Khoury, Muin J., Bertram, Lars, Boffetta, Paolo, Butterworth, Adam S., Chanock, Stephen J., Dolan, Siobhan M., ...
Genome-wide association studies (GWAS) have led to a rapid increase in available data on common genetic variants and phenotypes and numerous discoveries of new loci associated with susceptibility to...
Genome-wide association studies in Alzheimer's disease (2009)
Bertram, Lars, Tanzi, Rudolph E.
Genome-wide association studies (GWAS) have gained considerable momentum over the last couple of years for the identification of novel complex disease genes. In the field of Alzheimer's disease (AD),...
Genetic Research in Schizophrenia: New Tools and Future Perspectives (2008)
Genetically, schizophrenia is a complex disease whose pathogenesis is likely governed by a number of different risk factors. While substantial efforts have been made to identify the underlying...
Hamshere, Marian L., Holmans, Peter A., Avramopoulos, Dimitrios, Bassett, Susan S., Blacker, Deborah, Bertram, Lars, ...
Previous attempts to identify genetic loci conferring risk for late-onset Alzheimer's disease (LOAD) through linkage analysis have observed some regions of linkage in common. However, due to the...
Hamshere, Marian Lindsay, Holmans, Peter Alan, Avramopoulos, Dimitrios, Bassett, Susan S., Blacker, Deborah, Bertram, Lars, ...
Previous attempts to identify genetic loci conferring risk for late-onset Alzheimer's disease (LOAD) through linkage analysis have observed some regions of linkage in common. However, due to the...
Hamshere, Marian Lindsay, Holmans, Peter Alan, Avramopoulos, Dimitrios, Bassett, Susan S., Blacker, Deborah, Bertram, Lars, ...
Previous attempts to identify genetic loci conferring risk for late-onset Alzheimer's disease (LOAD) through linkage analysis have observed some regions of linkage in common. However, due to the...
Alzheimer's Disease: One Disorder, Too Many Genes? (2004)
Bertram, Lars, Tanzi, Rudolph E.
The research of Alzheimer's disease (AD) genetics has been extremely prolific over the past decade, and currently more than ten genes are reported to show either positive or negative evidence for...
Alzheimer's disease: one disorder, too many genes? (2004)
Bertram, Lars, Tanzi, Rudolph E.
The research of Alzheimer's disease (AD) genetics has been extremely prolific over the past decade, and currently more than 10 genes are reported to show either positive or negative evidence for...
Alzheimer's Disease: One Disorder, Too Many Genes? (2004)
Bertram, Lars, Tanzi, Rudolph E.
The research of Alzheimer's disease (AD) genetics has been extremely prolific over the past decade, and currently more than ten genes are reported to show either positive or negative evidence for...
A QTL genome scan of the metabolic syndrome and its component traits (2003)
McQueen, Matthew B, Bertram, Lars, Rimm, Eric B, Blacker, Deborah, Santangelo, Susan L
Abstract Background Because high blood pressure, altered lipid levels, obesity, and diabetes so frequently occur together, they are sometimes collectively referred to as the metabolic syndrome. While...
Saunders, Aleister J, Bertram, Lars, Mullin, Kristina, Sampson, Andrew J, Latifzai, Khushal, Basu, Sanjay, ...
Alpha-2-Macroglobulin (A2M) is a highly plausible candidate gene for Alzheimer's disease (AD) in a region of chromosome 12 that has numerous independent reports of genetic linkage. We previously...
Saunders, Aleister J., Bertram, Lars, Mullin, Kristina, Sampson, Andrew J., Latifzai, Khushal, Basu, Sanjay, ...
Alpha-2-Macroglobulin (A2M) is a highly plausible candidate gene for Alzheimer's disease (AD) in a region of chromosome 12 that has numerous independent reports of genetic linkage. We previously...
Saunders, Aleister J, Bertram, Lars, Mullin, Kristina, Sampson, Andrew J, Latifzai, Khushal, Basu, Sanjay, ...
Alpha-2-Macroglobulin (A2M) is a highly plausible candidate gene for Alzheimer's disease (AD) in a region of chromosome 12 that has numerous independent reports of genetic linkage. We previously...
Bochum, Univ., Diss., 1997.
Bochum, Univ., Diss., 1997.
The genetic epidemiology of neurodegenerative disease
Bertram, Lars, Tanzi, Rudolph E.
Gene defects play a major role in the pathogenesis of degenerative disorders of the nervous system. In fact, it has been the very knowledge gained from genetic studies that has allowed the...
The genetic epidemiology of neurodegenerative disease
Bertram, Lars, Tanzi, Rudolph E.
Gene defects play a major role in the pathogenesis of degenerative disorders of the nervous system. In fact, it has been the very knowledge gained from genetic studies that has allowed the...
Farris, Wesley, Mansourian, Stefan, Leissring, Malcolm A., Eckman, Elizabeth A., Bertram, Lars, Eckman, Christopher B., ...
The causes of cerebral accumulation of amyloid β-protein (Aβ) in most cases of Alzheimer’s disease (AD) remain unknown. We recently found that homozygous deletion of the insulin-degrading enzyme...
A QTL genome scan of the metabolic syndrome and its component traits
McQueen, Matthew B, Bertram, Lars, Rimm, Eric B, Blacker, Deborah, Santangelo, Susan L
Bertram, Lars, Lange, Christoph, Mullin, Kristina, Parkinson, Michele, Hsiao, Monica, Hogan, Meghan F., ...
Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder. To date four genes have been established to either cause early-onset autosomal-dominant AD (APP, PSEN1, and PSEN21–4)...
Khoury, Muin J., Bertram, Lars, Boffetta, Paolo, Butterworth, Adam S., Chanock, Stephen J., Dolan, Siobhan M., ...
Genome-wide association studies (GWAS) have led to a rapid increase in available data on common genetic variants and phenotypes and numerous discoveries of new loci associated with susceptibility to...
Genetic Research in Schizophrenia: New Tools and Future Perspectives
Genetically, schizophrenia is a complex disease whose pathogenesis is likely governed by a number of different risk factors. While substantial efforts have been made to identify the underlying...