L. Yuan

Publication List Details

Period

1994 - 2009

Number

111

Co-Authors

Neutral Pion Electroproduction in the Resonance Region at High $Q^2$ (2009)

Villano, A. N., Stoler, P., Bosted, P. E., Connell, S. H., Dalton, M. M., Jones, M. K., ...

The process $ep \to e^{\prime}p^{\prime}\pi^0$ has been measured at $Q^2$ = 6.4 and 7.7 GeV/c$^2$)$^2$ in Jefferson Lab's Hall C. Unpolarized differential cross sections are reported in the virtual...

New measurements of the EMC effect in very light nuclei (2009)

Seely, J., Daniel, A., Gaskell, D., Arrington, J., Fomin, N., Solvignon, P., ...

New Jefferson Lab data are presented on the nuclear dependence of the inclusive cross section from 2H, 3He, 4He, 9Be and 12C for 0.3

Expected Performance of the ATLAS Experiment - Detector, Trigger and Physics (2008)

Abat, E., Abbott, B., Abdallah, J., Abdelalim, A. A., Abdesselam, A., ...

A detailed study is presented of the expected performance of the ATLAS detector. The reconstruction of tracks, leptons, photons, missing energy and jets is investigated, together with the performance...

Nachtmann Moments of the Proton and Deuteron Spin Structure Functions (2008)

Slifer, K., Rondon, O. A., Aghalaryan, A., Ahmidouch, A., Asaturyan, R., Bloch, F., ...

We perform a Nachtmann moment analysis of our measured proton and deuteron spin structure functions g1 and g2 in the resonance region at intermediate four momentum transfer. This analysis is the...

Electroproduction of Eta Mesons in the S11(1535) Resonance Region at High Momentum Transfer (2008)

Dalton, M. M., Adams, G. S., Ahmidouch, A., Angelescu, T., Arrington, J., Asaturyan, R., ...

The differential cross-section for the process p(e,e'p)eta has been measured at Q2 ~ 5.7 and 7.0 (GeV/c)2 for centre-of-mass energies from threshold to 1.8 GeV, encompassing the S11(1535) resonance,...

Dependence of noise in magnetic tunnel junction sensors on annealing field and temperature (2008)

Liou, Sy-Hwang, Zhang, Rui, Russek, Stephen, Yuan, L., Halloran, Sean T., Pappas, David P.

The minimum detectable field of magnetoresistive sensors is limited by their intrinsic noise. Magnetization fluctuations are one of the crucial noise sources and are related to the magnetization...

Transverse momentum dependence of semi-inclusive pion production (2007)

Mkrtchyan, H., Bosted, P. E., Adams, G. S., Ahmidouch, A., Angelescu, T., Arrington, J., ...

Cross sections for semi-inclusive electroproduction of charged pions ($\pi^{\pm}$) from both proton and deuteron targets were measured for $0.2

Quasifree Lambda, Sigma^0, and Sigma^- electroproduction from 1,2H, 3,4He, and carbon (2007)

Dohrmann, F., Ahmidouch, A., Armstrong, C. S., Arrington, J., Asaturyan, R., Avery, S., ...

Kaon electroproduction from light nuclei and hydrogen, using 1H, 2H, 3He, 4He, and Carbon targets has been measured at Jefferson Laboratory. The quasifree angular distributions of Lambda and Sigma...

Tuning Magnetic Microstructures of Reference Layer in Magnetic Tunneling Junctions (2007)

Yuan, L., Lin, Y. S., Wang, Dexin, Liou, Sy-Hwang

Magnetic microstructures in the reference layer in magnetic tunneling junctions (MTJs) are tuned by a reversal field under ambient conditions to investigate their effects on the magnetoresistance...

Parallel multiplexing of fibre optic white light interferometric and fibre Bragg grating sensors for local and global strain measurements (2007)

Yuan, L

A scheme, based on the parallel multiplexing of long gauge fibre optic white light interferometric (FOWLI) and fibre Bragg grating (FBG) sensors, is proposed to realize quasi-static local and global...

Composite-cavity-based Fabry-Perot interferometric strain sensors (2007)

Yuan, L, Sun, W

A composite-cavity-based Fabry-Perot interferometric strain sensor system is proposed to gain the minimum cross sensitivity to temperature and a high multiplexing capability at the same time. The...

