Jacobs, Michael R., Bajaksouzian, Saralee, Bonomo, Robert A., Good, Caryn E., Windau, Anne R., Hujer, Andrea M., ...
The prevalence of Streptococcus pneumoniae serotype 6C, a recently recognized serotype that cross-reacts serologically with serotype 6A, was investigated. Isolates of serotype 6A in various...
David J. Ecker, Jared J. Drader, Jose Gutierrez, Abel Gutierrez, James C. Hannis, Amy Schink, ...
pathogen detection, mass spectrometry, broad-range PCR, ESI-TOF, bacteria, virus, strain typing
Rapid Identification of Emerging (2008)
Pathogens Coronavirus, Rangarajan Sampath, Steven A. Hofstadler, Lawrence B. Blyn, Mark W. Eshoo, Thomas A. Hall, ...
We describe a new approach for infectious disease surveillance that facilitates rapid identification of known and emerging pathogens. The process uses broad-range polymerase chain reaction (PCR) to...
Blyn, Lawrence B., Risen, Lisa M., Griffey, Richard H., Draper, David E.
Antibiotics that inhibit ribosomal function may do so by one of several mechanisms, including the induction of incorrect RNA folding or prevention of protein and/or RNA conformational...
Rapid Identification and Strain-Typing of Respiratory Pathogens for Epidemic Surveillance (1998)
Ecker, David J., Sampath, Rangarajan, Blyn, Lawrence B., Samant, Vivek, Russell, Kevin, Freed, Nikki, ...
Epidemic respiratory infections are responsible for extensive morbidity and mortality within both military and civilian populations. We describe a methodology to examine respiratory samples that...
Blyn, Lawrence B., Risen, Lisa M., Griffey, Richard H., Draper, David E.
Antibiotics that inhibit ribosomal function may do so by one of several mechanisms, including the induction of incorrect RNA folding or prevention of protein and/or RNA conformational transitions....
Graff, Judith, Cha, John, Blyn, Lawrence B., Ehrenfeld, Ellie
Utilization of internal ribosome entry segment (IRES) structures in the 5′ noncoding region (5′NCR) of picornavirus RNAs for initiation of translation requires a number of host cell factors whose...
MicC, a Second Small-RNA Regulator of Omp Protein Expression in Escherichia coli
Chen, Shuo, Zhang, Aixia, Blyn, Lawrence B., Storz, Gisela
In a previous bioinformatics-based search for novel small-RNA genes encoded by the Escherichia coli genome, we identified a region, IS063, located between the ompN and ydbK genes, that encodes an...
Rapid identification and strain-typing of respiratory pathogens for epidemic surveillance
Ecker, David J., Sampath, Rangarajan, Blyn, Lawrence B., Eshoo, Mark W., Ivy, Cristina, Ecker, Joseph A., ...
Epidemic respiratory infections are responsible for extensive morbidity and mortality within both military and civilian populations. We describe a high-throughput method to simultaneously identify...
Ecker, Joseph A., Massire, Christian, Hall, Thomas A., Ranken, Raymond, Pennella, Thuy-Trang D., Agasino Ivy, Cristina, ...
Members of the genus Acinetobacter are ubiquitous in soil and water and are an important cause of nosocomial infections. A rapid method is needed to genotype Acinetobacter isolates to determine...
Blyn, Lawrence B., Risen, Lisa M., Griffey, Richard H., Draper, David E.
Antibiotics that inhibit ribosomal function may do so by one of several mechanisms, including the induction of incorrect RNA folding or prevention of protein and/or RNA conformational transitions....
Graff, Judith, Cha, John, Blyn, Lawrence B., Ehrenfeld, Ellie
Utilization of internal ribosome entry segment (IRES) structures in the 5′ noncoding region (5′NCR) of picornavirus RNAs for initiation of translation requires a number of host cell factors whose...
MicC, a Second Small-RNA Regulator of Omp Protein Expression in Escherichia coli
Chen, Shuo, Zhang, Aixia, Blyn, Lawrence B., Storz, Gisela
In a previous bioinformatics-based search for novel small-RNA genes encoded by the Escherichia coli genome, we identified a region, IS063, located between the ompN and ydbK genes, that encodes an...
Rapid identification and strain-typing of respiratory pathogens for epidemic surveillance
Ecker, David J., Sampath, Rangarajan, Blyn, Lawrence B., Eshoo, Mark W., Ivy, Cristina, Ecker, Joseph A., ...
Epidemic respiratory infections are responsible for extensive morbidity and mortality within both military and civilian populations. We describe a high-throughput method to simultaneously identify...
Ecker, Joseph A., Massire, Christian, Hall, Thomas A., Ranken, Raymond, Pennella, Thuy-Trang D., Agasino Ivy, Cristina, ...
Members of the genus Acinetobacter are ubiquitous in soil and water and are an important cause of nosocomial infections. A rapid method is needed to genotype Acinetobacter isolates to determine...
Global Surveillance of Emerging Influenza Virus Genotypes by Mass Spectrometry
Sampath, Rangarajan, Russell, Kevin L., Massire, Christian, Eshoo, Mark W., Harpin, Vanessa, Blyn, Lawrence B., ...
Blyn, Lawrence B., Hall, Thomas A., Libby, Brian, Ranken, Raymond, Sampath, Rangarajan, Rudnick, Karl, ...
We have developed a PCR/electrospray ionization mass spectrometry (PCR/ESI-MS) assay for the rapid detection, identification, and serotyping of human adenoviruses. The assay employs a...
Hannis, James C., Manalili, Sheri M., Hall, Thomas A., Ranken, Raymond, White, Neill, Sampath, Rangarajan, ...
In this work we report on a high-throughput mass spectrometry-based technique for the rapid high-resolution identification of Campylobacter jejuni strain types. This method readily distinguishes C....
Jacobs, Michael R., Bajaksouzian, Saralee, Bonomo, Robert A., Good, Caryn E., Windau, Anne R., Hujer, Andrea M., ...
The prevalence of Streptococcus pneumoniae serotype 6C, a recently recognized serotype that cross-reacts serologically with serotype 6A, was investigated. Isolates of serotype 6A in various...
Eshoo, Mark W., Whitehouse, Chris A., Nalca, Aysegul, Zoll, Scott, Ecker, Joseph A., Hall, Thomas A., ...
The genus Orthopoxvirus contains several species of related viruses, including the causative agent of smallpox (Variola virus). In addition to smallpox, several other members of the genus are capable...
Rapid Determination of Quinolone Resistance in Acinetobacter spp.▿
Hujer, Kristine M., Hujer, Andrea M., Endimiani, Andrea, Thomson, Jodi M., Adams, Mark D., Goglin, Karrie, ...
In the treatment of serious bacterial infections, the rapid institution of appropriate antimicrobial chemotherapy may be lifesaving. Choosing the correct antibiotic or combination of antibiotics is...