Holbein, Sandra, Wengi, Agnieszka, Decourty, Laurence, Freimoser, Florian M., Jacquier, Alain, Dichtl, Bernhard
Cordycepin (3′ deoxyadenosine) is a biologically active compound that, when incorporated during RNA synthesis in vitro, provokes chain termination due to the absence of a 3′ hydroxyl moiety. We...
Decourty, Laurence, Saveanu, Cosmin, Rappsilber, Juri, Jacquier, Alain, ...
A genome-wide screen for synthetic lethal (SL) interactions with loss of the nuclear exosome cofactors Rrp47/Lrp1 or Air1 identified 3' --> 35' exonucleases, the THO complex required for mRNP...
Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins (2000)
Micheline Fromont-Racine, Andrew E. Mayes, Adeline Brunet-Simon, Jean-Christophe Rain, Alan Colley, Ian Dix, ...
A set of seven structurally related Sm proteins forms the core of the snRNP particles containing the spliceosomal U1, U2, U4 and U5 snRNAs. A search of the genomic sequence of Saccharomyces...
A functional network involved in the recycling of nucleocytoplasmic pre-60S factors
Lebreton, Alice, Saveanu, Cosmin, Decourty, Laurence, Rain, Jean-Christophe, Jacquier, Alain, Fromont-Racine, Micheline
Eukaryotic pre-ribosomes go through cytoplasmic maturation steps before entering translation. The nucleocytoplasmic proteins participating in these late stages of maturation are reimported to the...
Hmo1 Is Required for TOR-Dependent Regulation of Ribosomal Protein Gene Transcription▿ †
Berger, Axel B., Decourty, Laurence, Badis, Gwenaël, Nehrbass, Ulf, Jacquier, Alain, Gadal, Olivier
Ribosome biogenesis requires equimolar amounts of four rRNAs and all 79 ribosomal proteins (RP). Coordinated regulation of rRNA and RP synthesis by eukaryotic RNA polymerases (Pol) I, III, and II is...
Genome-Wide Protein Interaction Screens Reveal Functional Networks Involving Sm-Like Proteins
Fromont-Racine, Micheline, Mayes, Andrew E., Brunet-Simon, Adeline, Rain, Jean-Christophe, Colley, Alan, Dix, Ian, ...
A set of seven structurally related Sm proteins forms the core of the snRNP particles containing the spliceosomal U1, U2, U4 and U5 snRNAs. A search of the genomic sequence of Saccharomyces...
Decourty, Laurence, Saveanu, Cosmin, Zemam, Kenza, Hantraye, Florence, Frachon, Emmanuel, Rousselle, Jean-Claude, ...
Describing at a genomic scale how mutations in different genes influence one another is essential to the understanding of how genotype correlates with phenotype and remains a major challenge in...
Milligan, Laura, Decourty, Laurence, Saveanu, Cosmin, Rappsilber, Juri, Ceulemans, Hugo, Jacquier, Alain, ...
A genome-wide screen for synthetic lethal (SL) interactions with loss of the nuclear exosome cofactors Rrp47/Lrp1 or Air1 identified 3′→5′ exonucleases, the THO complex required for mRNP...
Holbein, Sandra, Wengi, Agnieszka, Decourty, Laurence, Freimoser, Florian M., Jacquier, Alain, Dichtl, Bernhard
Cordycepin (3′ deoxyadenosine) is a biologically active compound that, when incorporated during RNA synthesis in vitro, provokes chain termination due to the absence of a 3′ hydroxyl moiety. We...