Laurent Roybon

Stem Cell Plasticity Controlling Neuronal Differentiation Prior to Cell Transplantation (2006)

Roybon, Laurent

Parkinson's disease (PD) is the second most common neurodegenerative disease and affects 2% of the population over 65 years of age. The disease is characterized by the progressive loss of...

Fibroblast Growth Factor-20 Increases the Yield of Midbrain Dopaminergic Neurons Derived from Human Embryonic Stem Cells

Correia, Ana Sofia, Anisimov, Sergey V., Roybon, Laurent, Li, Jia-Yi, Brundin, Patrik

In the central nervous system, fibroblast growth factor (FGF)-20 has been reported to act preferentially on midbrain dopaminergic neurons. It also promotes the dopaminergic differentiation of stem...

Neurogenin2 Directs Granule Neuroblast Production and Amplification while NeuroD1 Specifies Neuronal Fate during Hippocampal Neurogenesis

Roybon, Laurent, Hjalt, Tord, Stott, Simon, Guillemot, Francois, Li, Jia-Yi, Brundin, Patrik

The specification and differentiation of dentate gyrus granule neurons in the hippocampus require temporally and spatially coordinated actions of both intrinsic and extrinsic molecules. The basic...