Simultaneous long- and short-gauge strain measurement in spectral domain by a novel optical fiber sensor unit (2007)

Yuan, L, Sun, W, Jin, W

A novel fiber-optic sensor unit by combining fiber-optic white-light interferometry and fiber Bragg gratings is proposed for simultaneous long- and short-gauge strain measurements. A new demodulation...

Spherical Clusters of NiO Nanoshafts for Lithium-Ion Battery Anodes (2006)

Yuan, L., Guo, Z. P., Konstantinov, K., Munroe, P., Liu, H. K.

Spherical clusters of NiO nanoshafts were prepared using a simple, rapid, and easily scaled up method, i.e., chemical precipitation followed by thermal decomposition. The microstructural...

Spherical Clusters of NiO Nanoshafts for Lithium-Ion Battery Anodes (2006)

Yuan, L., Guo, Z. P., Konstantinov, K., Munroe, P., Liu, H. K.

Spherical clusters of NiO nanoshafts were prepared using a simple, rapid, and easily scaled up method, i.e., chemical precipitation followed by thermal decomposition. The microstructural...

Proton Spin Structure in the Resonance Region (2006)

Slifer, K., Tajima, S., Aghalaryan, A., Ahmidouch, A., Asaturyan, R., ...

We have examined the spin structure of the proton in the region of the nucleon resonances (1.085 GeV < W < 1.910 GeV) at an average four momentum transfer of Q^2 = 1.3 GeV^2. Using the Jefferson Lab...

Microcantilever Torque Magnetometery Study of Patterned Magnetic Films (2006)

Yuan, L., Gao, Lei, Sabiryanov, Ildar F., Liou, Sy-Hwang, Chabot, M. D., Min, D. H., ...

The study of the small, defined magnetic structures has attracted much attention due to interest in both technology applications and fundamental research in micromagnetism. Microcantilever torque...

Magnetic Force Microscopy Study of CoPtCrO Perpendicular Media With Superparamagnetic And Permanent Magnet Tips (2006)

Yuan, L., Gao, Lei, Nicholl, L., Liou, Sy-Hwang, Zheng, M., Abarra, E. N., ...

Magnetic force microscopy (MFM) has been widely used in the study of magnetic recording media. It requires high resolution MFM tips as well as better understanding of the obtained magnetic images. In...

Temperature dependence of magnetoresistance in magnetic tunnel junctions with different free layer structures (2006)

Yuan, L., Liou, Sy-Hwang, Wang, Dexin

The temperature and bias voltage dependence of magnetoresistance and the resistance of two types of magnetic tunnel junction (MTJ) samples were studied. These two types of MTJ samples have different...

Hypernuclear spectroscopy using the (e,e'K+) reaction (2006)

Yuan, L., Sarsour, M., Miyoshi, T., Zhu, X., Ahmidouch, A., Androic, D., ...

Also archived at: arXiv:nucl-ex/0408011 v1 10 Aug 2004 / The date stated on this paper is incorrect.

Hypernuclear spectroscopy using the (e,e'K+) reaction (2006)

Yuan, L., Sarsour, M., Miyoshi, T., Zhu, X., Ahmidouch, A., Androic, D., ...

Also archived at: arXiv:nucl-ex/0408011 v1 10 Aug 2004 / The date stated on this paper is incorrect.

Effects of ion-beam irradiation on the L10 phase transformation and their magnetic properties of FePt and PtMn films (Invited) (2006)

Lai, Chih-Huang, Huang, Sheng-Huang, Yang, Cheng-Han, Chiang, C.C., Liou, Sy-Hwang, Sellmyer, David J., ...

In this paper, we illustrate how to modify the structure and magnetic properties of L10 FePt and PtMn films using ion-beam irradiation. Highly ordered L10 FePt and PtMn phases were achieved directly...

Spherical Clusters of NiO Nanoshafts for Lithium-Ion Battery Anodes (2006)

Yuan, L., Guo, Z. P., Konstantinov, K., Munroe, P., Liu, H. K.

Spherical clusters of NiO nanoshafts were prepared using a simple, rapid, and easily scaled up method, i.e., chemical precipitation followed by thermal decomposition. The microstructural...

Spherical Clusters of NiO Nanoshafts for Lithium-Ion Battery Anodes (2006)

Yuan, L., Guo, Z. P., Konstantinov, K., Munroe, P., Liu, H. K.

Spherical clusters of NiO nanoshafts were prepared using a simple, rapid, and easily scaled up method, i.e., chemical precipitation followed by thermal decomposition. The microstructural...

