Li, Jian, Gao, Fei, Li, Ning, Li, Shengting, Yin, Guangliang, Tian, Geng, ...
Abstract Background DNA methylation is a widely studied epigenetic mechanism known to correlate with gene repression and genomic stability. Development of sensitive methods for global detection of...
Schierup, Mikkel H, Mailund, Thomas, Li, Heng, Wang, Jun, Tjønneland, Anne, Vogel, Ulla, ...
Abstract Background A small region of about 70 kb on human chromosome 19q13.3 encompasses 4 genes of which 3, ERCC1 , ERCC2 , and PPP1R13L (aka RAI ) are related to DNA repair and cell survival, and...
Estimation of tumor heterogeneity using CGH array data (2009)
Wang, Kai, Li, Jian, Li, Shengting, Bolund, Lars, Wiuf, Carsten
Abstract Background Array-based comparative genomic hybridization (CGH) is a commonly-used approach to detect DNA copy number variation in whole genome-wide screens. Several statistical methods have...
Nexø, Bjørn A, Vogel, Ulla, Olsen, Anja, Nyegaard, Mette, Bukowy, Zuzanna, Rockenbauer, Eszter, ...
Abstract Background Previous results have suggested an association of the region of 19q13.3 with several forms of cancer. In the present study, we investigated 27 public markers within a previously...
Nexø, Bjørn A., Vogel, Ulla, Olsen, Anja, Nygaard, Mette, Bukowy, Zuzanna, Rockenbauer, Eszter, ...
Background Previous results have suggested an association of the region of 19q13.3 with several forms of cancer. In the present study, we investigated 27 public markers within a previously identified...
Niemann, Isa, Bolund, Lars, Sunde, Lone
BACKGROUND In twin pregnancies comprising a hydatidiform mole and a normal co-fetus, the ploidy of the mole is almost exclusively reported as diploid and very rarely as triploid. We aimed at...
Ruan, Jue, Li, Heng, Chen, Zhongzhong, Coghlan, Avril, Coin, Lachlan James M., Guo, Yiran, ...
TreeFam (http://www.treefam.org) was developed to provide curated phylogenetic trees for all animal gene families, as well as orthologue and paralogue assignments. Release 4.0 of TreeFam contains...
Kai Wang, Jian Li, Shengting Li, Lars Bolund, Carsten Wiuf, Lars Bolund, ...
© 2009 Wang et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Gorodkin, Jan, Cirera, Susanna, Hedegaard, Jakob, Gilchrist, Michael J, Panitz, Frank, Jørgensen, Claus, ...
Background Knowledge of the structure of gene expression is essential for mammalian transcriptomics research. We analyzed a collection of more than one million porcine expressed sequence tags (ESTs),...
2007 Gorodkin et Volume al. 8, Issue 4, Article R45 Open Access (2007)
Jan Gorodkin, Susanna Cirera, Jakob Hedegaard, Michael J Gilchrist, Frank Panitz, Claus Jørgensen, ...
Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
Genetics of healthy aging in europe (2007)
Franceschi, Claudio, Bezrukov, Vladyslav, Blanché, Hélène, Bolund, Lars, Christensen, Kaare, De Benedictis, Giovanna, ...
The aim of the 5-year European Union (EU)-Integrated Project GEnetics of Healthy Aging (GEHA), constituted by 25 partners (24 from Europe plus the Beijing Genomics Institute from China), is to...
PigGIS: Pig Genomic Informatics System (2007)
Ruan, Jue, Guo, Yiran, Li, Heng, Hu, Yafeng, Song, Fei, Huang, Xin, ...
Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their human homologs and...
Snap: an integrated SNP annotation platform (2007)
Li, Shengting, Ma, Lijia, Li, Heng, Vang, Søren, Hu, Yafeng, Bolund, Lars, ...
Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human genome. The aim of...
Jue Ruan, Yiran Guo, Heng Li, Yafeng Hu, Fei Song, Xin Huang, ...
Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their human homologs and...
WEGO: a web tool for plotting GO annotations (2006)
Jia Ye, Lin Fang, Hongkun Zheng, Yong Zhang, Jie Chen, Zengjin Zhang, ...
