Lambert H. M. Janssen

Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation (1997)

Maliepaard, Marc, Mol De, Nico J., Tomasz, Maria, Gargiulo, Dario, Janssen, Lambert H.M., ...

Potential antitumour mitosenes: relationship between in vitro DNA interstrand cross-link formation and DNA damage in escherichia coli K-12 strains (1994)

Maliepaard, Marc, Mol De, Nico J., Janssen, Lambert H.M., Stratford, Ian J., Stephens, Miriam, ...

This investigation was aimed at determining the possible relationship between DNA interstrand cross-linking and the cytotoxic activity of potential antitumour mitosene compounds. Mitosenes,...

Reductive activation of potential antitumor mitosene compounds (1993)

Maliepaard, Marc, Mol De, Nico J., Janssen, Lambert H.M., Hoogvliet, Joop C., Neut Van Der, Wouter, Verboom, Willem, ...

Redox cycling of potential antitumor aziridinylquinones (1992)

Lusthof, Klaas J., Mol De, Nicolaas J., Richter, Wilma, Janssen, Lambert H.M., Butler, John, Hoey, Brigid M., ...

The formation of reactive oxygen intermediates (ROI) during redox cycling of newly synthetized potential antitumor 2,5-bis (1-aziridinyl)-1,4-benzoquinone (BABQ) derivatives has been studied by...