Lars Rydén

Cholesterol lowering is more important than pleiotropic effects of statins for endothelial function in patients with dysglycaemia and coronary artery disease (2008)

Settergren, Magnus, Böhm, Felix, Rydén, Lars, Pernow, John

Aims The importance of pleiotropic effects of statins on endothelial function and inflammatory markers was investigated in patients with dysglycaemia and coronary artery disease (CAD). Methods and...

The impact of glucose lowering treatment on long-term prognosis in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial (2008)

Mellbin, Linda G., Malmberg, Klas, Norhammar, Anna, Wedel, Hans, Rydén, Lars

Aims To explore the impact of glucose lowering treatment on prognosis in diabetic patients with myocardial infarction. Methods and results 1181 type 2 diabetic patients (mean age 68 years; 67%...

Glucose lowering treatment in patients with coronary artery disease is prognostically important not only in established but also in newly detected diabetes mellitus: a report from the Euro Heart Survey on Diabetes and the Heart (2008)

Anselmino, Matteo, Öhrvik, John, Malmberg, Klas, Standl, Eberhard, Rydén, Lars

Aims Glucose lowering (GL) therapy in patients with diabetes mellitus (DM) and coronary artery disease (CAD) is prognostically important. This report from the Euro Heart Survey on Diabetes and the...

Trends and contexts in European cardiology practice for the next 15 years: The Madrid Declaration: a report from the European Conference on the Future of Cardiology, Madrid, 2-3 June 2006 (2007)

Escaned, Javier, Rydén, Lars, Zamorano, José Luis, Poole-Wilson, Philip, Fuster, Valentin, Gitt, Anselm, ...

In the near future, the practice of cardiology in Europe will be strongly influenced by a complex interplay of epidemiological, social, economical, professional, and technological evolving factors....

Sex-related aspects on abnormal glucose regulation in patients with coronary artery disease (2007)

Dotevall, Annika, Rosengren, Annika, Bartnik, Malgorzata, Malmberg, Klas, Öhrvik, John, Simoons, Maarten, ...

Aim To investigate the prevalence of diabetes and impaired glucose regulation (IGR) in a large cohort of men and women with coronary artery disease (CAD), and to describe the effect of abnormal...

Sex-related aspects on abnormal glucose regulation in patients with coronary artery disease (2007)

Dotevall, Annika, Rosengren, Annika, Bartnik, Malgorzata, Malmberg, Klas, Öhrvik, John, Simoons, Maarten, ...

Aim To investigate the prevalence of diabetes and impaired glucose regulation (IGR) in a large cohort of men and women with coronary artery disease (CAD), and to describe the effect of abnormal...

Trends and contexts in European cardiology practice for the next 15 years: The Madrid Declaration: a report from the European Conference on the Future of Cardiology, Madrid, 2-3 June 2006 (2007)

Escaned, Javier, Rydén, Lars, Zamorano, José Luis, Poole-Wilson, Philip, Fuster, Valentin, Gitt, Anselm, ...

In the near future, the practice of cardiology in Europe will be strongly influenced by a complex interplay of epidemiological, social, economical, professional, and technological evolving factors....

The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe: The Euro Heart Survey on diabetes and the heart (2004)

Bartnik, Malgorzata, Rydén, Lars, Ferrari, Roberto, Malmberg, Klas, Pyörälä, Kalevi, Simoons, Maarten, ...

Aim The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD). Methods and...

Patient access to medical technology across Europe (2004)

Rydén, Lars, Stokoe, Graham, Breithardt, Gunter, Lindemans, Fred, Potgieter, Adriaan

Access to medical technology differs across Europe. Differences in funding and reimbursement systems create barriers for the adoption of new and innovative medical technology. It is obvious that a...

The Need for Resources for Clinical Research: Proceedings of a Policy Conference held at the European Heart House, 27-28 June 2002: Executive Summary (2003)

Bassand, Jean-Pierre, Martin, John, Rydén, Lars, Simoons, Maarten

The medical profession, in particular cardiologists, acknowledge the fact that during the last 30 years, much of the progress made in the field of medicine has resulted from fruitful and close...

Under utilisation of evidence-based treatment partial explanation for the unfavourable prognosis in diabetic patients with acute myocardial infarction (2003)

Norhammar, Anna, Malmberg, Klas, Rydén, Lars, Tornvall, Per, Stenestrand, Ulf, Wallentin, Lars, ...

Aims The prognosis after an acute myocardial infarction is worse for patients with diabetes mellitus than for those without. We investigated whether differences in the use of evidence-based treatment...

Pharmacological possibilities for protection against myocardial reperfusion injury (2002)

Wang, Qing-Dong, Pernow, John, Sjöquist, Per-Ove, Rydén, Lars

Reperfusion through thrombolysis or percutananeous coronary angioplasty is standard treatment in impending acute myocardial infarction. Although restoration of blood flow to the jeopardised...

Mortality prediction in diabetic patients with myocardial infarction: experiences from the DIGAMI study (1997)

Malmberg, Klas, Rydén, Lars, Hamsten, Anders, Herlitz, Johan, Waldenström, Anders, Wedel, Hans

Objectives: We analysed predictors of 1-year mortality following acute myocardial infarction in patients with diabetes mellitus by applying uni- and multivariate statistics on the DIGAMI cohort....

Coronary venous drug infusion in the ischaemic-reperfused isolated rat heart (1996)

Uriuda, Yozo, Wang, Qing-Dong, Li, Xing-San, Sjöquist, Per-Ove, Nordlander, Rolf, Rydén, Lars

Objectives: Coronary venous retroinfusion (CVR) has been used experimentally in large animals for selective drug delivery into ischaemic myocardium. It would be an advantage if CVR could also be used...

Antithrombotic activity of inogatran, a new low-molecular-weight inhibitor of thrombin, in a closed-chest porcine model of coronary artery thrombosis (1996)

Uriuda, Yozo, Wang, Qing-Dong, Grip, Lars, Rydén, Lars, Sjöquist, Per-Ove, Mattsson, Christer

Objective: To characterize the antithrombotic activitiy of inogatran per se in a porcine model of copper-coil-induced coronary artery thrombosis and to compare its effect with that of heparin and...

A new apparatus for detection of impending pacemaker failure in patients treated with implanted pacemakers (1970)

Rydén, Lars, Hedström, Per, Leijonhufvud, Sten

Authors' synopsisTechnical description of a device intended for prophylactic checking of implanted capacitor discharge pacemakers is given. Rate, leading edge amplitude, impulse duration, and time...

The Effect of Lignocaine on the Stimulation Threshold and Conduction Disturbances in Patients Treated with Pacemaker (1969)

Rydén, Lars, Korsgren, Magnus

Authors' SynopsisThe present study was carried out to see if lignocaine in therapeutic anti-arrhythmic dosages given to pacemaker-treated patients involved any risks of exit block. We conclude that...