Lawrence B. Lachman

Publication List Details

Period

1998 - 2005

Number

14

Co-Authors

Prime–boost vaccination with plasmid and adenovirus gene vaccines control HER2/neu+metastatic breast cancer in mice (2005)

Wang, Xiaoyan, Wang, Jian-Ping, Rao, Xiao-Mei, Price, Janet E, Zhou, Heshan S, Lachman, Lawrence B

Abstract Introduction Once metastasis has occurred, the possibility of completely curing breast cancer is unlikely, particularly for the 30 to 40% of cancers overexpressing the gene for HER2/ neu . A...

Alphavirus replicon particles containing the gene for HER2/neuinhibit breast cancer growth and tumorigenesis (2004)

Wang, Xiaoyan, Wang, Jian-Ping, Maughan, Maureen F, Lachman, Lawrence B

Abstract Introduction Overexpression of the HER2/ neu gene in breast cancer is associated with an increased incidence of metastatic disease and with a poor prognosis. Although passive immunotherapy...

Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neuin a murine mammary carcinoma model (2004)

Eralp, Yesim, Wang, Xiaoyan, Wang, Jian-Ping, Maughan, Maureen F, Polo, John M, Lachman, Lawrence B

Abstract Introduction The purpose of the present study was to determine whether cytotoxic chemotherapeutic agents administered prior to immunotherapy with gene vaccines could augment the efficacy of...

DNA Vaccination Against Metastatic Breast Cancer (2003)

Lachman, Lawrence B.

HER2/neu over-expression is found in 30-40% of breast cancer biopsy and is indicative of metastasis and poor prognosis. Although significant advances have been made in the treatment of breast cancer,...

DNA Vaccination Against Metastatic Breast Cancer (2003)

Lachman, Lawrence B.

HER2/neu over-expression is found in 30-40% of breast cancer biopsy and is indicative of metastasis and poor prognosis (1). Although significant advances have been made in the treatment of breast...

International Lymphokine Workshop (7th) Held in San Antonio Texas, on October 1-5, 1990. Lymphokines 1990: Cell Biology, Physiology, Therapy. Program Summaries and Abstracts. (1998)

Lachman, Lawrence B.

The purpose of these studies was to determine whether the tumoricidal phenotype of human blood monocytes would be affected by different activation signals. Human monocytes obtained by elutriation of...

Real-Time Quantitative PCR for Detection of Helicobacter pylori

He, Qiang, Wang, Jian-Ping, Osato, Michael, Lachman, Lawrence B.

Helicobacter pylori is one of the most common chronic infections in humans, in whom it is a key etiological factor in peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma, and...

Real-Time Quantitative PCR for Detection of Helicobacter pylori

He, Qiang, Wang, Jian-Ping, Osato, Michael, Lachman, Lawrence B.

Helicobacter pylori is one of the most common chronic infections in humans, in whom it is a key etiological factor in peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma, and...