Optical Calibration For Jefferson Lab HKS Spectrometer (2005)

Yuan, L., Tang, L.

In order to accept very forward angle scattering particles, Jefferson Lab HKS experiment uses an on-target zero degree dipole magnet. The usual spectrometer optics calibration procedure has to be...

Nuclear transparency from quasielastic 12C(e,e'p) (2005)

Rohe, D., Benhar, O., Armstrong, C. S., Asaturyan, R., Baker, O. K., Bueltmann, S., ...

We studied the reaction 12C(e,e'p) in quasielastic kinematics at momentum transfers between 0.6 and 1.8 (GeV/c)^2 covering the single-particle region. From this the nuclear transparency factors are...

Functional analysis of FP25K of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus (2005)

Wu, D., Deng, F., Sun, X., Wang, H, Yuan, L, Vlak, J.M., ...

The fp25k gene of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus (HearNPV) was studied. HearNPV fp25k gene transcription was found starting from about 18 h post-infection, and protein...

Functional analysis of FP25K of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus (2005)

Wu, D., Deng, F., Sun, X., Wang, H, Yuan, L, Vlak, J.M., ...

The fp25k gene of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus (HearNPV) was studied. HearNPV fp25k gene transcription was found starting from about 18 h post-infection, and protein...

Hypernuclear Spectroscopy using the (e,e'K+) Reaction (2004)

Yuan, L., Sarsour, M., Miyoshi, T., Zhu, Z., Ahmindouch, A., Androic, D., ...

A pioneering experiment in Lambda hypernuclear spectroscopy, undertaken at the Thomas Jefferson National Accelerator Facility (Jlab), was recently reported. The experiment used the high- precision,...

Correlated Strength in Nuclear Spectral Function (2004)

Rohe, D., Armstrong, C. S., Asaturyan, R., Baker, O. K., Bueltmann, S., Carasco, C., ...

We have carried out an (e,e'p) experiment at high momentum transfer and in parallel kinematics to measure the strength of the nuclear spectral function S(k,E) at high nucleon momenta k and large...

Bistable memory effect in chromium oxide junctions (2003)

Sokolov, A., Ovtchenkov, E., Yuan, L., Liou, Sy-Hwang, Doudin, B.

Magnetotransport properties of granular CrO2 /Cr2O3 films made of CrO2 crystals covered by 1- 2 nm native insulating Cr2O3 are presented. Electrical properties of a limited number of grains measured...

Bistable Memory Effect in Chromium Oxide Junctions (2003)

Sokolov, A., Yang, C. S., Ovtchenkov, E., Yuan, L., Liou, S. H.

Magnetotransport properties of granular CrO2/Cr2O3 films made of CrO2 crystals covered by 1-2 nm native insulating Cr2O3 are presented. Electrical properties of a limited number of grains measured in...

A Semi-Empirical Approach to the Viscosities of Polyelectrolyte Solutions. (1998)

Yuan,L., Dougherty,T. J., Stivala,S. S.

The concentration dependence of a number of polyelectrolytes was found to be adequately described by an equation eta(sp)/c = eta(infinity) x (1 + k/sq root of c)) as long as the concentration is not...

Structural Transformation of Immiscible Metals Induced by Mechanical Alloying (1997)

Wei, S., Yuan, L., Liu, W., Lu, K., Yang, Y.

X-ray absorption fine structure(XAFS) is used to investigate the local structural change of Fe60Cu40 and Fe80Cu20 with the ball milling time. The XAFS results verify that the solid solution of...

Structural Transformation of Immiscible Metals Induced by Mechanical Alloying (1997)

Wei, S., Yuan, L., Liu, W., Lu, K., Yang, Y.

X-ray absorption fine structure(XAFS) is used to investigate the local structural change of Fe60Cu40 and Fe80Cu20 with the ball milling time. The XAFS results verify that the solid solution of...

Structural Transformation of Immiscible Metals Induced by Mechanical Alloying (1997)

Wei, S., Yuan, L., Liu, W., Lu, K., Yang, Y.

X-ray absorption fine structure(XAFS) is used to investigate the local structural change of Fe60Cu40 and Fe80Cu20 with the ball milling time. The XAFS results verify that the solid solution of...

An Abductive Approach to Disjunctive Logic Programming (1994)

Jia-huai You, Li Yan Yuan, Randy Goebel, Y Goebel, L. Yuan, ...

this paper we answer these questions by formulating a semantics, the regular extension semantics, for disjunctive programs, and by presenting a sound and complete extension of the Eshghi-Kowalski...

