Chemical Characterization of Organisms Isolated from Leprosy Patients
Beaman, Blain L., Kim, Kwang-Shin, Lanéelle, Marie A., Barksdale, Lane
Chemical analyses of the cell walls of organisms isolated in various parts of the world from cases of lepromatous and tuberculoid leprosy make possible their assignment to one of the three genera:...
Phenoloxidase Activity in Organisms Isolated from Lepromatous and Tuberculoid Leprosy
Beaman, LoVelle, Barksdale, Lane
Anaerobic corynebacteria (propionibacteria), isolated in pure culture from the plasma of a case of tuberculoid leprosy and from lepromata of cases of lepromatous leprosy, exhibited phenoloxidase...
Park-Williams Number 8 Strain of Corynebacterium diphtheriae
Lampidis, Theodore, Barksdale, Lane
Five clones of the Park-Williams number 8 strain of Corynebacterium diphtheriae, previously maintained in separate laboratories, were examined for their colonial and biochemical properties, for the...
Ultrastructural Changes in Bacteria Isolated from Cases of Leprosy
Freer, John, Kim, Kwang S., Krauss, M. R., Beaman, Lovelle, Barksdale, Lane
One of two groups of rod-shaped bacteria (bacilli) isolated from cases of human leprosy have been found, under certain cultural conditions, to give rise to unusual phenotypes. In electron micrographs...
Arden, Sheldon B., Chang, Woo-Hyun, Barksdale, Lane
In Corynebacterium diphtheriae and closely related neuraminidase-producing corynebacteria, we have found an N-acetylneuraminate (NAN) lyase activity which cleaves NAN into N-acetyl-d-mannosamine and,...
Cytochemical Reactions of Human Leprosy Bacilli and Mycobacteria: Ultrastructural Implications
Fisher, Clark A., Barksdale, Lane
Leprosy bacilli harvested from freshly biopsied tissue from cases of lepromatous, borderline and histoid leprosy were, in conjunction with Mycobacterium lepraemurium and representative mycobacteria,...
System for the Investigation of the Bacteriophage-directed Synthesis of Diphtherial Toxin
Matsuda, Morihiro, Barksdale, Lane
Lytic corynebacteriophage βhv64tox+ has been characterized, and methods for studying the expression of its tox+ gene in nontoxinogenic Corynebacterium diphtheriae strain C7s(−)tox− described....
Neuraminidase of Corynebacterium diphtheriae
Moriyama, Takafumi, Barksdale, Lane
Neuraminidase activity has been found in a variety of strains of Corynebacterium diphtheriae, both toxinogenic and nontoxinogenic. The enzyme has been shown to be intracellular, possibly associated...
Fisher, Clark A., Barksdale, Lane
Bacilli from a number of tissues excised from cases of lepromatous and borderline leprosy, unlike mycobacteria, were found to lose their acid-fastness after treatment with pyridine.
Crystalline Inclusions of Bacterium 22M
Kim, Kwang S., Barksdale, Lane
Crystalline inclusions occur in bacterium 22M. Arrays consist of parallel rows of polyhedral subunits (7.5 nm in diameter), 2.0 nm apart, with a distance of 3.0 nm between rows.
Genetic Analysis of tox+ and tox− Bacteriophages of Corynebacterium diphtheriae1
Holmes, Randall K., Barksdale, Lane
A series of mutants derived from the temperate corynebacteriophages βtox+, γtox−, and Ltox+ was isolated and characterized. In three-factor crosses between mutant β phages the relative map order...
Comparative Studies with tox+ and tox− Corynebacteriophages 1
Holmes, Randall K., Barksdale, Lane
The characteristics of nine inducible temperate corynebacteriophages designated αtox+, βtox+, Ptox+, γtox−, πtox+, Ktox−, ρtox−, Ltox+, and δtox+ have been compared. Virion morphology and...
Chemical Characterization of Organisms Isolated from Leprosy Patients
Beaman, Blain L., Kim, Kwang-Shin, Lanéelle, Marie A., Barksdale, Lane
Chemical analyses of the cell walls of organisms isolated in various parts of the world from cases of lepromatous and tuberculoid leprosy make possible their assignment to one of the three genera:...
Phenoloxidase Activity in Organisms Isolated from Lepromatous and Tuberculoid Leprosy
Beaman, LoVelle, Barksdale, Lane
Anaerobic corynebacteria (propionibacteria), isolated in pure culture from the plasma of a case of tuberculoid leprosy and from lepromata of cases of lepromatous leprosy, exhibited phenoloxidase...
Park-Williams Number 8 Strain of Corynebacterium diphtheriae
Lampidis, Theodore, Barksdale, Lane
Five clones of the Park-Williams number 8 strain of Corynebacterium diphtheriae, previously maintained in separate laboratories, were examined for their colonial and biochemical properties, for the...
Ultrastructural Changes in Bacteria Isolated from Cases of Leprosy
Freer, John, Kim, Kwang S., Krauss, M. R., Beaman, Lovelle, Barksdale, Lane
One of two groups of rod-shaped bacteria (bacilli) isolated from cases of human leprosy have been found, under certain cultural conditions, to give rise to unusual phenotypes. In electron micrographs...
Arden, Sheldon B., Chang, Woo-Hyun, Barksdale, Lane
In Corynebacterium diphtheriae and closely related neuraminidase-producing corynebacteria, we have found an N-acetylneuraminate (NAN) lyase activity which cleaves NAN into N-acetyl-d-mannosamine and,...
Cytochemical Reactions of Human Leprosy Bacilli and Mycobacteria: Ultrastructural Implications
Fisher, Clark A., Barksdale, Lane
Leprosy bacilli harvested from freshly biopsied tissue from cases of lepromatous, borderline and histoid leprosy were, in conjunction with Mycobacterium lepraemurium and representative mycobacteria,...
System for the Investigation of the Bacteriophage-directed Synthesis of Diphtherial Toxin
Matsuda, Morihiro, Barksdale, Lane
Lytic corynebacteriophage βhv64tox+ has been characterized, and methods for studying the expression of its tox+ gene in nontoxinogenic Corynebacterium diphtheriae strain C7s(−)tox− described....
Neuraminidase of Corynebacterium diphtheriae
Moriyama, Takafumi, Barksdale, Lane
Neuraminidase activity has been found in a variety of strains of Corynebacterium diphtheriae, both toxinogenic and nontoxinogenic. The enzyme has been shown to be intracellular, possibly associated...
Fisher, Clark A., Barksdale, Lane
Bacilli from a number of tissues excised from cases of lepromatous and borderline leprosy, unlike mycobacteria, were found to lose their acid-fastness after treatment with pyridine.
Crystalline Inclusions of Bacterium 22M
Kim, Kwang S., Barksdale, Lane
Crystalline inclusions occur in bacterium 22M. Arrays consist of parallel rows of polyhedral subunits (7.5 nm in diameter), 2.0 nm apart, with a distance of 3.0 nm between rows.
Genetic Analysis of tox+ and tox− Bacteriophages of Corynebacterium diphtheriae1
Holmes, Randall K., Barksdale, Lane
A series of mutants derived from the temperate corynebacteriophages βtox+, γtox−, and Ltox+ was isolated and characterized. In three-factor crosses between mutant β phages the relative map order...
Comparative Studies with tox+ and tox− Corynebacteriophages 1
Holmes, Randall K., Barksdale, Lane
The characteristics of nine inducible temperate corynebacteriophages designated αtox+, βtox+, Ptox+, γtox−, πtox+, Ktox−, ρtox−, Ltox+, and δtox+ have been compared. Virion morphology and...