Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...
α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...
CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP (2008)
Zobalova, Renata, McDermott, Laura Fay, Stantic, Marina, Prokopova, Katerina, Dong, Lan-feng, Neuzil, Jiri
Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...
α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...
CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP (2008)
Zobalova, Renata, McDermott, Laura Fay, Stantic, Marina, Prokopova, Katerina, Dong, Lan-feng, Neuzil, Jiri
Yes
Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...
α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...
CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP (2008)
Zobalova, Renata, McDermott, Laura Fay, Stantic, Marina, Prokopova, Katerina, Dong, Lan-feng, Neuzil, Jiri
Daxx inhibits stress-induced apoptosis in cardiac myocytes (2008)
Zobalova, Renata, Cowie, Emma Angela, Chladova, Jaromira, Dong, Lan-feng, Neuzil, Jiri
The role of the death-associated protein Daxx in modulation of apoptosis induced in cardiac myocytes by oxidative stress was studied. Exposure of cultured cardiomyocyte-like cells to oxidative stress...
Daxx inhibits stress-induced apoptosis in cardiac myocytes (2008)
Zobalova, Renata, Cowie, Emma Angela, Chladova, Jaromira, Dong, Lan-feng, Neuzil, Jiri
The role of the death-associated protein Daxx in modulation of apoptosis induced in cardiac myocytes by oxidative stress was studied. Exposure of cultured cardiomyocyte-like cells to oxidative stress...
Neuzil, Jiri, Widen, Cecilia, Gellert, Nina, Cowie, Emma Angela, Zobalova, Renata, Dong, Lan-feng, ...
Yes
Neuzil, Jiri, Widen, Cecilia, Gellert, Nina, Cowie, Emma Angela, Zobalova, Renata, Dong, Lan-feng, ...
Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...
Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...
Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...
The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...
Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...
Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...
α-Tocopheryl succinate inhibits angiogenesis by disrupting paracrine FGF2 signalling (2007)
Neuzil, Jiri, Cowie, Emma Angela, Wang, Xiufang, Dong, Lan-feng, Stapelberg, Michael
Malignant mesothelioma (MM) cells enhanced proliferation of endothelial cells (ECs) as well as their angiogenesis in vitro by secretion of fibroblast growth factor-2 (FGF2). This effect was...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...
Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...
Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...
Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...
The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...
Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...
Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...
α-Tocopheryl succinate inhibits angiogenesis by disrupting paracrine FGF2 signalling (2007)
Neuzil, Jiri, Cowie, Emma Angela, Wang, Xiufang, Dong, Lan-feng, Stapelberg, Michael
Malignant mesothelioma (MM) cells enhanced proliferation of endothelial cells (ECs) as well as their angiogenesis in vitro by secretion of fibroblast growth factor-2 (FGF2). This effect was...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...
Neuzil, Jiri, Widen, Cecilia, Gellert, Nina, Cowie, Emma Angela, Zobalova, Renata, Dong, Lan-feng, ...
Ischemia-reperfusion (I/R) is a condition leading to serious complications due to death of cardiac myocytes. We used the cardiomyocyte-like cell line H9c2 to study the mechanism underlying cell...
Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...
Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...
Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...
The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...
Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...
Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...
α-Tocopheryl succinate inhibits angiogenesis by disrupting paracrine FGF2 signalling (2007)
Neuzil, Jiri, Cowie, Emma Angela, Wang, Xiufang, Dong, Lan-feng, Stapelberg, Michael
Malignant mesothelioma (MM) cells enhanced proliferation of endothelial cells (ECs) as well as their angiogenesis in vitro by secretion of fibroblast growth factor-2 (FGF2). This effect was...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...
Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)
Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri
The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...
Vitamin E analogues as anti-cancer agents: Lessons from studies with a-tocopheryl succinate (2006)
Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri
Yes
Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)
Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri
The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Neuzil, Jiri, Dong, Lan-feng, Wang, Xiufang, Zingg, Jea-Marc
α-Tocopheryl succinate (α-TOS), a redox-silent analogue of vitamin E, induces apoptosis in multiple cell lines in a selective manner, by activating the intrinsic pathway. Since it is a highly...
Neuzil, Jiri, Dong, Lan-feng, Wang, Xiufang, Zingg, Jea-Marc
α-Tocopheryl succinate (α-TOS), a redox-silent analogue of vitamin E, induces apoptosis in multiple cell lines in a selective manner, by activating the intrinsic pathway. Since it is a highly...
Ralph, Stephen John, Low, Pauline, Dong, Lan-feng, Lawen, Alfons, Neuzil, Jiri
Mitochondria are proving to be worthy targets for activating specific killing of cancer cells in tumors and a diverse range of mitochondrial targeted drugs are currently in clinical trial to...
Ralph, Stephen John, Low, Pauline, Dong, Lan-feng, Lawen, Alfons, Neuzil, Jiri
Mitochondria are proving to be worthy targets for activating specific killing of cancer cells in tumors and a diverse range of mitochondrial targeted drugs are currently in clinical trial to...
Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)
Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri
The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Neuzil, Jiri, Dong, Lan-feng, Wang, Xiufang, Zingg, Jea-Marc
α-Tocopheryl succinate (α-TOS), a redox-silent analogue of vitamin E, induces apoptosis in multiple cell lines in a selective manner, by activating the intrinsic pathway. Since it is a highly...
Ralph, Stephen John, Low, Pauline, Dong, Lan-feng, Lawen, Alfons, Neuzil, Jiri
Mitochondria are proving to be worthy targets for activating specific killing of cancer cells in tumors and a diverse range of mitochondrial targeted drugs are currently in clinical trial to...