Modification of the substrate specificity of an acyl-acyl carrier protein thioesterase by protein engineering.

Yuan, L, Voelker, T A, Hawkins, D J

The plant acyl-acyl carrier protein (ACP) thioesterases (TEs) are of biochemical interest because of their roles in fatty acid synthesis and their utilities in the bioengineering of plant seed oils....

High level expression in Escherichia coli of soluble, enzymatically active schistosomal hypoxanthine/guanine phosphoribosyltransferase and trypanosomal ornithine decarboxylase.

Craig, S P, Yuan, L, Kuntz, D A, McKerrow, J H, Wang, C C

The bacterial alkaline phosphatase (phoA) promoter and signal peptide have been used previously to control recombinant expression and secretion of eukaryotic proteins in Escherichia coli. Other...

Antibody-Secreting Cell Responses to Rotavirus Proteins in Gnotobiotic Pigs Inoculated with Attenuated or Virulent Human Rotavirus

Chang, K. O., Vandal, O. H., Yuan, L., Hodgins, D. C., Saif, L. J.

Because of their similarities to infants in mucosal immune responses and their susceptibility to human rotavirus (HRV) diarrhea, gnotobiotic pigs provide a useful model for rotaviral disease. In this...

Effects of Maternal Antibodies on Protection and Development of Antibody Responses to Human Rotavirus in Gnotobiotic Pigs

Hodgins, D. C., Kang, S. Y., DeArriba, L., Parreño, V., Ward, L. A., Yuan, L., ...

Although maternal antibodies can protect against infectious disease in infancy, they can also suppress active immune responses. The effects of circulating maternal antibodies, with and without...

Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model.

Ward, L A, Yuan, L, Rosen, B I, Tô, T L, Saif, L J

Gnotobiotic pigs were orally inoculated with virulent Wa strain (G1P1A[8]) human rotavirus (group 1), attenuated Wa rotavirus (group 2) or diluent (controls) and were challenged with virulent Wa...

Deletion of purE attenuates Brucella melitensis infection in mice.

Crawford, R M, Yuan, L, Hadfield, T L, Warren, R L, Drazek, E S, ...

We previously showed that a purE mutant (delta purE201) of Brucella melitensis 16M is attenuated for growth in cultured human monocytes (E. S. Drazek, H. H. Houng, R. M. Crawford, T. L. Hadfield, D....

Outer membrane protein of Neisseria meningitidis as a mucosal adjuvant for lipopolysaccharide of Brucella melitensis in mouse and guinea pig intranasal immunization models.

Van De Verg, L L, Hartman, A B, Bhattacharjee, A K, Tall, B D, Yuan, L, Sasala, K, ...

A mucosal vaccine against brucellosis consisting of the lipopolysaccharide (LPS) of Brucella melitensis complexed with the outer membrane protein (GBOMP) of group B Neisseria meningitidis was tested...

The importance of a lipopolysaccharide-initiated, cytokine-mediated host defense mechanism in mice against extraintestinally invasive Escherichia coli.

Cross, A, Asher, L, Seguin, M, Yuan, L, Kelly, N, Hammack, C, ...

Extraintestinally invasive Escherichia coli (EC) that possess both a complete LPS and K1 capsule evade both complement-mediated bacteriolysis and neutrophil-mediated killing. Since C3H/HeJ mice that...

Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease.

Yuan, L, Ward, L A, Rosen, B I, To, T L, Saif, L J

Neonatal gnotobiotic pigs orally inoculated with virulent (intestinal-suspension) Wa strain human rotavirus (which mimics human natural infection) developed diarrhea, and most pigs which recovered...

Possible role of a proteinase in endosporulation of Coccidioides immitis.

Yuan, L, Cole, G T, Sun, S H

We previously reported isolation of a serine proteinase from the soluble conidial wall fraction of Coccidioides immitis. The purified proteinase was identified as a polypeptide band of 36,000 Mr by...

Immunoreactivity of a surface wall fraction produced by spherules of Coccidioides immitis.

Cole, G T, Kirkland, T N, Franco, M, Zhu, S, Yuan, L, Sun, S H, ...

The membranous spherule outer wall (SOW) isolated from liquid cultures of Coccidioides immitis has been shown to elicit reactivity with human anti-Coccidioides antibody by immunofluorescence and the...