Unified, structured vocabularies and classifications freely provided by the Gene Ontology (GO) Consortium are widely accepted in most of the large scale gene annotation projects. Consequently, many...
doi:10.1093/nar/gkl969 Snap: an integrated SNP annotation platform (2006)
Shengting Li, Lijia Ma, Heng Li, Søren Vang, Yafeng Hu, Lars Bolund
Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human genome. The aim of...
WEGO: a web tool for plotting GO annotations (2006)
Ye, Jia, Fang, Lin, Zheng, Hongkun, Zhang, Yong, Chen, Jie, Zhang, Zengjin, ...
Unified, structured vocabularies and classifications freely provided by the Gene Ontology (GO) Consortium are widely accepted in most of the large scale gene annotation projects. Consequently, many...
PigGIS: Pig Genomic Informatics System (2006)
Ruan, Jue, Guo, Yiran, Li, Heng, Hu, Yafeng, Song, Fei, Huang, Xin, ...
Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their human homologs and...
TreeFam: a curated database of phylogenetic trees of animal gene families (2006)
Li, Heng, Coghlan, Avril, Ruan, Jue, Coin, Lachlan James, Hériché, Jean-Karim, Osmotherly, Lara, ...
TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as...
PigGIS: Pig Genomic Informatics System (2006)
Ruan, Jue, Guo, Yiran, Li, Heng, Hu, Yafeng, Song, Fei, Huang, Xin, ...
Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their human homologs and...
Pigs in sequence space: A 0.66X coverage pig genome survey based on shotgun sequencing (2005)
Wernersson, Rasmus, Schierup, Mikkel H, Jørgensen, Frank G, Gorodkin, Jan, Panitz, Frank, Stærfeldt, Hans-Henrik, ...
Abstract Background Comparative whole genome analysis of Mammalia can benefit from the addition of more species. The pig is an obvious choice due to its economic and medical importance as well as its...
Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing (2005)
Bmc Genomics, Rasmus Wernersson, Mikkel H Schierup, Frank G Jørgensen, Jan Gorodkin, Frank Panitz, ...
Research article
A Population Threshold for Functional Polymorphisms (2003)
Wong, Gane Ka-Shu, Yang, Zhiyong, Passey, Douglas A., Kibukawa, Miho, Paddock, Marcia, Liu, Chun-Rong, ...
We sequenced 114 genes (for DNA repair, cell cycle arrest, apoptosis, and detoxification)in a mixed human population and observed a sudden increase in the number of functional polymorphisms below a...
Rockenbauer, Eszter, Bendixen, Mette H., Bukowy, Zuzanna, Yin, Jiaoyang, Jacobsen, Nicklas R., Hedayati, Mohammad, ...
We have previously used single nucleotide polymorphisms to detect an association of basal cell carcinoma (BCC) in Caucasian Americans and Danes with the genome region 19q13.2-3, which contains...
Bross, Peter, Jespersen, Charlotte, Jensen, Thomas G., Andresen, Brage S., Kristensen, Morten Juhl, Winter, Vibeke, ...
We have used expression of human medium chain acyl-CoA dehydrogenase (MCAD) in Escherichia coli as a model system for dissecting the molecular effects of two mutations detected in patients with MCAD...
Bross, Peter, Jensen, Thomas G., Andresen, Brage S., Kjeldsen, Margrethe, Nandy, Andreas, Kølvraa, Steen, ...
Two-dimensional gel electrophoresis was used to study and compare wild type medium-chain acyl-CoA dehydrogenase (MCAD; EC 1.3.99.3) and missense mutant enzyme found in patients with MCAD deficiency....
Bross, Peter, Andresen, Brage S., Winter, Vibeke, Kräutle, Franz-Georg, Jensen, Thomas G., Nandy, Andreas, ...
The influence of co-overexpression of the bacterial chaperonins GroEL and GroES on solubility, tetramer formation and enzyme activity of three variants of heterologously-expressed human medium-chain...
A silent A to G mutation in exon 11 of the medium-chain acyl-CoA dehydrogenase (MCAD) gene (1993)
Andresen, Brage S., Kølvraa, Steen, Bross, Peter, Bolund, Lars, Curtis, Diana, Eiberg, Hans, ...
