGQVIST, I., FELLENIUS, C., WALLENTIN, L.
The diagnostic and prognostic value of ST recordings in unstable coronary artery disease were evaluated in 198 men below 70 years of age admitted to the coronary care unit because of chest pain due...
One-hundred-and-ninety-three men with unstable coronary artery disease (CAD) (i.e. unstable angina or a non-Q wave myocardial infarction) were randomized in a double-blind fashion to acetylsalicyclic...
Swahn, E, Areskog, M, Wallentin, L
In 276 men with suspected unstable coronary artery disease i.e. recurring chest pain of new onset, increasing symptoms of anginal chest pain in formerly stable angina pectoris or suspected non-Q-wave...
Effects of the platelet inhibitor ticlopidine on exercise tolerance in stable angina pectoris (1987)
Berglund, U., Lassvik, C., Wallentin, L.
Coronary blood flow might be reduced by platelet aggregates or by vasospasm induced by platelet-produced thromboxane A2. Therefore the effects of the platelet inhibitor ticlopidine (500 mg daily) on...
SWAHN, E., ARESKOG, M., WALLENTIN, L.
The safety of and the diagnostic information provided by a predischarge exercise test performed 2-7 days after admission to the coronary care unit (CCU) was evaluated in 400 patients less than 65...
Chang, W., Midodzi, W., Westerhout, C., Boersma, E., Cooper, J., Barnathan, E., ...
Study objective: International variation in the outcomes of patients with acute coronary syndromes (ACS) has been well reported. The relative contributions of patient, hospital, and country level...
Lagerqvist, B, Diderholm, E, Lindahl, B, Husted, S, Kontny, F, Ståhle, E, ...
Objective: To develop a scoring system for risk stratification and evaluation of the effect of an early invasive strategy for treatment of unstable coronary artery disease (CAD).
Cardiovascular risk factors and clinical presentation in acute coronary syndromes
Rosengren, A, Wallentin, L, Simoons, M, Gitt, A K, Behar, S, Battler, A, ...
Objective: To investigate the hypothesis that risk factors may be differently related to severity of acute coronary syndromes (ACS), with ST elevation used as a marker of severe ACS.
Welsh, R C, Chang, W, Goldstein, P, Adgey, J, Granger, C B, Verheugt, F W A, ...
Objectives: To assess the impact of variation in prehospital care across distinct health care environments in ASSENT (assessment of the safety and efficacy of a new thrombolytic) -3 PLUS, a large (n...