Isolation and characterization of an extracellular proteinase of Coccidioides immitis.

Yuan, L, Cole, G T

A proteinase isolated from the respiratory pathogen, Coccidioides immitis, was shown to have collagenolytic and elastinolytic activity, as well as the ability to cleave human serum immunoglobulin G...

Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans.

Vitiello, A, Ishioka, G, Grey, H M, Rose, R, Farness, P, LaFond, R, ...

Our goal is to use peptide epitopes that are recognized by cytotoxic T lymphocytes (CTL) as immunogens for the development of prophylactic and therapeutic vaccines with chronic hepatitis B virus...

Isolation of antigens with proteolytic activity from Coccidioides immitis.

Cole, G T, Zhu, S W, Pan, S C, Yuan, L, Kruse, D, Sun, S H

Three antigens with proteolytic activity have been isolated from crude, water-soluble fractions of the saprobic phase of the fungal pathogen Coccidioides immitis. Two proteinases, identified in our...

Viremia and Nasal and Rectal Shedding of Rotavirus in Gnotobiotic Pigs Inoculated with Wa Human Rotavirus

Azevedo, M. S., Yuan, L., Gonzalez, A., Nguyen, T. V., Pouly, S., ...

Respiratory symptoms with rotavirus shedding in nasopharyngeal secretions have been reported in children with and without gastrointestinal symptoms (Zheng et al., 1991, J. Med. Virol. 34:29-37). To...

Characterization of a proteinase inhibitor isolated from the fungal pathogen Coccidioides immitis.

Yuan, L, Cole, G T

A proteinase inhibitor was isolated from the cytosol and cell wall of the fungal respiratory pathogen Coccidioides immitis. The inhibitor was purified to apparent homogeneity by acid precipitation,...

Diphtheria and tetanus immunity among blood donors in Toronto

Yuan, L, Lau, W, Thipphawong, J, Kasenda, M, Xie, F, Bevilacqua, J

OBJECTIVE: To determine the diphtheria and tetanus antitoxin levels among blood donors in Toronto. DESIGN: Cross-sectional seroprevalence study. SETTING: Two fixed-site blood-donation clinics in...

Outcome of pulmonary tuberculosis treatment in the tertiary care setting -- Toronto 1992/93

Wobeser, W, Yuan, L, Naus, M

BACKGROUND: Completion of treatment of active cases of tuberculosis (TB) is the most important priority of TB control programs. This study was carried out to assess treatment completion for active...

Prevalence of Mycobacterium tuberculosis infection among injection drug users in Toronto

Rusen, I D, Yuan, L, Millson, M E

BACKGROUND: Injection drug users are at increased risk of Mycobacterium tuberculosis infection and active tuberculosis (TB). The primary objective of this study was to determine the prevalence of M....

Cytokine Responses in Gnotobiotic Pigs after Infection with Virulent or Attenuated Human Rotavirus

Azevedo, M. S. P., Yuan, L., Pouly, S., Gonzales, A. M., Jeong, K. I., Nguyen, T. V., ...

To understand the role of cytokines during rotavirus infection, we assessed the kinetics of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) (proinflammatory), IL-12 (Th1 inducer), gamma...

Changes in lymphocyte number and phenotype in seven lymphoid compartments after thermal injury.

Organ, B C, Antonacci, A C, Chiao, J, Chiao, J, Kumar, A, De Riesthal, H F, ...

Thermal injury is associated with dysfunction of host defense systems. The present study used flow cytometric immunofluorescence analyses to investigate changes in number and phenotype of lymphocytes...

Measles outbreak in 31 schools: risk factors for vaccine failure and evaluation of a selective revaccination strategy.

Yuan, L

OBJECTIVE: To examine the risk factors for measles vaccine failure and to evaluate the effectiveness of a selective revaccination strategy during a measles outbreak. DESIGN: Matched case-control...

Evaluation of a tuberculosis screening program for high-risk students in Toronto schools.

Yuan, L, Richardson, E, Kendall, P R

OBJECTIVE: To evaluate the effectiveness of a tuberculosis (TB) screening program for high-risk students in elementary and secondary schools. DESIGN: Cross-sectional study of the 1992-93 school...

Dominance Is the Major Genetic Basis of Heterosis in Rice as Revealed by Qtl Analysis Using Molecular Markers

Xiao, J., Li, J., Yuan, L., Tanksley, S. D.

