Smiraglia, Dominic J, Kazhiyur-Mannar, Ramakrishnan, Oakes, Christopher C, Wu, Yue-Zhong, Liang, Ping, Ansari, Tahmina, ...
Abstract Background Restriction landmark genomic scanning (RLGS) is one of the most successfully applied methods for the identification of aberrant CpG island hypermethylation in cancer, as well as...
Wu, Jiejun, Wang, Shu-Huei, Potter, Dustin, Liu, Joseph C, Smith, Laura T, Wu, Yue-Zhong, ...
Abstract Background Previous studies of individual genes have shown that in a self-enforcing way, dimethylation at histone 3 lysine 9 (dimethyl-H3K9) and DNA methylation cooperate to maintain a...
Victor X. Jin, Meiyun Fan, Laura T. Smith, Ya Liyanarachchi, Pearlly S. Yan, ...
In breast cancer and normal estrogen target tissues, estrogen receptor-a (ERa) signaling results in the establishment of spatiotemporal patterns of gene expression. Whereas primary target gene...
An AscI Boundary Library for the Studies of Genetic and Epigenetic Alterations in CpG Islands (2002)
Dai, Zunyan, Weichenhan, Dieter, Wu, Yue-Zhong, Hall, Julia L, Rush, Laura J., Smith, Laura T., ...
Yamanaka, Ryuya, Kim, Gun-Do, Radomska, Hanna S., Lekstrom-Himes, Julie, Smith, Laura T., Antonson, Per, ...
CCAAT/enhancer binding protein (C/EBP) ɛ is a recently cloned member of the C/EBP family of transcription factors and is expressed exclusively in cells of hematopoietic origin. The human C/EBPɛ...
An AscI Boundary Library for the Studies of Genetic and Epigenetic Alterations in CpG Islands
Dai, Zunyan, Weichenhan, Dieter, Wu, Yue-Zhong, Hall, Julia L, Rush, Laura J., Smith, Laura T., ...
Knudson's two-hit hypothesis postulates that genetic alterations in both alleles are required for the inactivation of tumor-suppressor genes. Genetic alterations include small or large deletions and...
Smith, Laura T., Lin, Mauting, Brena, Romulo M., Lang, James C., Schuller, David E., Otterson, Gregory A., ...
The identification of tumor suppressor genes has classically depended on their localization within recurrent regions of loss of heterozygosity. According to Knudson's two-hit hypothesis, the...
Yamanaka, Ryuya, Kim, Gun-Do, Radomska, Hanna S., Lekstrom-Himes, Julie, Smith, Laura T., Antonson, Per, ...
CCAAT/enhancer binding protein (C/EBP) ɛ is a recently cloned member of the C/EBP family of transcription factors and is expressed exclusively in cells of hematopoietic origin. The human C/EBPɛ...
An AscI Boundary Library for the Studies of Genetic and Epigenetic Alterations in CpG Islands
Dai, Zunyan, Weichenhan, Dieter, Wu, Yue-Zhong, Hall, Julia L, Rush, Laura J., Smith, Laura T., ...
Knudson's two-hit hypothesis postulates that genetic alterations in both alleles are required for the inactivation of tumor-suppressor genes. Genetic alterations include small or large deletions and...
Smith, Laura T., Lin, Mauting, Brena, Romulo M., Lang, James C., Schuller, David E., Otterson, Gregory A., ...
The identification of tumor suppressor genes has classically depended on their localization within recurrent regions of loss of heterozygosity. According to Knudson's two-hit hypothesis, the...