Lars Lannfelt

Proteasome-mediated effects on amyloid precursor protein processing at the γ-secretase site

Flood, Fiona, Murphy, Suzanne, Cowburn, Richard F., Lannfelt, Lars, Walker, Brian, Johnston, Janet A.

Aβ (β-amyloid) peptides are found aggregated in the cortical amyloid plaques associated with Alzheimer's disease neuropathology. Inhibition of the proteasome alters the amount of Aβ produced from...

Linkage analysis of schizophrenia with five dopamine receptor genes in nine pedigrees

Coon, Hilary, Byerley, William, Holik, John, Hoff, Mark, Myles-Worsley, Marina, Lannfelt, Lars, ...

Alterations in dopamine neurotransmission have been strongly implicated in the pathogenesis of schizophrenia for nearly 2 decades. Recently, the genes for five dopamine receptors have been cloned and...

Proteasome-mediated effects on amyloid precursor protein processing at the γ-secretase site

Flood, Fiona, Murphy, Suzanne, Cowburn, Richard F., Lannfelt, Lars, Walker, Brian, Johnston, Janet A.

Aβ (β-amyloid) peptides are found aggregated in the cortical amyloid plaques associated with Alzheimer's disease neuropathology. Inhibition of the proteasome alters the amount of Aβ produced from...

Linkage analysis of schizophrenia with five dopamine receptor genes in nine pedigrees

Coon, Hilary, Byerley, William, Holik, John, Hoff, Mark, Myles-Worsley, Marina, Lannfelt, Lars, ...

Alterations in dopamine neurotransmission have been strongly implicated in the pathogenesis of schizophrenia for nearly 2 decades. Recently, the genes for five dopamine receptors have been cloned and...

Circulating immune complexes of Aβ and IgM in plasma of patients with Alzheimer’s disease

Marcello, Andrea, Wirths, Oliver, Schneider-Axmann, Thomas, Degerman-Gunnarsson, Malin, Lannfelt, Lars, Bayer, Thomas A.

It has previously been shown that immune complexes (IC) of a given biomarker with class M immunoglobulins (IgM) provide better performances compared to the unbound biomarker in a number of cancer...