A set of 194 F(7) lines derived from a subspecific rice cross showing strong F(1) heterosis was backcrossed to the two parents. The materials (388 BC(1)F(7) lines, 194 F(8) lines, two parents, F(1))...

Identification of trait-improving quantitative trait loci alleles from a wild rice relative, Oryza rufipogon.

Xiao, J, Li, J, Grandillo, S, Ahn, S N, Yuan, L, Tanksley, S D, ...

Wild species are valued as a unique source of genetic variation, but they have rarely been used for the genetic improvement of quantitative traits. To identify trait-improving quantitative trait loci...

Modification of the substrate specificity of an acyl-acyl carrier protein thioesterase by protein engineering.

Yuan, L, Voelker, T A, Hawkins, D J

The plant acyl-acyl carrier protein (ACP) thioesterases (TEs) are of biochemical interest because of their roles in fatty acid synthesis and their utilities in the bioengineering of plant seed oils....

High level expression in Escherichia coli of soluble, enzymatically active schistosomal hypoxanthine/guanine phosphoribosyltransferase and trypanosomal ornithine decarboxylase.

Craig, S P, Yuan, L, Kuntz, D A, McKerrow, J H, Wang, C C

The bacterial alkaline phosphatase (phoA) promoter and signal peptide have been used previously to control recombinant expression and secretion of eukaryotic proteins in Escherichia coli. Other...

Antibody-Secreting Cell Responses to Rotavirus Proteins in Gnotobiotic Pigs Inoculated with Attenuated or Virulent Human Rotavirus

Chang, K. O., Vandal, O. H., Yuan, L., Hodgins, D. C., Saif, L. J.

Because of their similarities to infants in mucosal immune responses and their susceptibility to human rotavirus (HRV) diarrhea, gnotobiotic pigs provide a useful model for rotaviral disease. In this...

Effects of Maternal Antibodies on Protection and Development of Antibody Responses to Human Rotavirus in Gnotobiotic Pigs

Hodgins, D. C., Kang, S. Y., DeArriba, L., Parreño, V., Ward, L. A., Yuan, L., ...

Although maternal antibodies can protect against infectious disease in infancy, they can also suppress active immune responses. The effects of circulating maternal antibodies, with and without...

Development of mucosal and systemic lymphoproliferative responses and protective immunity to human group A rotaviruses in a gnotobiotic pig model.

Ward, L A, Yuan, L, Rosen, B I, Tô, T L, Saif, L J

Gnotobiotic pigs were orally inoculated with virulent Wa strain (G1P1A[8]) human rotavirus (group 1), attenuated Wa rotavirus (group 2) or diluent (controls) and were challenged with virulent Wa...

Deletion of purE attenuates Brucella melitensis infection in mice.

Crawford, R M, Yuan, L, Hadfield, T L, Warren, R L, Drazek, E S, ...

We previously showed that a purE mutant (delta purE201) of Brucella melitensis 16M is attenuated for growth in cultured human monocytes (E. S. Drazek, H. H. Houng, R. M. Crawford, T. L. Hadfield, D....

Outer membrane protein of Neisseria meningitidis as a mucosal adjuvant for lipopolysaccharide of Brucella melitensis in mouse and guinea pig intranasal immunization models.

Van De Verg, L L, Hartman, A B, Bhattacharjee, A K, Tall, B D, Yuan, L, Sasala, K, ...

A mucosal vaccine against brucellosis consisting of the lipopolysaccharide (LPS) of Brucella melitensis complexed with the outer membrane protein (GBOMP) of group B Neisseria meningitidis was tested...

The importance of a lipopolysaccharide-initiated, cytokine-mediated host defense mechanism in mice against extraintestinally invasive Escherichia coli.

Cross, A, Asher, L, Seguin, M, Yuan, L, Kelly, N, Hammack, C, ...

Extraintestinally invasive Escherichia coli (EC) that possess both a complete LPS and K1 capsule evade both complement-mediated bacteriolysis and neutrophil-mediated killing. Since C3H/HeJ mice that...

Systematic and intestinal antibody-secreting cell responses and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease.

Yuan, L, Ward, L A, Rosen, B I, To, T L, Saif, L J

Neonatal gnotobiotic pigs orally inoculated with virulent (intestinal-suspension) Wa strain human rotavirus (which mimics human natural infection) developed diarrhea, and most pigs which recovered...

Possible role of a proteinase in endosporulation of Coccidioides immitis.