Gregersen, Niels, Andresen, Brage S., Bross, Peter, Winter, Vibeke, Rüdiger, Niels, Engst, Stefan, ...
A series of experiments has established the molecular defect in the medium-chain acyl-coenzyme A (CoA) dehydrogenase (MCAD) gene in a family with MCAD deficiency. Demonstration of intra-mitochondrial...
Gregersen, Niels, Andresen, Brage S., Bross, Peter, Winter, Vibeke, Rüdiger, Niels, Engst, Stefan, ...
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency (McKusick 20145) is the most common inherited defect of the beta-oxidation of fatty acid (Roe and Coates, 1989). It causes life-threatening...
A three allele Taql polymorphism at TOP1 gene (1990)
Sunde, Lone, Kjeldsen, Eigil, Andoh, Toshiwo, Keene, Jack D., Bolund, Lars
Limited cataloging.
A three allele TaqI polymorphism at TOP1 gene
Sunde, Lone, Kjeldsen, Eigil, Andoh, Toshiwo, Keene, Jack D., Bolund, Lars
Ringertz, Nils R., Carlsson, Sten-Anders, Ege, Thorfinn, Bolund, Lars
Inactive nuclei of chick erythrocyte resume RNA synthesis and increase in volume and dry mass in heterokaryons made by virus-induced fusion of human tumor cells (HeLa) with chick erythrocytes....
A Population Threshold for Functional Polymorphisms
Wong, Gane Ka-Shu, Yang, Zhiyong, Passey, Douglas A., Kibukawa, Miho, Paddock, Marcia, Liu, Chun-Rong, ...
We sequenced 114 genes (for DNA repair, cell cycle arrest, apoptosis, and detoxification)in a mixed human population and observed a sudden increase in the number of functional polymorphisms below a...
Pigs in sequence space: A 0.66X coverage pig genome survey based on shotgun sequencing
Wernersson, Rasmus, Schierup, Mikkel H, Jørgensen, Frank G, Gorodkin, Jan, Panitz, Frank, Stærfeldt, Hans-Henrik, ...
A microarray analysis of the rice transcriptome and its comparison to Arabidopsis
Ma, Ligeng, Chen, Chen, Liu, Xigang, Jiao, Yuling, Su, Ning, Li, Lin, ...
Arabidopsis and rice are the only two model plants whose finished phase genome sequence has been completed. Here we report the construction of an oligomer microarray based on the presently known and...
TreeFam: a curated database of phylogenetic trees of animal gene families
Li, Heng, Coghlan, Avril, Ruan, Jue, Coin, Lachlan James, Hériché, Jean-Karim, Osmotherly, Lara, ...
TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as...
WEGO: a web tool for plotting GO annotations
Ye, Jia, Fang, Lin, Zheng, Hongkun, Zhang, Yong, Chen, Jie, Zhang, Zengjin, ...
Unified, structured vocabularies and classifications freely provided by the Gene Ontology (GO) Consortium are widely accepted in most of the large scale gene annotation projects. Consequently, many...
Andresen, Brage Storstein, Bross, Peter, Jensen, Thomas G., Winter, Vibeke, Knudsen, Inga, Kølvraa, Steen, ...
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is a serious and potentially fatal inherited defect in the β-oxidation of fatty acids. Approximately 80% of patients with MCAD deficiency are...
A three allele TaqI polymorphism at TOP1 gene
Sunde, Lone, Kjeldsen, Eigil, Andoh, Toshiwo, Keene, Jack D., Bolund, Lars
Ringertz, Nils R., Carlsson, Sten-Anders, Ege, Thorfinn, Bolund, Lars
Inactive nuclei of chick erythrocyte resume RNA synthesis and increase in volume and dry mass in heterokaryons made by virus-induced fusion of human tumor cells (HeLa) with chick erythrocytes....
A Population Threshold for Functional Polymorphisms
Wong, Gane Ka-Shu, Yang, Zhiyong, Passey, Douglas A., Kibukawa, Miho, Paddock, Marcia, Liu, Chun-Rong, ...
