Laurent Schibler

A physical map of the bovine genome (2007)

Snelling, Warren M, Chiu, Readman, Schein, Jacqueline E, Hobbs, Matthew, Abbey, Colette A, Adelson, David L, ...

Abstract Background Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify...

A physical map of the bovine genome (2007)

Chiu, Readman, Schein, Jacqueline, Hobbs, Matthew, Abbey, Colette, Adelson, David, ...

ABSTRACT: BACKGROUND: Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify...

Quantitative trait loci linked to PRNPgene controlling health and production traits in INRA 401 sheep (2007)

Vitezica, Zulma G, Moreno, Carole R, Lantier, Frederic, Lantier, Isabelle, Schibler, Laurent, Roig, Anne, ...

Abstract In this study, the potential association of PrP genotypes with health and productive traits was investigated. Data were recorded on animals of the INRA 401 breed from the Bourges-La...

A physical map of the bovine genome (2007)

Snelling, W. M., Chiu, R., Schein, J. E., Hobbs, M., Abbey, C. A., Adelson, David Louis, ...

Background Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify genomic...

A physical map of the bovine genome (2007)

Snelling, W. M., Chiu, R., Schein, J. E., Hobbs, M., Abbey, C. A., Adelson, David Louis, ...

Background Cattle are important agriculturally and relevant as a model organism. Previously described genetic and radiation hybrid (RH) maps of the bovine genome have been used to identify genomic...

High-resolution comparative mapping among man, cattle and mouse suggests a role for repeat sequences in mammalian genome evolution (2006)

Schibler, Laurent, Roig, Anne, Mahe, Marie-Françoise, Laurent, Pascal, Hayes, Hélène, Rodolphe, François, ...

Abstract Background Comparative mapping provides new insights into the evolutionary history of genomes. In particular, recent studies in mammals have suggested a role for segmental duplication in...

Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation (2005)

Pailhoux, Eric, Vigier, Bernard, Schibler, Laurent, Cribiu, Edmond P, Cotinot, Corinne, Vaiman, Daniel

Abstract In goats, the PIS (polled intersex syndrome) mutation is responsible for both the absence of horns in males and females and sex-reversal affecting exclusively XX individuals. The mode of...

A first generation bovine BAC-based physical map (2004)

Schibler, Laurent, Roig, Anne, Mahé, Marie-Françoise, Save, Jean-Claude, Gautier, Mathieu, Taourit, Sead, ...

Abstract A first generation clone-based physical map for the bovine genome was constructed combining, fluorescent double digestion fingerprinting and sequence tagged site (STS) marker screening. The...

Cytogenetic mapping of 25 goat mammary gland Expressed Sequence Tags (ESTs) (2000)

Le Provost, Fabienne, Schibler, Laurent, Oustry-Vaiman, Anne, Martin, Patrice, Cribiu, Edmond P

Abstract Today, there is a shift towards a positional candidate approach in the molecular identification of genes. This study reports on an Expressed Sequence Tags (ESTs) mapping initiative in goats,...

Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes

Mulsant, Philippe, Lecerf, Frédéric, Fabre, Stéphane, Schibler, Laurent, Monget, Philippe, Lanneluc, Isabelle, ...

Ewes from the Booroola strain of Australian Mérino sheep are characterized by high ovulation rate and litter size. This phenotype is due to the action of the FecBB allele of a major gene named FecB,...

An Enhanced Linkage Map of the Sheep Genome Comprising More Than 1000 Loci

Maddox, Jillian F., Davies, Kizanne P., Crawford, Allan M., Hulme, Dennis J., Vaiman, Daniel, Cribiu, Edmond P., ...

A medium-density linkage map of the ovine genome has been developed. Marker data for 550 new loci were generated and merged with the previous sheep linkage map. The new map comprises 1093 markers...

Fine Mapping Suggests that the Goat Polled Intersex Syndrome and the Human Blepharophimosis Ptosis Epicanthus Syndrome Map to a 100-kb Homologous Region

Schibler, Laurent, Cribiu, Edmond P., Oustry-Vaiman, Anne, Furet, Jean-Pierre, Vaiman, Daniel

To clone the goat Polled Intersex Syndrome (PIS) gene(s), a chromosome walk was performed from six entry points at 1q43. This enabled 91 BACs to be recovered from a recently constructed goat BAC...

Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes

Mulsant, Philippe, Lecerf, Frédéric, Fabre, Stéphane, Schibler, Laurent, Monget, Philippe, Lanneluc, Isabelle, ...

Ewes from the Booroola strain of Australian Mérino sheep are characterized by high ovulation rate and litter size. This phenotype is due to the action of the FecBB allele of a major gene named FecB,...

An Enhanced Linkage Map of the Sheep Genome Comprising More Than 1000 Loci

Maddox, Jillian F., Davies, Kizanne P., Crawford, Allan M., Hulme, Dennis J., Vaiman, Daniel, Cribiu, Edmond P., ...

A medium-density linkage map of the ovine genome has been developed. Marker data for 550 new loci were generated and merged with the previous sheep linkage map. The new map comprises 1093 markers...

Fine Mapping Suggests that the Goat Polled Intersex Syndrome and the Human Blepharophimosis Ptosis Epicanthus Syndrome Map to a 100-kb Homologous Region

Schibler, Laurent, Cribiu, Edmond P., Oustry-Vaiman, Anne, Furet, Jean-Pierre, Vaiman, Daniel

To clone the goat Polled Intersex Syndrome (PIS) gene(s), a chromosome walk was performed from six entry points at 1q43. This enabled 91 BACs to be recovered from a recently constructed goat BAC...

A physical map of the bovine genome

Snelling, Warren M, Chiu, Readman, Schein, Jacqueline E, Hobbs, Matthew, Abbey, Colette A, Adelson, David L, ...

A new physical map of the bovine genome has been constructed by integrating data from genetic and radiation hybrid maps, and a new bovine BAC map, with the bovine genome draft assembly.

Quantitative trait loci linked to PRNP gene controlling health and production traits in INRA 401 sheep

Vitezica, Zulma G, Moreno, Carole R, Lantier, Frederic, Lantier, Isabelle, Schibler, Laurent, Roig, Anne, ...

In this study, the potential association of PrP genotypes with health and productive traits was investigated. Data were recorded on animals of the INRA 401 breed from the Bourges-La Sapinière INRA...

A first generation bovine BAC-based physical map

Schibler, Laurent, Roig, Anne, Mahé, Marie-Françoise, Save, Jean-Claude, Gautier, Mathieu, Taourit, Sead, ...

A first generation clone-based physical map for the bovine genome was constructed combining, fluorescent double digestion fingerprinting and sequence tagged site (STS) marker screening. The BAC...

Cytogenetic mapping of 25 goat mammary gland Expressed Sequence Tags (ESTs)

Le Provost, Fabienne, Schibler, Laurent, Oustry-Vaiman, Anne, Martin, Patrice, Cribiu, Edmond P

Today, there is a shift towards a positional candidate approach in the molecular identification of genes. This study reports on an Expressed Sequence Tags (ESTs) mapping initiative in goats, based on...

New Insight on FGFR3-Related Chondrodysplasias Molecular Physiopathology Revealed by Human Chondrocyte Gene Expression Profiling

Schibler, Laurent, Gibbs, Linda, Benoist-Lasselin, Catherine, Decraene, Charles, Martinovic, Jelena, Loget, Philippe, ...

Endochondral ossification is the process by which the appendicular skeleton, facial bones, vertebrae and medial clavicles are formed and relies on the tight control of chondrocyte maturation....