Yuan, L, Cole, G T, Sun, S H

We previously reported isolation of a serine proteinase from the soluble conidial wall fraction of Coccidioides immitis. The purified proteinase was identified as a polypeptide band of 36,000 Mr by...

Immunoreactivity of a surface wall fraction produced by spherules of Coccidioides immitis.

Cole, G T, Kirkland, T N, Franco, M, Zhu, S, Yuan, L, Sun, S H, ...

The membranous spherule outer wall (SOW) isolated from liquid cultures of Coccidioides immitis has been shown to elicit reactivity with human anti-Coccidioides antibody by immunofluorescence and the...

Isolation and characterization of an extracellular proteinase of Coccidioides immitis.

Yuan, L, Cole, G T

A proteinase isolated from the respiratory pathogen, Coccidioides immitis, was shown to have collagenolytic and elastinolytic activity, as well as the ability to cleave human serum immunoglobulin G...

Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans.

Vitiello, A, Ishioka, G, Grey, H M, Rose, R, Farness, P, LaFond, R, ...

Our goal is to use peptide epitopes that are recognized by cytotoxic T lymphocytes (CTL) as immunogens for the development of prophylactic and therapeutic vaccines with chronic hepatitis B virus...

Isolation of antigens with proteolytic activity from Coccidioides immitis.

Cole, G T, Zhu, S W, Pan, S C, Yuan, L, Kruse, D, Sun, S H

Three antigens with proteolytic activity have been isolated from crude, water-soluble fractions of the saprobic phase of the fungal pathogen Coccidioides immitis. Two proteinases, identified in our...

Viremia and Nasal and Rectal Shedding of Rotavirus in Gnotobiotic Pigs Inoculated with Wa Human Rotavirus

Azevedo, M. S., Yuan, L., Gonzalez, A., Nguyen, T. V., Pouly, S., ...

Respiratory symptoms with rotavirus shedding in nasopharyngeal secretions have been reported in children with and without gastrointestinal symptoms (Zheng et al., 1991, J. Med. Virol. 34:29-37). To...

Characterization of a proteinase inhibitor isolated from the fungal pathogen Coccidioides immitis.

Yuan, L, Cole, G T

A proteinase inhibitor was isolated from the cytosol and cell wall of the fungal respiratory pathogen Coccidioides immitis. The inhibitor was purified to apparent homogeneity by acid precipitation,...

Dominance Is the Major Genetic Basis of Heterosis in Rice as Revealed by Qtl Analysis Using Molecular Markers

Xiao, J., Li, J., Yuan, L., Tanksley, S. D.

A set of 194 F(7) lines derived from a subspecific rice cross showing strong F(1) heterosis was backcrossed to the two parents. The materials (388 BC(1)F(7) lines, 194 F(8) lines, two parents, F(1))...

Diphtheria and tetanus immunity among blood donors in Toronto

Yuan, L, Lau, W, Thipphawong, J, Kasenda, M, Xie, F, Bevilacqua, J

OBJECTIVE: To determine the diphtheria and tetanus antitoxin levels among blood donors in Toronto. DESIGN: Cross-sectional seroprevalence study. SETTING: Two fixed-site blood-donation clinics in...

Outcome of pulmonary tuberculosis treatment in the tertiary care setting -- Toronto 1992/93

Wobeser, W, Yuan, L, Naus, M

BACKGROUND: Completion of treatment of active cases of tuberculosis (TB) is the most important priority of TB control programs. This study was carried out to assess treatment completion for active...

Prevalence of Mycobacterium tuberculosis infection among injection drug users in Toronto

Rusen, I D, Yuan, L, Millson, M E

BACKGROUND: Injection drug users are at increased risk of Mycobacterium tuberculosis infection and active tuberculosis (TB). The primary objective of this study was to determine the prevalence of M....

Cytokine Responses in Gnotobiotic Pigs after Infection with Virulent or Attenuated Human Rotavirus

Azevedo, M. S. P., Yuan, L., Pouly, S., Gonzales, A. M., Jeong, K. I., Nguyen, T. V., ...

To understand the role of cytokines during rotavirus infection, we assessed the kinetics of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) (proinflammatory), IL-12 (Th1 inducer), gamma...

Changes in lymphocyte number and phenotype in seven lymphoid compartments after thermal injury.

Organ, B C, Antonacci, A C, Chiao, J, Chiao, J, Kumar, A, De Riesthal, H F, ...

