Lance Wells

Use of cancer-specific yeast-secreted in vivobiotinylated recombinant antibodies for serum biomarker discovery (2008)

Scholler, Nathalie, Gross, Jennifer A, Garvik, Barbara, Wells, Lance, Liu, Yan, Loch, Christian M, ...

Abstract Background Strategies to discover circulating protein markers of ovarian cancer are urgently needed. We developed a novel technology that permits us to isolate recombinant antibodies...

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

Vosseller, Keith, Wells, Lance, Lane, M. Daniel, Hart, Gerald W.

Increased flux of glucose through the hexosamine biosynthetic pathway (HSP) is believed to mediate hyperglycemia-induced insulin resistance in diabetes. The end product of the HSP,...

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

Vosseller, Keith, Wells, Lance, Lane, M. Daniel, Hart, Gerald W.

Increased flux of glucose through the hexosamine biosynthetic pathway (HSP) is believed to mediate hyperglycemia-induced insulin resistance in diabetes. The end product of the HSP,...

Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery

Scholler, Nathalie, Gross, Jennifer A, Garvik, Barbara, Wells, Lance, Liu, Yan, Loch, Christian M, ...