We sequenced 114 genes (for DNA repair, cell cycle arrest, apoptosis, and detoxification)in a mixed human population and observed a sudden increase in the number of functional polymorphisms below a...
Pigs in sequence space: A 0.66X coverage pig genome survey based on shotgun sequencing
Wernersson, Rasmus, Schierup, Mikkel H, Jørgensen, Frank G, Gorodkin, Jan, Panitz, Frank, Stærfeldt, Hans-Henrik, ...
Zhang, Xiaoxiao, Snijders, Antoine, Segraves, Richard, Zhang, Xiuqing, Niebuhr, Anita, Albertson, Donna, ...
We have used array comparative genomic hybridization to map DNA copy–number changes in 94 patients with cri du chat syndrome who had been carefully evaluated for the presence of the characteristic...
A microarray analysis of the rice transcriptome and its comparison to Arabidopsis
Ma, Ligeng, Chen, Chen, Liu, Xigang, Jiao, Yuling, Su, Ning, Li, Lin, ...
Arabidopsis and rice are the only two model plants whose finished phase genome sequence has been completed. Here we report the construction of an oligomer microarray based on the presently known and...
TreeFam: a curated database of phylogenetic trees of animal gene families
Li, Heng, Coghlan, Avril, Ruan, Jue, Coin, Lachlan James, Hériché, Jean-Karim, Osmotherly, Lara, ...
TreeFam is a database of phylogenetic trees of gene families found in animals. It aims to develop a curated resource that presents the accurate evolutionary history of all animal gene families, as...
WEGO: a web tool for plotting GO annotations
Ye, Jia, Fang, Lin, Zheng, Hongkun, Zhang, Yong, Chen, Jie, Zhang, Zengjin, ...
Unified, structured vocabularies and classifications freely provided by the Gene Ontology (GO) Consortium are widely accepted in most of the large scale gene annotation projects. Consequently, many...
Andresen, Brage Storstein, Bross, Peter, Jensen, Thomas G., Winter, Vibeke, Knudsen, Inga, Kølvraa, Steen, ...
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is a serious and potentially fatal inherited defect in the β-oxidation of fatty acids. Approximately 80% of patients with MCAD deficiency are...
PigGIS: Pig Genomic Informatics System
Ruan, Jue, Guo, Yiran, Li, Heng, Hu, Yafeng, Song, Fei, Huang, Xin, ...
Pig Genomic Information System (PigGIS) is a web-based depository of pig (Sus scrofa) genomic learning mainly engineered for biomedical research to locate pig genes from their human homologs and...
Snap: an integrated SNP annotation platform
Li, Shengting, Ma, Lijia, Li, Heng, Vang, Søren, Hu, Yafeng, Bolund, Lars, ...
Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human genome. The aim of...
Gorodkin, Jan, Cirera, Susanna, Hedegaard, Jakob, Gilchrist, Michael J, Panitz, Frank, Jørgensen, Claus, ...
A resource consisting of one million porcine ESTs is described, providing an essential resource for annotation, comparative genomics, assembly of the pig genome sequence, and further porcine...
Disease-causing Mutations in Exon 11 of the Medium-Chain Acyl-CoA Dehydrogenase Gene
Andresen, Brage Storstein, Jensen, Thomas G., Bross, Peter, Knudsen, Inga, Winter, Vibeke, Kølvraa, Steen, ...
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is the most commonly recognized defect of the mitochondrial β-oxidation in humans. It is a potentially fatal, autosomal recessive inherited...
Ruan, Jue, Li, Heng, Chen, Zhongzhong, Coghlan, Avril, Coin, Lachlan James M., Guo, Yiran, ...
TreeFam (http://www.treefam.org) was developed to provide curated phylogenetic trees for all animal gene families, as well as orthologue and paralogue assignments. Release 4.0 of TreeFam contains...
Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP
Nexø, Bjørn A, Vogel, Ulla, Olsen, Anja, Nyegaard, Mette, Bukowy, Zuzanna, Rockenbauer, Eszter, ...
Estimation of tumor heterogeneity using CGH array data
Wang, Kai, Li, Jian, Li, Shengting, Bolund, Lars, Wiuf, Carsten