Thermal injury is associated with dysfunction of host defense systems. The present study used flow cytometric immunofluorescence analyses to investigate changes in number and phenotype of lymphocytes...

Identification of trait-improving quantitative trait loci alleles from a wild rice relative, Oryza rufipogon.

Xiao, J, Li, J, Grandillo, S, Ahn, S N, Yuan, L, Tanksley, S D, ...

Wild species are valued as a unique source of genetic variation, but they have rarely been used for the genetic improvement of quantitative traits. To identify trait-improving quantitative trait loci...

Measles outbreak in 31 schools: risk factors for vaccine failure and evaluation of a selective revaccination strategy.

Yuan, L

OBJECTIVE: To examine the risk factors for measles vaccine failure and to evaluate the effectiveness of a selective revaccination strategy during a measles outbreak. DESIGN: Matched case-control...

Evaluation of a tuberculosis screening program for high-risk students in Toronto schools.

Yuan, L, Richardson, E, Kendall, P R

OBJECTIVE: To evaluate the effectiveness of a tuberculosis (TB) screening program for high-risk students in elementary and secondary schools. DESIGN: Cross-sectional study of the 1992-93 school...

Protein kinase C mediates the signal for interferon-gamma mRNA expression in cytotoxic T cells after their adhesion to laminin.

Li, Y Q, Kobayashi, M, Yuan, L, Wang, J, Matsushita, K, Hamada, J I, ...

A cytotoxic T-cell line, CTLL-2 cells, showed spreading after adhering to extracellular matrix proteins such as fibronectin (FN), laminin (LN) and hyarulonic acid (HA). The adhesion of CTLL-2 cells...

MTS1/p16/CDKN2 lesions in primary glioblastoma multiforme.

Moulton, T., Samara, G., Chung, W. Y., Yuan, L., Desai, R., Sisti, M., ...

The multiple tumor suppressor 1 (MTS1) gene encoding the p16 inhibitor of cyclin-dependent kinase 4 is deleted or mutated in a wide variety of human tumor cell lines, but the importance of this gene...

New developments in hepatitis A control.

Yuan, L.

An inactivated vaccine for hepatitis A was recently licensed in Canada. This is the first important development in control of the disease in 50 years. This article presents new information about the...

Vaccine storage and handling. Knowledge and practice in primary care physicians' offices.

Yuan, L., Daniels, S., Naus, M., Brcic, B.

OBJECTIVE: To assess the knowledge and practice of vaccine storage and handling in primary care physicians' offices. DESIGN: A cross-sectional study was conducted from August to December 1992. Staff...

Family physicians managing tuberculosis. Qualitative study of overcoming barriers.

Jackson, L., Yuan, L.

OBJECTIVE: To identify the types of non-clinical barriers family physicians face in the management of TB, and to suggest strategies for overcoming these barriers. DESIGN: Qualitative study based on...

Evaluation of an in vitro assay aimed at measuring protective antibodies against sporozoites.

Mellouk, S., Berbiguier, N., Druilhe, P., Sedegah, M., Galey, B., Yuan, L., ...

We have evaluated the in vitro biological activities of antibodies directed against sporozoites and compared them with their capacity to protect against challenge with both human and rodent malaria....

Enhancement of in vitro prostaglandin E2 production by mouse fibrosarcoma cells after co-culture with various anti-tumour effector cells.

Okada, F., Hosokawa, M., Hasegawa, J., Kuramitsu, Y., Nakai, K., Yuan, L., ...

We have previously reported that an increase in the production of immunosuppressive prostaglandin E2 by a QR tumour (QR-32) is accompanied by progressive growth of the tumour in syngeneic C57BL/6...

Transforming growth factor beta 1 (TGF-beta 1) produced in tumour tissue after chemotherapy acts as a lymphokine-activated killer attractant.

Kuramitsu, Y., Nishibe, M., Kobayashi, M., Togashi, Y., Yuan, L., Takizawa, M., ...

Using an under agarose migration (UAM) assay, we studied lymphokine-activated killer (LAK)-attractant activity in cultured conditioned medium of tumour tissues after chemotherapy as a possible...

A sequential treatment regimen with melatonin and all-trans retinoic acid induces apoptosis in MCF-7 tumour cells.

Eck, K. M., Yuan, L., Duffy, L., Ram, P. T., Ayettey, S., Chen, I., ...

Neoplastic events are marked by uncontrolled cell proliferation. One major focus of cancer research has been to identify treatments that reduce or inhibit cell growth. Over the years, various...